| Full name: leucine rich repeat containing 3B | Alias Symbol: LRP15 | ||
| Type: protein-coding gene | Cytoband: 3p24.1 | ||
| Entrez ID: 116135 | HGNC ID: HGNC:28105 | Ensembl Gene: ENSG00000179796 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC3B | 116135 | 229085_at | -0.3266 | 0.2027 | |
| GSE26886 | LRRC3B | 116135 | 229085_at | -0.0245 | 0.8624 | |
| GSE45670 | LRRC3B | 116135 | 229085_at | -0.4242 | 0.0024 | |
| GSE53622 | LRRC3B | 116135 | 81854 | -1.9486 | 0.0000 | |
| GSE53624 | LRRC3B | 116135 | 81854 | -2.5672 | 0.0000 | |
| GSE63941 | LRRC3B | 116135 | 229085_at | -0.0153 | 0.9341 | |
| GSE77861 | LRRC3B | 116135 | 229085_at | -0.0389 | 0.5924 | |
| GSE97050 | LRRC3B | 116135 | A_23_P143857 | -0.4895 | 0.1720 | |
| TCGA | LRRC3B | 116135 | RNAseq | -2.0591 | 0.0330 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by LRRC3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC3B | 116135 | 0 | 18 | 12 | |
| GSE20123 | LRRC3B | 116135 | 0 | 18 | 12 | |
| GSE43470 | LRRC3B | 116135 | 0 | 20 | 23 | |
| GSE46452 | LRRC3B | 116135 | 2 | 17 | 40 | |
| GSE47630 | LRRC3B | 116135 | 1 | 24 | 15 | |
| GSE54993 | LRRC3B | 116135 | 6 | 2 | 62 | |
| GSE54994 | LRRC3B | 116135 | 1 | 32 | 20 | |
| GSE60625 | LRRC3B | 116135 | 5 | 0 | 6 | |
| GSE74703 | LRRC3B | 116135 | 0 | 17 | 19 | |
| GSE74704 | LRRC3B | 116135 | 0 | 12 | 8 | |
| TCGA | LRRC3B | 116135 | 2 | 68 | 26 |
Total number of gains: 17; Total number of losses: 228; Total Number of normals: 243.
Somatic mutations of LRRC3B:
Generating mutation plots.
Highly correlated genes for LRRC3B:
Showing top 20/594 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC3B | C1QTNF7 | 0.705496 | 6 | 0 | 5 |
| LRRC3B | GREM2 | 0.704112 | 6 | 0 | 6 |
| LRRC3B | OGN | 0.701423 | 6 | 0 | 6 |
| LRRC3B | CRBN | 0.693978 | 3 | 0 | 3 |
| LRRC3B | METTL7A | 0.693897 | 5 | 0 | 5 |
| LRRC3B | UTRN | 0.69326 | 5 | 0 | 5 |
| LRRC3B | OBP2A | 0.68641 | 3 | 0 | 3 |
| LRRC3B | CLEC3B | 0.686141 | 3 | 0 | 3 |
| LRRC3B | ANGPTL1 | 0.682053 | 6 | 0 | 6 |
| LRRC3B | NFIX | 0.679461 | 6 | 0 | 6 |
| LRRC3B | FCER1A | 0.679152 | 5 | 0 | 5 |
| LRRC3B | BCAP29 | 0.67787 | 3 | 0 | 3 |
| LRRC3B | LDB3 | 0.676411 | 5 | 0 | 5 |
| LRRC3B | ITIH5 | 0.6762 | 5 | 0 | 5 |
| LRRC3B | NR2F1 | 0.674302 | 3 | 0 | 3 |
| LRRC3B | CHRDL1 | 0.670752 | 5 | 0 | 5 |
| LRRC3B | KCNB1 | 0.670497 | 4 | 0 | 4 |
| LRRC3B | IL34 | 0.670265 | 4 | 0 | 4 |
| LRRC3B | MEIS1 | 0.667664 | 5 | 0 | 5 |
| LRRC3B | CYP21A2 | 0.666324 | 3 | 0 | 3 |
For details and further investigation, click here
