| Full name: LY6/PLAUR domain containing 1 | Alias Symbol: MGC29643 | ||
| Type: protein-coding gene | Cytoband: 2q21.2 | ||
| Entrez ID: 116372 | HGNC ID: HGNC:28431 | Ensembl Gene: ENSG00000150551 | OMIM ID: 610450 |
| Drug and gene relationship at DGIdb | |||
Expression of LYPD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYPD1 | 116372 | 212909_at | 0.7632 | 0.1350 | |
| GSE20347 | LYPD1 | 116372 | 212909_at | 0.2981 | 0.0234 | |
| GSE23400 | LYPD1 | 116372 | 212909_at | 0.1494 | 0.0036 | |
| GSE26886 | LYPD1 | 116372 | 212909_at | 0.5064 | 0.2130 | |
| GSE29001 | LYPD1 | 116372 | 212909_at | 0.6069 | 0.0022 | |
| GSE38129 | LYPD1 | 116372 | 212909_at | 0.5205 | 0.0150 | |
| GSE45670 | LYPD1 | 116372 | 212909_at | 0.7986 | 0.0071 | |
| GSE53622 | LYPD1 | 116372 | 36655 | 1.1010 | 0.0000 | |
| GSE53624 | LYPD1 | 116372 | 36655 | 1.8299 | 0.0000 | |
| GSE63941 | LYPD1 | 116372 | 212909_at | -1.2362 | 0.3715 | |
| GSE77861 | LYPD1 | 116372 | 212909_at | 0.0658 | 0.6300 | |
| GSE97050 | LYPD1 | 116372 | A_33_P3284129 | 1.1883 | 0.2094 | |
| SRP064894 | LYPD1 | 116372 | RNAseq | 2.3950 | 0.0000 | |
| SRP133303 | LYPD1 | 116372 | RNAseq | 1.0319 | 0.0003 | |
| SRP159526 | LYPD1 | 116372 | RNAseq | 3.1036 | 0.0000 | |
| SRP219564 | LYPD1 | 116372 | RNAseq | 0.9435 | 0.2372 | |
| TCGA | LYPD1 | 116372 | RNAseq | 1.0366 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by LYPD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYPD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYPD1 | 116372 | 3 | 4 | 23 | |
| GSE20123 | LYPD1 | 116372 | 3 | 4 | 23 | |
| GSE43470 | LYPD1 | 116372 | 2 | 1 | 40 | |
| GSE46452 | LYPD1 | 116372 | 1 | 4 | 54 | |
| GSE47630 | LYPD1 | 116372 | 5 | 2 | 33 | |
| GSE54993 | LYPD1 | 116372 | 0 | 6 | 64 | |
| GSE54994 | LYPD1 | 116372 | 10 | 1 | 42 | |
| GSE60625 | LYPD1 | 116372 | 0 | 3 | 8 | |
| GSE74703 | LYPD1 | 116372 | 2 | 1 | 33 | |
| GSE74704 | LYPD1 | 116372 | 2 | 2 | 16 | |
| TCGA | LYPD1 | 116372 | 22 | 13 | 61 |
Total number of gains: 50; Total number of losses: 41; Total Number of normals: 397.
Somatic mutations of LYPD1:
Generating mutation plots.
Highly correlated genes for LYPD1:
Showing top 20/737 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYPD1 | SULT1E1 | 0.750444 | 3 | 0 | 3 |
| LYPD1 | DCBLD1 | 0.712243 | 5 | 0 | 5 |
| LYPD1 | MAP4K1 | 0.703345 | 3 | 0 | 3 |
| LYPD1 | STRIP2 | 0.701924 | 4 | 0 | 4 |
| LYPD1 | ADAMTS12 | 0.678754 | 6 | 0 | 6 |
| LYPD1 | TTYH3 | 0.677671 | 6 | 0 | 5 |
| LYPD1 | CCR7 | 0.663435 | 3 | 0 | 3 |
| LYPD1 | LRRC8D | 0.661214 | 7 | 0 | 5 |
| LYPD1 | SEH1L | 0.658927 | 3 | 0 | 3 |
| LYPD1 | C16orf74 | 0.655605 | 5 | 0 | 5 |
| LYPD1 | PIK3CD | 0.649484 | 4 | 0 | 4 |
| LYPD1 | SPC24 | 0.648375 | 4 | 0 | 3 |
| LYPD1 | IRF6 | 0.644784 | 3 | 0 | 3 |
| LYPD1 | DBF4B | 0.644397 | 3 | 0 | 3 |
| LYPD1 | ZIC5 | 0.644358 | 4 | 0 | 4 |
| LYPD1 | DNAJC10 | 0.643666 | 6 | 0 | 5 |
| LYPD1 | CDH3 | 0.642849 | 7 | 0 | 6 |
| LYPD1 | UHRF1 | 0.641282 | 6 | 0 | 6 |
| LYPD1 | DNAJB11 | 0.639901 | 5 | 0 | 5 |
| LYPD1 | PSMC1 | 0.638254 | 4 | 0 | 3 |
For details and further investigation, click here
