| Full name: MAF bZIP transcription factor B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q12 | ||
| Entrez ID: 9935 | HGNC ID: HGNC:6408 | Ensembl Gene: ENSG00000204103 | OMIM ID: 608968 |
| Drug and gene relationship at DGIdb | |||
Expression of MAFB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAFB | 9935 | 218559_s_at | 0.9183 | 0.2182 | |
| GSE20347 | MAFB | 9935 | 218559_s_at | 0.0403 | 0.8953 | |
| GSE23400 | MAFB | 9935 | 218559_s_at | 0.5090 | 0.0021 | |
| GSE26886 | MAFB | 9935 | 218559_s_at | -1.0518 | 0.0053 | |
| GSE29001 | MAFB | 9935 | 218559_s_at | 0.1343 | 0.7828 | |
| GSE38129 | MAFB | 9935 | 218559_s_at | 0.3375 | 0.1385 | |
| GSE45670 | MAFB | 9935 | 218559_s_at | 0.5748 | 0.0119 | |
| GSE53622 | MAFB | 9935 | 95916 | 0.2630 | 0.0127 | |
| GSE53624 | MAFB | 9935 | 95916 | 0.1996 | 0.0164 | |
| GSE63941 | MAFB | 9935 | 218559_s_at | -1.3441 | 0.4297 | |
| GSE77861 | MAFB | 9935 | 218559_s_at | -0.4342 | 0.4512 | |
| GSE97050 | MAFB | 9935 | A_23_P17345 | 0.5714 | 0.1565 | |
| SRP007169 | MAFB | 9935 | RNAseq | -0.8191 | 0.0387 | |
| SRP008496 | MAFB | 9935 | RNAseq | -0.3541 | 0.2213 | |
| SRP064894 | MAFB | 9935 | RNAseq | 0.7182 | 0.0331 | |
| SRP133303 | MAFB | 9935 | RNAseq | 0.3938 | 0.1387 | |
| SRP159526 | MAFB | 9935 | RNAseq | 0.0521 | 0.8263 | |
| SRP193095 | MAFB | 9935 | RNAseq | -0.0200 | 0.9351 | |
| SRP219564 | MAFB | 9935 | RNAseq | 1.1878 | 0.0056 | |
| TCGA | MAFB | 9935 | RNAseq | 0.3835 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by MAFB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAFB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAFB | 9935 | 13 | 1 | 16 | |
| GSE20123 | MAFB | 9935 | 13 | 1 | 16 | |
| GSE43470 | MAFB | 9935 | 13 | 0 | 30 | |
| GSE46452 | MAFB | 9935 | 29 | 0 | 30 | |
| GSE47630 | MAFB | 9935 | 24 | 0 | 16 | |
| GSE54993 | MAFB | 9935 | 0 | 17 | 53 | |
| GSE54994 | MAFB | 9935 | 24 | 0 | 29 | |
| GSE60625 | MAFB | 9935 | 0 | 0 | 11 | |
| GSE74703 | MAFB | 9935 | 10 | 0 | 26 | |
| GSE74704 | MAFB | 9935 | 9 | 0 | 11 | |
| TCGA | MAFB | 9935 | 45 | 5 | 46 |
Total number of gains: 180; Total number of losses: 24; Total Number of normals: 284.
Somatic mutations of MAFB:
Generating mutation plots.
Highly correlated genes for MAFB:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAFB | GJB2 | 0.644315 | 4 | 0 | 3 |
| MAFB | WNT5A | 0.639059 | 3 | 0 | 3 |
| MAFB | NKPD1 | 0.634467 | 3 | 0 | 3 |
| MAFB | MAPK13 | 0.622449 | 4 | 0 | 4 |
| MAFB | TFCP2L1 | 0.611973 | 4 | 0 | 3 |
| MAFB | FAM83C | 0.607547 | 8 | 0 | 4 |
| MAFB | GJB6 | 0.604382 | 5 | 0 | 4 |
| MAFB | PPP1R14B | 0.598798 | 4 | 0 | 3 |
| MAFB | STON2 | 0.598352 | 3 | 0 | 3 |
| MAFB | SERPINB5 | 0.591673 | 8 | 0 | 5 |
| MAFB | S100A9 | 0.582967 | 6 | 0 | 3 |
| MAFB | DLX3 | 0.582658 | 3 | 0 | 3 |
| MAFB | ST3GAL1 | 0.580898 | 3 | 0 | 3 |
| MAFB | EFNA4 | 0.578593 | 6 | 0 | 3 |
| MAFB | P2RY2 | 0.571118 | 4 | 0 | 3 |
| MAFB | EPHA1 | 0.570311 | 4 | 0 | 3 |
| MAFB | GPR78 | 0.569658 | 3 | 0 | 3 |
| MAFB | AACS | 0.569166 | 6 | 0 | 5 |
| MAFB | DSG3 | 0.568157 | 8 | 0 | 3 |
| MAFB | SERINC5 | 0.566552 | 5 | 0 | 3 |
For details and further investigation, click here
