| Full name: mannosidase alpha class 2C member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 4123 | HGNC ID: HGNC:6827 | Ensembl Gene: ENSG00000140400 | OMIM ID: 154580 |
| Drug and gene relationship at DGIdb | |||
Expression of MAN2C1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAN2C1 | 4123 | 203668_at | -0.2423 | 0.4019 | |
| GSE20347 | MAN2C1 | 4123 | 203668_at | 0.0098 | 0.9593 | |
| GSE23400 | MAN2C1 | 4123 | 203668_at | -0.0490 | 0.4936 | |
| GSE26886 | MAN2C1 | 4123 | 203668_at | -0.1700 | 0.2158 | |
| GSE29001 | MAN2C1 | 4123 | 203668_at | -0.1076 | 0.7789 | |
| GSE38129 | MAN2C1 | 4123 | 203668_at | -0.0817 | 0.6208 | |
| GSE45670 | MAN2C1 | 4123 | 203668_at | 0.0228 | 0.9123 | |
| GSE53622 | MAN2C1 | 4123 | 98112 | -0.1111 | 0.0654 | |
| GSE53624 | MAN2C1 | 4123 | 98112 | -0.1005 | 0.0879 | |
| GSE63941 | MAN2C1 | 4123 | 203668_at | 0.1124 | 0.8315 | |
| GSE77861 | MAN2C1 | 4123 | 203668_at | 0.2742 | 0.0984 | |
| GSE97050 | MAN2C1 | 4123 | A_23_P26117 | -0.2366 | 0.3094 | |
| SRP007169 | MAN2C1 | 4123 | RNAseq | -0.2948 | 0.4134 | |
| SRP008496 | MAN2C1 | 4123 | RNAseq | -0.4694 | 0.1036 | |
| SRP064894 | MAN2C1 | 4123 | RNAseq | 0.0662 | 0.6920 | |
| SRP133303 | MAN2C1 | 4123 | RNAseq | -0.3179 | 0.0782 | |
| SRP159526 | MAN2C1 | 4123 | RNAseq | 0.4797 | 0.1827 | |
| SRP193095 | MAN2C1 | 4123 | RNAseq | 0.2277 | 0.1039 | |
| SRP219564 | MAN2C1 | 4123 | RNAseq | 0.1556 | 0.6940 | |
| TCGA | MAN2C1 | 4123 | RNAseq | -0.1776 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAN2C1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAN2C1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAN2C1 | 4123 | 8 | 1 | 21 | |
| GSE20123 | MAN2C1 | 4123 | 8 | 1 | 21 | |
| GSE43470 | MAN2C1 | 4123 | 4 | 6 | 33 | |
| GSE46452 | MAN2C1 | 4123 | 3 | 7 | 49 | |
| GSE47630 | MAN2C1 | 4123 | 8 | 10 | 22 | |
| GSE54993 | MAN2C1 | 4123 | 5 | 6 | 59 | |
| GSE54994 | MAN2C1 | 4123 | 5 | 6 | 42 | |
| GSE60625 | MAN2C1 | 4123 | 4 | 0 | 7 | |
| GSE74703 | MAN2C1 | 4123 | 4 | 3 | 29 | |
| GSE74704 | MAN2C1 | 4123 | 4 | 1 | 15 | |
| TCGA | MAN2C1 | 4123 | 15 | 15 | 66 |
Total number of gains: 68; Total number of losses: 56; Total Number of normals: 364.
Somatic mutations of MAN2C1:
Generating mutation plots.
Highly correlated genes for MAN2C1:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAN2C1 | SHANK3 | 0.700274 | 4 | 0 | 4 |
| MAN2C1 | CTF1 | 0.684653 | 3 | 0 | 3 |
| MAN2C1 | MED9 | 0.641583 | 4 | 0 | 3 |
| MAN2C1 | PTPN9 | 0.63872 | 3 | 0 | 3 |
| MAN2C1 | JUNB | 0.631548 | 4 | 0 | 4 |
| MAN2C1 | ST5 | 0.627644 | 4 | 0 | 3 |
| MAN2C1 | RASD1 | 0.62746 | 3 | 0 | 3 |
| MAN2C1 | TPPP3 | 0.626295 | 3 | 0 | 3 |
| MAN2C1 | ROBO3 | 0.620457 | 3 | 0 | 3 |
| MAN2C1 | EGFL7 | 0.618425 | 4 | 0 | 3 |
| MAN2C1 | PTGES2 | 0.616273 | 3 | 0 | 3 |
| MAN2C1 | HDDC3 | 0.615781 | 3 | 0 | 3 |
| MAN2C1 | ABCB6 | 0.612653 | 3 | 0 | 3 |
| MAN2C1 | NAB2 | 0.612538 | 3 | 0 | 3 |
| MAN2C1 | MED15 | 0.607162 | 3 | 0 | 3 |
| MAN2C1 | CCDC84 | 0.604473 | 3 | 0 | 3 |
| MAN2C1 | SMG6 | 0.604304 | 4 | 0 | 3 |
| MAN2C1 | NOSTRIN | 0.602771 | 4 | 0 | 4 |
| MAN2C1 | AAAS | 0.601582 | 4 | 0 | 3 |
| MAN2C1 | NR4A1 | 0.600581 | 5 | 0 | 3 |
For details and further investigation, click here
