CCNB2

 

Full name: cyclin B2 Alias Symbol: HsT17299
Type: protein-coding gene Cytoband: 15q22.2
Entrez ID: 9133 HGNC ID: HGNC:1580 Ensembl Gene: ENSG00000157456 OMIM ID: 602755
Drug and gene relationship at DGIdb

 

CCNB2 involved pathways:

KEGG pathway Description View
hsa04068FoxO signaling pathway
hsa04110Cell cycle
hsa04114Oocyte meiosis
hsa04115p53 signaling pathway
hsa05166HTLV-I infection

 

Expression of CCNB2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCNB2 9133 202705_at 0.1925 0.9283
GSE20347 CCNB2 9133 202705_at 1.5815 0.0000
GSE23400 CCNB2 9133 202705_at 0.9899 0.0000
GSE26886 CCNB2 9133 202705_at 1.1387 0.0025
GSE29001 CCNB2 9133 202705_at 1.3820 0.0019
GSE38129 CCNB2 9133 202705_at 1.9902 0.0000
GSE45670 CCNB2 9133 202705_at 1.3128 0.0000
GSE53622 CCNB2 9133 81195 1.6437 0.0000
GSE53624 CCNB2 9133 81195 1.9278 0.0000
GSE63941 CCNB2 9133 202705_at 3.3444 0.0001
GSE77861 CCNB2 9133 202705_at 0.8352 0.0038
GSE97050 CCNB2 9133 A_23_P65757 1.1114 0.0860
SRP007169 CCNB2 9133 RNAseq 1.3978 0.0029
SRP008496 CCNB2 9133 RNAseq 1.0654 0.0011
SRP064894 CCNB2 9133 RNAseq 1.6250 0.0000
SRP133303 CCNB2 9133 RNAseq 1.4213 0.0000
SRP159526 CCNB2 9133 RNAseq 1.1840 0.0028
SRP193095 CCNB2 9133 RNAseq 0.9024 0.0000
SRP219564 CCNB2 9133 RNAseq 1.3100 0.0546
TCGA CCNB2 9133 RNAseq 1.3448 0.0000

Upregulated datasets: 14; Downregulated datasets: 0.  

 

Survival by CCNB2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCNB2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCNB2 9133 6 4 20
GSE20123 CCNB2 9133 6 3 21
GSE43470 CCNB2 9133 4 4 35
GSE46452 CCNB2 9133 3 7 49
GSE47630 CCNB2 9133 8 10 22
GSE54993 CCNB2 9133 5 6 59
GSE54994 CCNB2 9133 6 8 39
GSE60625 CCNB2 9133 4 0 7
GSE74703 CCNB2 9133 4 3 29
GSE74704 CCNB2 9133 2 3 15
TCGA CCNB2 9133 10 16 70

Total number of gains: 58; Total number of losses: 64; Total Number of normals: 366.  

 

Somatic mutations of CCNB2:

 

Generating mutation plots.

 

Highly correlated genes for CCNB2:

 

Showing top 20/1605 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCNB2UBE2C0.87756112012
CCNB2NUSAP10.87724612012
CCNB2BUB1B0.866922908
CCNB2KNSTRN0.861009606
CCNB2KIF230.85983512012
CCNB2TOP2A0.85630712012
CCNB2ASPM0.85547612012
CCNB2TPX20.85454312012
CCNB2RACGAP10.84876610010
CCNB2SPAG50.84771612012
CCNB2CDCA30.84625112012
CCNB2GINS10.8460611011
CCNB2CEP550.84391312012
CCNB2TTK0.84357612011
CCNB2DLGAP50.84353611011
CCNB2NEK20.84258612012
CCNB2PRC10.83910913012
CCNB2CENPN0.83692912012
CCNB2OIP50.835418909
CCNB2NUF20.835115808

For details and further investigation, click here