| Full name: annexin A3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.21 | ||
| Entrez ID: 306 | HGNC ID: HGNC:541 | Ensembl Gene: ENSG00000138772 | OMIM ID: 106490 |
| Drug and gene relationship at DGIdb | |||
Expression of ANXA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANXA3 | 306 | 209369_at | -1.7733 | 0.0642 | |
| GSE20347 | ANXA3 | 306 | 209369_at | -2.5086 | 0.0000 | |
| GSE23400 | ANXA3 | 306 | 209369_at | -1.1636 | 0.0000 | |
| GSE26886 | ANXA3 | 306 | 209369_at | -2.2288 | 0.0003 | |
| GSE29001 | ANXA3 | 306 | 209369_at | -1.7534 | 0.0051 | |
| GSE38129 | ANXA3 | 306 | 209369_at | -1.7575 | 0.0000 | |
| GSE45670 | ANXA3 | 306 | 209369_at | -1.0432 | 0.0084 | |
| GSE53622 | ANXA3 | 306 | 6484 | -1.3748 | 0.0000 | |
| GSE53624 | ANXA3 | 306 | 6484 | -1.5387 | 0.0000 | |
| GSE63941 | ANXA3 | 306 | 209369_at | 3.7023 | 0.0303 | |
| GSE77861 | ANXA3 | 306 | 209369_at | -1.9744 | 0.0242 | |
| GSE97050 | ANXA3 | 306 | A_23_P121716 | -0.7266 | 0.2251 | |
| SRP007169 | ANXA3 | 306 | RNAseq | -1.6812 | 0.0319 | |
| SRP008496 | ANXA3 | 306 | RNAseq | -2.0286 | 0.0030 | |
| SRP064894 | ANXA3 | 306 | RNAseq | -1.6646 | 0.0000 | |
| SRP133303 | ANXA3 | 306 | RNAseq | -1.2433 | 0.0000 | |
| SRP159526 | ANXA3 | 306 | RNAseq | -2.2536 | 0.0000 | |
| SRP193095 | ANXA3 | 306 | RNAseq | -1.4628 | 0.0000 | |
| SRP219564 | ANXA3 | 306 | RNAseq | -1.5165 | 0.0163 | |
| TCGA | ANXA3 | 306 | RNAseq | -0.4257 | 0.0053 |
Upregulated datasets: 1; Downregulated datasets: 16.
Survival by ANXA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANXA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANXA3 | 306 | 1 | 10 | 19 | |
| GSE20123 | ANXA3 | 306 | 1 | 10 | 19 | |
| GSE43470 | ANXA3 | 306 | 1 | 12 | 30 | |
| GSE46452 | ANXA3 | 306 | 1 | 36 | 22 | |
| GSE47630 | ANXA3 | 306 | 1 | 19 | 20 | |
| GSE54993 | ANXA3 | 306 | 8 | 0 | 62 | |
| GSE54994 | ANXA3 | 306 | 0 | 9 | 44 | |
| GSE60625 | ANXA3 | 306 | 0 | 0 | 11 | |
| GSE74703 | ANXA3 | 306 | 1 | 10 | 25 | |
| GSE74704 | ANXA3 | 306 | 1 | 6 | 13 | |
| TCGA | ANXA3 | 306 | 13 | 32 | 51 |
Total number of gains: 28; Total number of losses: 144; Total Number of normals: 316.
Somatic mutations of ANXA3:
Generating mutation plots.
Highly correlated genes for ANXA3:
Showing top 20/1001 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANXA3 | ZNF514 | 0.746983 | 3 | 0 | 3 |
| ANXA3 | PDIK1L | 0.721618 | 3 | 0 | 3 |
| ANXA3 | SPAG17 | 0.71635 | 3 | 0 | 3 |
| ANXA3 | AP3M1 | 0.708908 | 3 | 0 | 3 |
| ANXA3 | UQCR10 | 0.696164 | 3 | 0 | 3 |
| ANXA3 | KDM3B | 0.69389 | 3 | 0 | 3 |
| ANXA3 | SGMS2 | 0.693862 | 7 | 0 | 6 |
| ANXA3 | RNF185 | 0.691045 | 4 | 0 | 3 |
| ANXA3 | SLC25A27 | 0.690269 | 3 | 0 | 3 |
| ANXA3 | CWH43 | 0.690052 | 10 | 0 | 10 |
| ANXA3 | HIGD1A | 0.689927 | 11 | 0 | 11 |
| ANXA3 | PDLIM5 | 0.688912 | 11 | 0 | 11 |
| ANXA3 | PPP1R3B | 0.685926 | 7 | 0 | 7 |
| ANXA3 | CCDC28A | 0.685244 | 3 | 0 | 3 |
| ANXA3 | PITHD1 | 0.684625 | 5 | 0 | 5 |
| ANXA3 | ACP6 | 0.684239 | 3 | 0 | 3 |
| ANXA3 | GANC | 0.683383 | 6 | 0 | 6 |
| ANXA3 | E2F8 | 0.681007 | 4 | 0 | 3 |
| ANXA3 | RAB11A | 0.680875 | 12 | 0 | 12 |
| ANXA3 | FCHO2 | 0.680327 | 7 | 0 | 7 |
For details and further investigation, click here
