| Full name: methyltransferase like 21A | Alias Symbol: LOC151194|HCA557b|HSPA-KMT | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 151194 | HGNC ID: HGNC:30476 | Ensembl Gene: ENSG00000144401 | OMIM ID: 615257 |
| Drug and gene relationship at DGIdb | |||
Expression of METTL21A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL21A | 151194 | 235177_at | 0.1572 | 0.8680 | |
| GSE26886 | METTL21A | 151194 | 235177_at | 0.6893 | 0.0235 | |
| GSE45670 | METTL21A | 151194 | 235177_at | 0.6297 | 0.0020 | |
| GSE53622 | METTL21A | 151194 | 51273 | 0.3714 | 0.0003 | |
| GSE53624 | METTL21A | 151194 | 51273 | 0.3412 | 0.0002 | |
| GSE63941 | METTL21A | 151194 | 235177_at | 0.1977 | 0.7517 | |
| GSE77861 | METTL21A | 151194 | 235177_at | 0.5393 | 0.0367 | |
| GSE97050 | METTL21A | 151194 | A_23_P156809 | 1.0976 | 0.0556 | |
| SRP007169 | METTL21A | 151194 | RNAseq | 1.2105 | 0.0026 | |
| SRP008496 | METTL21A | 151194 | RNAseq | 1.5239 | 0.0000 | |
| SRP064894 | METTL21A | 151194 | RNAseq | 1.3402 | 0.0000 | |
| SRP133303 | METTL21A | 151194 | RNAseq | 0.3483 | 0.0168 | |
| SRP159526 | METTL21A | 151194 | RNAseq | 2.2287 | 0.0000 | |
| SRP193095 | METTL21A | 151194 | RNAseq | 0.7841 | 0.0000 | |
| SRP219564 | METTL21A | 151194 | RNAseq | 0.6467 | 0.0300 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by METTL21A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of METTL21A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL21A | 151194 | 3 | 7 | 20 | |
| GSE20123 | METTL21A | 151194 | 3 | 7 | 20 | |
| GSE43470 | METTL21A | 151194 | 2 | 4 | 37 | |
| GSE46452 | METTL21A | 151194 | 1 | 4 | 54 | |
| GSE47630 | METTL21A | 151194 | 4 | 5 | 31 | |
| GSE54993 | METTL21A | 151194 | 0 | 3 | 67 | |
| GSE54994 | METTL21A | 151194 | 8 | 9 | 36 | |
| GSE60625 | METTL21A | 151194 | 0 | 3 | 8 | |
| GSE74703 | METTL21A | 151194 | 2 | 3 | 31 | |
| GSE74704 | METTL21A | 151194 | 2 | 3 | 15 | |
| TCGA | METTL21A | 151194 | 15 | 21 | 60 |
Total number of gains: 40; Total number of losses: 69; Total Number of normals: 379.
Somatic mutations of METTL21A:
Generating mutation plots.
Highly correlated genes for METTL21A:
Showing top 20/206 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL21A | C12orf66 | 0.658454 | 3 | 0 | 3 |
| METTL21A | KRTCAP3 | 0.642281 | 4 | 0 | 3 |
| METTL21A | MBTPS2 | 0.634724 | 3 | 0 | 3 |
| METTL21A | PRMT6 | 0.632242 | 3 | 0 | 3 |
| METTL21A | CDC25A | 0.624669 | 4 | 0 | 4 |
| METTL21A | AHR | 0.62355 | 3 | 0 | 3 |
| METTL21A | UXS1 | 0.620939 | 4 | 0 | 4 |
| METTL21A | SPAST | 0.619215 | 4 | 0 | 3 |
| METTL21A | GAS2L1 | 0.618264 | 3 | 0 | 3 |
| METTL21A | SEC11A | 0.618214 | 4 | 0 | 3 |
| METTL21A | CEP152 | 0.6153 | 3 | 0 | 3 |
| METTL21A | TRAF4 | 0.611537 | 4 | 0 | 3 |
| METTL21A | NUP205 | 0.607374 | 4 | 0 | 3 |
| METTL21A | EME1 | 0.605301 | 4 | 0 | 4 |
| METTL21A | ZKSCAN5 | 0.603976 | 4 | 0 | 4 |
| METTL21A | LRRC57 | 0.598814 | 4 | 0 | 3 |
| METTL21A | ATIC | 0.598269 | 5 | 0 | 4 |
| METTL21A | WDR12 | 0.595487 | 5 | 0 | 4 |
| METTL21A | SFT2D3 | 0.594232 | 3 | 0 | 3 |
| METTL21A | RTN4IP1 | 0.593488 | 5 | 0 | 4 |
For details and further investigation, click here
