| Full name: G protein-coupled receptor class C group 5 member A | Alias Symbol: RAIG1|TIG1|PEIG-1 | ||
| Type: protein-coding gene | Cytoband: 12p13.1 | ||
| Entrez ID: 9052 | HGNC ID: HGNC:9836 | Ensembl Gene: ENSG00000013588 | OMIM ID: 604138 |
| Drug and gene relationship at DGIdb | |||
Expression of GPRC5A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPRC5A | 9052 | 203108_at | -0.9848 | 0.3538 | |
| GSE20347 | GPRC5A | 9052 | 203108_at | -1.0796 | 0.0143 | |
| GSE23400 | GPRC5A | 9052 | 203108_at | -0.8573 | 0.0000 | |
| GSE26886 | GPRC5A | 9052 | 203108_at | -1.2200 | 0.0338 | |
| GSE29001 | GPRC5A | 9052 | 212444_at | -0.0735 | 0.9279 | |
| GSE38129 | GPRC5A | 9052 | 203108_at | -0.7553 | 0.0861 | |
| GSE45670 | GPRC5A | 9052 | 203108_at | 1.0615 | 0.0287 | |
| GSE53622 | GPRC5A | 9052 | 19473 | -0.2159 | 0.2118 | |
| GSE53624 | GPRC5A | 9052 | 19473 | -0.6982 | 0.0000 | |
| GSE63941 | GPRC5A | 9052 | 203108_at | 0.5627 | 0.7879 | |
| GSE77861 | GPRC5A | 9052 | 203108_at | -0.4511 | 0.3064 | |
| GSE97050 | GPRC5A | 9052 | A_23_P36825 | 0.6992 | 0.4033 | |
| SRP007169 | GPRC5A | 9052 | RNAseq | -2.7844 | 0.0018 | |
| SRP008496 | GPRC5A | 9052 | RNAseq | -2.3375 | 0.0055 | |
| SRP064894 | GPRC5A | 9052 | RNAseq | -1.9792 | 0.0000 | |
| SRP133303 | GPRC5A | 9052 | RNAseq | 0.6641 | 0.0292 | |
| SRP159526 | GPRC5A | 9052 | RNAseq | -2.0495 | 0.0000 | |
| SRP193095 | GPRC5A | 9052 | RNAseq | -0.6474 | 0.0346 | |
| SRP219564 | GPRC5A | 9052 | RNAseq | -0.4656 | 0.4995 | |
| TCGA | GPRC5A | 9052 | RNAseq | -0.1607 | 0.3657 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by GPRC5A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPRC5A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPRC5A | 9052 | 6 | 2 | 22 | |
| GSE20123 | GPRC5A | 9052 | 6 | 2 | 22 | |
| GSE43470 | GPRC5A | 9052 | 10 | 4 | 29 | |
| GSE46452 | GPRC5A | 9052 | 10 | 1 | 48 | |
| GSE47630 | GPRC5A | 9052 | 13 | 2 | 25 | |
| GSE54993 | GPRC5A | 9052 | 2 | 9 | 59 | |
| GSE54994 | GPRC5A | 9052 | 10 | 2 | 41 | |
| GSE60625 | GPRC5A | 9052 | 0 | 1 | 10 | |
| GSE74703 | GPRC5A | 9052 | 9 | 3 | 24 | |
| GSE74704 | GPRC5A | 9052 | 4 | 1 | 15 | |
| TCGA | GPRC5A | 9052 | 39 | 7 | 50 |
Total number of gains: 109; Total number of losses: 34; Total Number of normals: 345.
Somatic mutations of GPRC5A:
Generating mutation plots.
Highly correlated genes for GPRC5A:
Showing top 20/305 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPRC5A | VTA1 | 0.656452 | 3 | 0 | 3 |
| GPRC5A | SERBP1 | 0.647738 | 3 | 0 | 3 |
| GPRC5A | RNF141 | 0.634419 | 6 | 0 | 5 |
| GPRC5A | RAB11A | 0.631002 | 6 | 0 | 5 |
| GPRC5A | FAM107B | 0.62943 | 3 | 0 | 3 |
| GPRC5A | RALA | 0.620682 | 6 | 0 | 4 |
| GPRC5A | RASSF1 | 0.616175 | 3 | 0 | 3 |
| GPRC5A | PDCD6IP | 0.614168 | 7 | 0 | 5 |
| GPRC5A | SRPX2 | 0.607566 | 9 | 0 | 6 |
| GPRC5A | MIR34A | 0.600617 | 3 | 0 | 3 |
| GPRC5A | TMED3 | 0.597221 | 7 | 0 | 5 |
| GPRC5A | CLPX | 0.597163 | 6 | 0 | 3 |
| GPRC5A | TRIM6 | 0.596771 | 4 | 0 | 3 |
| GPRC5A | VAV3 | 0.596371 | 7 | 0 | 6 |
| GPRC5A | HCAR3 | 0.596295 | 6 | 0 | 4 |
| GPRC5A | KRT7 | 0.592992 | 5 | 0 | 4 |
| GPRC5A | C19orf33 | 0.58895 | 5 | 0 | 3 |
| GPRC5A | S100A2 | 0.588593 | 7 | 0 | 4 |
| GPRC5A | CLIC3 | 0.588192 | 8 | 0 | 6 |
| GPRC5A | HS3ST1 | 0.586657 | 7 | 0 | 5 |
For details and further investigation, click here
