| Full name: matrix metallopeptidase 20 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q22.2 | ||
| Entrez ID: 9313 | HGNC ID: HGNC:7167 | Ensembl Gene: ENSG00000137674 | OMIM ID: 604629 |
| Drug and gene relationship at DGIdb | |||
Expression of MMP20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MMP20 | 9313 | 207599_at | 0.0431 | 0.8186 | |
| GSE20347 | MMP20 | 9313 | 207599_at | 0.3739 | 0.2335 | |
| GSE23400 | MMP20 | 9313 | 207599_at | 0.0309 | 0.3932 | |
| GSE26886 | MMP20 | 9313 | 207599_at | 0.4964 | 0.1006 | |
| GSE29001 | MMP20 | 9313 | 207599_at | 0.1394 | 0.2537 | |
| GSE38129 | MMP20 | 9313 | 207599_at | 0.2234 | 0.2837 | |
| GSE45670 | MMP20 | 9313 | 207599_at | 0.2489 | 0.5728 | |
| GSE53622 | MMP20 | 9313 | 68259 | 1.4188 | 0.0000 | |
| GSE53624 | MMP20 | 9313 | 68259 | 0.4816 | 0.0060 | |
| GSE63941 | MMP20 | 9313 | 207599_at | 0.0459 | 0.8040 | |
| GSE77861 | MMP20 | 9313 | 207599_at | -0.0295 | 0.7052 | |
| TCGA | MMP20 | 9313 | RNAseq | 3.4466 | 0.0409 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MMP20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MMP20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MMP20 | 9313 | 5 | 8 | 17 | |
| GSE20123 | MMP20 | 9313 | 5 | 8 | 17 | |
| GSE43470 | MMP20 | 9313 | 6 | 5 | 32 | |
| GSE46452 | MMP20 | 9313 | 5 | 24 | 30 | |
| GSE47630 | MMP20 | 9313 | 2 | 19 | 19 | |
| GSE54993 | MMP20 | 9313 | 9 | 2 | 59 | |
| GSE54994 | MMP20 | 9313 | 6 | 18 | 29 | |
| GSE60625 | MMP20 | 9313 | 0 | 3 | 8 | |
| GSE74703 | MMP20 | 9313 | 4 | 4 | 28 | |
| GSE74704 | MMP20 | 9313 | 5 | 4 | 11 | |
| TCGA | MMP20 | 9313 | 10 | 44 | 42 |
Total number of gains: 57; Total number of losses: 139; Total Number of normals: 292.
Somatic mutations of MMP20:
Generating mutation plots.
Highly correlated genes for MMP20:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MMP20 | SMIM8 | 0.648566 | 3 | 0 | 3 |
| MMP20 | CCR3 | 0.612131 | 3 | 0 | 3 |
| MMP20 | CHGB | 0.610106 | 3 | 0 | 3 |
| MMP20 | SLCO1A2 | 0.604711 | 4 | 0 | 3 |
| MMP20 | VTCN1 | 0.600734 | 3 | 0 | 3 |
| MMP20 | COL9A3 | 0.586828 | 3 | 0 | 3 |
| MMP20 | SOX11 | 0.579379 | 4 | 0 | 3 |
| MMP20 | SEMA4C | 0.573864 | 4 | 0 | 3 |
| MMP20 | CCDC148 | 0.573361 | 3 | 0 | 3 |
| MMP20 | TRPC3 | 0.572386 | 3 | 0 | 3 |
| MMP20 | ARSB | 0.567503 | 4 | 0 | 3 |
| MMP20 | POMGNT2 | 0.558012 | 3 | 0 | 3 |
| MMP20 | KRT86 | 0.552144 | 5 | 0 | 3 |
| MMP20 | HPCAL1 | 0.543334 | 3 | 0 | 3 |
| MMP20 | GLIPR1 | 0.54087 | 4 | 0 | 3 |
| MMP20 | HRG | 0.537226 | 4 | 0 | 3 |
| MMP20 | ASXL1 | 0.534587 | 4 | 0 | 3 |
| MMP20 | MYT1L | 0.525234 | 3 | 0 | 3 |
| MMP20 | BIRC2 | 0.524428 | 7 | 0 | 4 |
| MMP20 | CHRNB3 | 0.518966 | 4 | 0 | 3 |
For details and further investigation, click here
