MOB1A

 

Full name: MOB kinase activator 1A Alias Symbol: FLJ10788|MOB1|FLJ11595|Mob4B|Mats1
Type: protein-coding gene Cytoband: 2p13.1
Entrez ID: 55233 HGNC ID: HGNC:16015 Ensembl Gene: ENSG00000114978 OMIM ID: 609281

 

MOB1A involved pathways:

KEGG pathway Description View
hsa04390Hippo signaling pathway

 

Expression of MOB1A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MOB1A 55233 214812_s_at 0.3414 0.3815
GSE20347 MOB1A 55233 214812_s_at 0.1164 0.3539
GSE23400 MOB1A 55233 214812_s_at 0.3243 0.0000
GSE26886 MOB1A 55233 214812_s_at -0.0836 0.6750
GSE29001 MOB1A 55233 214812_s_at 0.2438 0.2998
GSE38129 MOB1A 55233 214812_s_at 0.2218 0.0201
GSE45670 MOB1A 55233 201298_s_at 0.2980 0.0277
GSE53622 MOB1A 55233 17548 0.3360 0.0000
GSE53624 MOB1A 55233 17548 0.0800 0.2113
GSE63941 MOB1A 55233 201298_s_at 1.4130 0.0006
GSE77861 MOB1A 55233 214812_s_at 0.3318 0.1138
GSE97050 MOB1A 55233 A_24_P379765 0.2565 0.3463
SRP007169 MOB1A 55233 RNAseq 0.0762 0.8073
SRP008496 MOB1A 55233 RNAseq 0.2574 0.1674
SRP064894 MOB1A 55233 RNAseq 0.0820 0.5834
SRP133303 MOB1A 55233 RNAseq 0.5955 0.0000
SRP159526 MOB1A 55233 RNAseq 0.0864 0.6531
SRP193095 MOB1A 55233 RNAseq 0.0063 0.9524
SRP219564 MOB1A 55233 RNAseq -0.0798 0.7197

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by MOB1A expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of MOB1A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MOB1A 55233 10 1 19
GSE20123 MOB1A 55233 11 1 18
GSE43470 MOB1A 55233 4 0 39
GSE46452 MOB1A 55233 2 3 54
GSE47630 MOB1A 55233 7 0 33
GSE54993 MOB1A 55233 0 6 64
GSE54994 MOB1A 55233 10 0 43
GSE60625 MOB1A 55233 0 3 8
GSE74703 MOB1A 55233 4 0 32
GSE74704 MOB1A 55233 8 0 12
TCGA MOB1A 55233 38 2 56

Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.  

 

Somatic mutations of MOB1A:

 

Generating mutation plots.

 

Highly correlated genes for MOB1A:

 

Showing top 20/966 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MOB1AMRPL380.738308303
MOB1ATRAPPC10.712607303
MOB1ADGUOK0.70289310010
MOB1APRMT60.702094303
MOB1APIGH0.693502303
MOB1AKLHL130.688198403
MOB1AMRPS50.682774303
MOB1ACTNNBL10.679167303
MOB1AZFPL10.678761404
MOB1APTGFRN0.678185404
MOB1ASORD0.678057303
MOB1ARBMX20.67499303
MOB1ASFT2D30.67316403
MOB1APTGES20.669733404
MOB1AUBE2L30.669373303
MOB1ALSM100.669075303
MOB1AITPA0.66745303
MOB1ARNF260.666364403
MOB1ARIOK20.665856303
MOB1APIF10.665129404

For details and further investigation, click here