| Full name: PIH1 domain containing 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.1 | ||
| Entrez ID: 120379 | HGNC ID: HGNC:25210 | Ensembl Gene: ENSG00000150773 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PIH1D2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIH1D2 | 120379 | 235062_at | -0.3109 | 0.3617 | |
| GSE26886 | PIH1D2 | 120379 | 235062_at | -0.1699 | 0.4117 | |
| GSE45670 | PIH1D2 | 120379 | 235062_at | -0.6627 | 0.0014 | |
| GSE53622 | PIH1D2 | 120379 | 54632 | 0.4282 | 0.0032 | |
| GSE53624 | PIH1D2 | 120379 | 54632 | -0.3261 | 0.0035 | |
| GSE63941 | PIH1D2 | 120379 | 235062_at | 0.0034 | 0.9911 | |
| GSE77861 | PIH1D2 | 120379 | 235062_at | -0.3600 | 0.0277 | |
| GSE97050 | PIH1D2 | 120379 | A_33_P3278058 | -0.1842 | 0.4706 | |
| SRP064894 | PIH1D2 | 120379 | RNAseq | -1.4290 | 0.0000 | |
| SRP133303 | PIH1D2 | 120379 | RNAseq | -0.8874 | 0.0046 | |
| SRP159526 | PIH1D2 | 120379 | RNAseq | -0.6344 | 0.0882 | |
| SRP193095 | PIH1D2 | 120379 | RNAseq | -1.6423 | 0.0000 | |
| SRP219564 | PIH1D2 | 120379 | RNAseq | -1.7371 | 0.0003 | |
| TCGA | PIH1D2 | 120379 | RNAseq | 0.0127 | 0.9485 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by PIH1D2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIH1D2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIH1D2 | 120379 | 0 | 12 | 18 | |
| GSE20123 | PIH1D2 | 120379 | 0 | 12 | 18 | |
| GSE43470 | PIH1D2 | 120379 | 2 | 6 | 35 | |
| GSE46452 | PIH1D2 | 120379 | 3 | 26 | 30 | |
| GSE47630 | PIH1D2 | 120379 | 2 | 19 | 19 | |
| GSE54993 | PIH1D2 | 120379 | 10 | 0 | 60 | |
| GSE54994 | PIH1D2 | 120379 | 5 | 19 | 29 | |
| GSE60625 | PIH1D2 | 120379 | 0 | 3 | 8 | |
| GSE74703 | PIH1D2 | 120379 | 1 | 4 | 31 | |
| GSE74704 | PIH1D2 | 120379 | 0 | 8 | 12 | |
| TCGA | PIH1D2 | 120379 | 7 | 48 | 41 |
Total number of gains: 30; Total number of losses: 157; Total Number of normals: 301.
Somatic mutations of PIH1D2:
Generating mutation plots.
Highly correlated genes for PIH1D2:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIH1D2 | UBL3 | 0.78911 | 3 | 0 | 3 |
| PIH1D2 | MMEL1 | 0.782915 | 3 | 0 | 3 |
| PIH1D2 | ATP6V1C2 | 0.767757 | 3 | 0 | 3 |
| PIH1D2 | PDLIM5 | 0.757643 | 3 | 0 | 3 |
| PIH1D2 | SERAC1 | 0.754111 | 3 | 0 | 3 |
| PIH1D2 | BLNK | 0.745326 | 3 | 0 | 3 |
| PIH1D2 | PADI1 | 0.743906 | 3 | 0 | 3 |
| PIH1D2 | LAMTOR3 | 0.742882 | 3 | 0 | 3 |
| PIH1D2 | EPB41L3 | 0.741092 | 3 | 0 | 3 |
| PIH1D2 | RALA | 0.738969 | 3 | 0 | 3 |
| PIH1D2 | CUL3 | 0.738308 | 3 | 0 | 3 |
| PIH1D2 | SASH1 | 0.737647 | 3 | 0 | 3 |
| PIH1D2 | PRKAB1 | 0.737476 | 3 | 0 | 3 |
| PIH1D2 | TRIP10 | 0.736247 | 3 | 0 | 3 |
| PIH1D2 | MRPS18C | 0.733191 | 3 | 0 | 3 |
| PIH1D2 | GAB2 | 0.730914 | 3 | 0 | 3 |
| PIH1D2 | SHROOM3 | 0.730309 | 3 | 0 | 3 |
| PIH1D2 | RUSC2 | 0.727233 | 3 | 0 | 3 |
| PIH1D2 | ARHGEF10L | 0.719321 | 3 | 0 | 3 |
| PIH1D2 | C18orf25 | 0.718941 | 4 | 0 | 3 |
For details and further investigation, click here
