| Full name: forkhead box N1 | Alias Symbol: FKHL20 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 8456 | HGNC ID: HGNC:12765 | Ensembl Gene: ENSG00000109101 | OMIM ID: 600838 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXN1 | 8456 | 1558687_a_at | -0.1468 | 0.8659 | |
| GSE20347 | FOXN1 | 8456 | 207683_at | -0.3250 | 0.0000 | |
| GSE23400 | FOXN1 | 8456 | 207683_at | -0.1670 | 0.0015 | |
| GSE26886 | FOXN1 | 8456 | 1558687_a_at | -2.0626 | 0.0005 | |
| GSE29001 | FOXN1 | 8456 | 207683_at | -0.1585 | 0.3095 | |
| GSE38129 | FOXN1 | 8456 | 207683_at | -0.2567 | 0.0158 | |
| GSE45670 | FOXN1 | 8456 | 1558687_a_at | 0.3173 | 0.3429 | |
| GSE53622 | FOXN1 | 8456 | 92870 | -0.0015 | 0.9906 | |
| GSE53624 | FOXN1 | 8456 | 92870 | 0.0482 | 0.4281 | |
| GSE63941 | FOXN1 | 8456 | 1558687_a_at | 0.6421 | 0.4627 | |
| GSE77861 | FOXN1 | 8456 | 1558687_a_at | -0.0586 | 0.9581 | |
| GSE97050 | FOXN1 | 8456 | A_23_P118693 | 0.1130 | 0.7497 | |
| SRP007169 | FOXN1 | 8456 | RNAseq | -1.7331 | 0.0001 | |
| SRP008496 | FOXN1 | 8456 | RNAseq | -1.8887 | 0.0001 | |
| SRP064894 | FOXN1 | 8456 | RNAseq | -0.7214 | 0.1228 | |
| SRP133303 | FOXN1 | 8456 | RNAseq | -1.5835 | 0.0000 | |
| SRP159526 | FOXN1 | 8456 | RNAseq | -0.5914 | 0.5378 | |
| SRP219564 | FOXN1 | 8456 | RNAseq | -1.7247 | 0.1244 | |
| TCGA | FOXN1 | 8456 | RNAseq | 1.4668 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by FOXN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXN1 | 8456 | 9 | 1 | 20 | |
| GSE20123 | FOXN1 | 8456 | 9 | 1 | 20 | |
| GSE43470 | FOXN1 | 8456 | 0 | 1 | 42 | |
| GSE46452 | FOXN1 | 8456 | 33 | 1 | 25 | |
| GSE47630 | FOXN1 | 8456 | 7 | 1 | 32 | |
| GSE54993 | FOXN1 | 8456 | 2 | 3 | 65 | |
| GSE54994 | FOXN1 | 8456 | 7 | 6 | 40 | |
| GSE60625 | FOXN1 | 8456 | 4 | 0 | 7 | |
| GSE74703 | FOXN1 | 8456 | 0 | 1 | 35 | |
| GSE74704 | FOXN1 | 8456 | 7 | 1 | 12 | |
| TCGA | FOXN1 | 8456 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of FOXN1:
Generating mutation plots.
Highly correlated genes for FOXN1:
Showing top 20/689 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXN1 | MTA3 | 0.728502 | 3 | 0 | 3 |
| FOXN1 | WNK1 | 0.714943 | 3 | 0 | 3 |
| FOXN1 | GNG4 | 0.702751 | 3 | 0 | 3 |
| FOXN1 | HPX | 0.695543 | 4 | 0 | 4 |
| FOXN1 | CER1 | 0.690986 | 3 | 0 | 3 |
| FOXN1 | MAL2 | 0.689923 | 3 | 0 | 3 |
| FOXN1 | CCIN | 0.687258 | 4 | 0 | 4 |
| FOXN1 | LIN7C | 0.672258 | 3 | 0 | 3 |
| FOXN1 | TOM1L2 | 0.665808 | 5 | 0 | 5 |
| FOXN1 | FBXO3 | 0.66194 | 3 | 0 | 3 |
| FOXN1 | CRYBB1 | 0.661855 | 4 | 0 | 4 |
| FOXN1 | GJA8 | 0.658176 | 3 | 0 | 3 |
| FOXN1 | NR6A1 | 0.653247 | 4 | 0 | 4 |
| FOXN1 | MASP2 | 0.651891 | 4 | 0 | 4 |
| FOXN1 | IRF2BP1 | 0.651822 | 4 | 0 | 4 |
| FOXN1 | KCNJ6 | 0.651111 | 5 | 0 | 5 |
| FOXN1 | GJB6 | 0.650776 | 6 | 0 | 5 |
| FOXN1 | CSNK1A1 | 0.648661 | 3 | 0 | 3 |
| FOXN1 | PNPLA2 | 0.647777 | 3 | 0 | 3 |
| FOXN1 | POU2F2 | 0.644214 | 4 | 0 | 4 |
For details and further investigation, click here
