| Full name: myosin binding protein C, fast type | Alias Symbol: MYBPCF|MYBPC|MGC163408|fsMyBP-C | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 4606 | HGNC ID: HGNC:7550 | Ensembl Gene: ENSG00000086967 | OMIM ID: 160793 |
| Drug and gene relationship at DGIdb | |||
Expression of MYBPC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYBPC2 | 4606 | 206394_at | -0.1104 | 0.7346 | |
| GSE20347 | MYBPC2 | 4606 | 206394_at | -0.0104 | 0.8932 | |
| GSE23400 | MYBPC2 | 4606 | 206394_at | -0.1174 | 0.0371 | |
| GSE26886 | MYBPC2 | 4606 | 206394_at | 0.1500 | 0.4364 | |
| GSE29001 | MYBPC2 | 4606 | 206394_at | 0.0133 | 0.9217 | |
| GSE38129 | MYBPC2 | 4606 | 206394_at | -0.0860 | 0.1567 | |
| GSE45670 | MYBPC2 | 4606 | 206394_at | 0.0860 | 0.3430 | |
| GSE53622 | MYBPC2 | 4606 | 22710 | -0.7942 | 0.0000 | |
| GSE53624 | MYBPC2 | 4606 | 22710 | -1.4778 | 0.0000 | |
| GSE63941 | MYBPC2 | 4606 | 206394_at | 0.1174 | 0.5427 | |
| GSE77861 | MYBPC2 | 4606 | 206394_at | -0.1605 | 0.0586 | |
| TCGA | MYBPC2 | 4606 | RNAseq | 1.0024 | 0.3335 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MYBPC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYBPC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYBPC2 | 4606 | 3 | 4 | 23 | |
| GSE20123 | MYBPC2 | 4606 | 3 | 3 | 24 | |
| GSE43470 | MYBPC2 | 4606 | 4 | 11 | 28 | |
| GSE46452 | MYBPC2 | 4606 | 45 | 1 | 13 | |
| GSE47630 | MYBPC2 | 4606 | 9 | 6 | 25 | |
| GSE54993 | MYBPC2 | 4606 | 17 | 4 | 49 | |
| GSE54994 | MYBPC2 | 4606 | 4 | 14 | 35 | |
| GSE60625 | MYBPC2 | 4606 | 9 | 0 | 2 | |
| GSE74703 | MYBPC2 | 4606 | 4 | 7 | 25 | |
| GSE74704 | MYBPC2 | 4606 | 3 | 1 | 16 | |
| TCGA | MYBPC2 | 4606 | 14 | 19 | 63 |
Total number of gains: 115; Total number of losses: 70; Total Number of normals: 303.
Somatic mutations of MYBPC2:
Generating mutation plots.
Highly correlated genes for MYBPC2:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYBPC2 | KCNG2 | 0.675498 | 3 | 0 | 3 |
| MYBPC2 | BCL2L15 | 0.623363 | 4 | 0 | 3 |
| MYBPC2 | CITED1 | 0.619433 | 4 | 0 | 3 |
| MYBPC2 | APOA2 | 0.61683 | 3 | 0 | 3 |
| MYBPC2 | CLEC10A | 0.600515 | 4 | 0 | 4 |
| MYBPC2 | TMED3 | 0.569357 | 4 | 0 | 3 |
| MYBPC2 | ALX3 | 0.568361 | 3 | 0 | 3 |
| MYBPC2 | ARSF | 0.564995 | 4 | 0 | 3 |
| MYBPC2 | TSSK2 | 0.557469 | 4 | 0 | 3 |
| MYBPC2 | TLR7 | 0.556484 | 5 | 0 | 3 |
| MYBPC2 | ADAMTS13 | 0.55629 | 5 | 0 | 3 |
| MYBPC2 | C14orf180 | 0.556262 | 4 | 0 | 3 |
| MYBPC2 | GIP | 0.554769 | 3 | 0 | 3 |
| MYBPC2 | PPP3CC | 0.554205 | 3 | 0 | 3 |
| MYBPC2 | LRBA | 0.552142 | 4 | 0 | 3 |
| MYBPC2 | MASP1 | 0.549981 | 4 | 0 | 3 |
| MYBPC2 | ZNF536 | 0.549053 | 5 | 0 | 3 |
| MYBPC2 | FAM155A | 0.548244 | 5 | 0 | 3 |
| MYBPC2 | SPNS3 | 0.547103 | 4 | 0 | 3 |
| MYBPC2 | AKAP7 | 0.546844 | 4 | 0 | 3 |
For details and further investigation, click here
