MYO5C

 

Full name: myosin VC Alias Symbol: MGC74969
Type: protein-coding gene Cytoband: 15q21.2
Entrez ID: 55930 HGNC ID: HGNC:7604 Ensembl Gene: ENSG00000128833 OMIM ID: 610022
Drug and gene relationship at DGIdb

 

Expression of MYO5C:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MYO5C 55930 218966_at -1.5069 0.0383
GSE20347 MYO5C 55930 218966_at -1.1177 0.0001
GSE23400 MYO5C 55930 218966_at -0.5892 0.0000
GSE26886 MYO5C 55930 218966_at -1.5200 0.0058
GSE29001 MYO5C 55930 218966_at -1.1208 0.0383
GSE38129 MYO5C 55930 218966_at -0.8895 0.0001
GSE45670 MYO5C 55930 218966_at -1.1525 0.0027
GSE53622 MYO5C 55930 152927 -1.3452 0.0000
GSE53624 MYO5C 55930 100589 -1.9145 0.0000
GSE63941 MYO5C 55930 218966_at 3.7330 0.0159
GSE77861 MYO5C 55930 218966_at -0.4979 0.2570
GSE97050 MYO5C 55930 A_33_P3361037 0.1706 0.5480
SRP007169 MYO5C 55930 RNAseq 0.5213 0.3627
SRP064894 MYO5C 55930 RNAseq -1.3394 0.0001
SRP133303 MYO5C 55930 RNAseq -1.0476 0.0082
SRP159526 MYO5C 55930 RNAseq -1.1607 0.0002
SRP193095 MYO5C 55930 RNAseq -0.7617 0.0155
SRP219564 MYO5C 55930 RNAseq -0.9550 0.1432
TCGA MYO5C 55930 RNAseq -0.7746 0.0000

Upregulated datasets: 1; Downregulated datasets: 10.  


 

Survival by MYO5C expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MYO5C:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MYO5C 55930 5 4 21
GSE20123 MYO5C 55930 5 4 21
GSE43470 MYO5C 55930 4 3 36
GSE46452 MYO5C 55930 3 7 49
GSE47630 MYO5C 55930 8 10 22
GSE54993 MYO5C 55930 5 6 59
GSE54994 MYO5C 55930 5 7 41
GSE60625 MYO5C 55930 4 0 7
GSE74703 MYO5C 55930 4 2 30
GSE74704 MYO5C 55930 2 3 15
TCGA MYO5C 55930 9 17 70

Total number of gains: 54; Total number of losses: 63; Total Number of normals: 371.  


 

Somatic mutations of MYO5C:

 

Generating mutation plots.

 

Highly correlated genes for MYO5C:

 

Showing top 20/895 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MYO5CARHGEF70.764368303
MYO5CTMEM2180.734181303
MYO5CUTY0.7233303
MYO5CZNF1800.722777303
MYO5CSVIP0.722135707
MYO5CFAM122A0.718979303
MYO5CSPRYD40.717377303
MYO5CFBXL30.707262403
MYO5CUSP540.705766808
MYO5COS90.701859404
MYO5CPTPRB0.700695303
MYO5CSPATA180.692622606
MYO5CCCL220.692209303
MYO5CECHDC20.69192811011
MYO5CSHROOM30.684398606
MYO5CPPFIBP20.68378711010
MYO5CNOA10.683297303
MYO5CYPEL30.682827606
MYO5CEYA20.68150311011
MYO5CPPM1L0.669432606

For details and further investigation, click here