| Full name: NAD kinase 2, mitochondrial | Alias Symbol: FLJ30596|MNADK | ||
| Type: protein-coding gene | Cytoband: 5p13.2 | ||
| Entrez ID: 133686 | HGNC ID: HGNC:26404 | Ensembl Gene: ENSG00000152620 | OMIM ID: 615787 |
| Drug and gene relationship at DGIdb | |||
Expression of NADK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NADK2 | 133686 | 228594_at | 0.1559 | 0.8103 | |
| GSE26886 | NADK2 | 133686 | 228594_at | 0.7834 | 0.0088 | |
| GSE45670 | NADK2 | 133686 | 228594_at | -0.1344 | 0.6202 | |
| GSE53622 | NADK2 | 133686 | 88720 | 0.1456 | 0.1495 | |
| GSE53624 | NADK2 | 133686 | 88720 | 0.1971 | 0.0054 | |
| GSE63941 | NADK2 | 133686 | 226946_at | 1.0571 | 0.0126 | |
| GSE77861 | NADK2 | 133686 | 228594_at | 0.0180 | 0.9512 | |
| SRP007169 | NADK2 | 133686 | RNAseq | 0.4672 | 0.3088 | |
| SRP008496 | NADK2 | 133686 | RNAseq | 0.4661 | 0.1560 | |
| SRP064894 | NADK2 | 133686 | RNAseq | 0.1053 | 0.5333 | |
| SRP133303 | NADK2 | 133686 | RNAseq | 0.2638 | 0.2421 | |
| SRP159526 | NADK2 | 133686 | RNAseq | 0.4806 | 0.0720 | |
| SRP193095 | NADK2 | 133686 | RNAseq | -0.1305 | 0.2863 | |
| SRP219564 | NADK2 | 133686 | RNAseq | 0.0989 | 0.8047 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NADK2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NADK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NADK2 | 133686 | 10 | 0 | 20 | |
| GSE20123 | NADK2 | 133686 | 10 | 0 | 20 | |
| GSE43470 | NADK2 | 133686 | 17 | 0 | 26 | |
| GSE46452 | NADK2 | 133686 | 5 | 22 | 32 | |
| GSE47630 | NADK2 | 133686 | 6 | 12 | 22 | |
| GSE54993 | NADK2 | 133686 | 5 | 4 | 61 | |
| GSE54994 | NADK2 | 133686 | 26 | 2 | 25 | |
| GSE60625 | NADK2 | 133686 | 0 | 0 | 11 | |
| GSE74703 | NADK2 | 133686 | 13 | 0 | 23 | |
| GSE74704 | NADK2 | 133686 | 9 | 0 | 11 | |
| TCGA | NADK2 | 133686 | 52 | 6 | 38 |
Total number of gains: 153; Total number of losses: 46; Total Number of normals: 289.
Somatic mutations of NADK2:
Generating mutation plots.
Highly correlated genes for NADK2:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NADK2 | RPL22 | 0.688527 | 3 | 0 | 3 |
| NADK2 | GATC | 0.668048 | 4 | 0 | 4 |
| NADK2 | TAF4 | 0.663478 | 3 | 0 | 3 |
| NADK2 | IFT74 | 0.653742 | 3 | 0 | 3 |
| NADK2 | SKP2 | 0.645642 | 4 | 0 | 3 |
| NADK2 | EXOSC10 | 0.643319 | 3 | 0 | 3 |
| NADK2 | CMTR1 | 0.63141 | 3 | 0 | 3 |
| NADK2 | RPS21 | 0.622735 | 3 | 0 | 3 |
| NADK2 | MTHFD2L | 0.609963 | 3 | 0 | 3 |
| NADK2 | HNRNPD | 0.605691 | 3 | 0 | 3 |
| NADK2 | C1orf174 | 0.601746 | 4 | 0 | 3 |
| NADK2 | ARL6IP1 | 0.594302 | 3 | 0 | 3 |
| NADK2 | NUCKS1 | 0.586587 | 3 | 0 | 3 |
| NADK2 | REPS2 | 0.586303 | 4 | 0 | 3 |
| NADK2 | GOLPH3 | 0.584256 | 4 | 0 | 3 |
| NADK2 | TDRKH | 0.578357 | 3 | 0 | 3 |
| NADK2 | TSPAN13 | 0.570235 | 3 | 0 | 3 |
| NADK2 | PAIP1 | 0.564159 | 5 | 0 | 3 |
| NADK2 | FZD3 | 0.561233 | 4 | 0 | 3 |
| NADK2 | ALMS1 | 0.560216 | 4 | 0 | 3 |
For details and further investigation, click here
