| Full name: TNFAIP3 interacting protein 3 | Alias Symbol: LIND|FLJ21162|ABIN-3 | ||
| Type: protein-coding gene | Cytoband: 4q27 | ||
| Entrez ID: 79931 | HGNC ID: HGNC:19315 | Ensembl Gene: ENSG00000050730 | OMIM ID: 608019 |
| Drug and gene relationship at DGIdb | |||
Expression of TNIP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNIP3 | 79931 | 220655_at | 1.3567 | 0.1323 | |
| GSE20347 | TNIP3 | 79931 | 220655_at | 0.2670 | 0.0125 | |
| GSE23400 | TNIP3 | 79931 | 220655_at | 0.1196 | 0.0006 | |
| GSE26886 | TNIP3 | 79931 | 220655_at | -0.0885 | 0.7900 | |
| GSE29001 | TNIP3 | 79931 | 220655_at | 0.4079 | 0.0932 | |
| GSE38129 | TNIP3 | 79931 | 220655_at | 0.3578 | 0.0031 | |
| GSE45670 | TNIP3 | 79931 | 220655_at | 0.7804 | 0.0319 | |
| GSE53622 | TNIP3 | 79931 | 69023 | 0.8784 | 0.0000 | |
| GSE53624 | TNIP3 | 79931 | 69023 | 1.3510 | 0.0000 | |
| GSE63941 | TNIP3 | 79931 | 220655_at | -0.0674 | 0.7893 | |
| GSE77861 | TNIP3 | 79931 | 220655_at | 0.3214 | 0.3433 | |
| GSE97050 | TNIP3 | 79931 | A_23_P386478 | 0.6621 | 0.1816 | |
| SRP133303 | TNIP3 | 79931 | RNAseq | 1.0121 | 0.0004 | |
| SRP159526 | TNIP3 | 79931 | RNAseq | 1.7667 | 0.0324 | |
| SRP193095 | TNIP3 | 79931 | RNAseq | 1.8134 | 0.0000 | |
| SRP219564 | TNIP3 | 79931 | RNAseq | 1.3612 | 0.0202 | |
| TCGA | TNIP3 | 79931 | RNAseq | 2.2546 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by TNIP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNIP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNIP3 | 79931 | 0 | 13 | 17 | |
| GSE20123 | TNIP3 | 79931 | 0 | 13 | 17 | |
| GSE43470 | TNIP3 | 79931 | 0 | 13 | 30 | |
| GSE46452 | TNIP3 | 79931 | 1 | 36 | 22 | |
| GSE47630 | TNIP3 | 79931 | 0 | 22 | 18 | |
| GSE54993 | TNIP3 | 79931 | 9 | 0 | 61 | |
| GSE54994 | TNIP3 | 79931 | 1 | 10 | 42 | |
| GSE60625 | TNIP3 | 79931 | 0 | 1 | 10 | |
| GSE74703 | TNIP3 | 79931 | 0 | 11 | 25 | |
| GSE74704 | TNIP3 | 79931 | 0 | 7 | 13 | |
| TCGA | TNIP3 | 79931 | 8 | 34 | 54 |
Total number of gains: 19; Total number of losses: 160; Total Number of normals: 309.
Somatic mutations of TNIP3:
Generating mutation plots.
Highly correlated genes for TNIP3:
Showing top 20/449 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNIP3 | NCEH1 | 0.704542 | 3 | 0 | 3 |
| TNIP3 | LPAR3 | 0.687161 | 3 | 0 | 3 |
| TNIP3 | RNASEH1 | 0.684329 | 3 | 0 | 3 |
| TNIP3 | SLC36A1 | 0.679721 | 4 | 0 | 3 |
| TNIP3 | SEC61G | 0.665285 | 3 | 0 | 3 |
| TNIP3 | RNF149 | 0.659169 | 3 | 0 | 3 |
| TNIP3 | ARL13B | 0.65331 | 3 | 0 | 3 |
| TNIP3 | FASTKD3 | 0.645266 | 4 | 0 | 3 |
| TNIP3 | UBE2E3 | 0.64494 | 4 | 0 | 3 |
| TNIP3 | CHST1 | 0.643676 | 5 | 0 | 3 |
| TNIP3 | NFKB2 | 0.640985 | 4 | 0 | 3 |
| TNIP3 | SHCBP1 | 0.640596 | 6 | 0 | 4 |
| TNIP3 | ZMYM1 | 0.63631 | 4 | 0 | 3 |
| TNIP3 | DHRS13 | 0.635818 | 3 | 0 | 3 |
| TNIP3 | C12orf60 | 0.635196 | 3 | 0 | 3 |
| TNIP3 | PNO1 | 0.634952 | 4 | 0 | 3 |
| TNIP3 | OSBPL3 | 0.632653 | 4 | 0 | 3 |
| TNIP3 | ZNF622 | 0.632201 | 4 | 0 | 3 |
| TNIP3 | CEP19 | 0.632089 | 4 | 0 | 3 |
| TNIP3 | C12orf75 | 0.630225 | 5 | 0 | 4 |
For details and further investigation, click here
