| Full name: neuroepithelial cell transforming 1 | Alias Symbol: ARHGEF8|NET1A | ||
| Type: protein-coding gene | Cytoband: 10p15.1 | ||
| Entrez ID: 10276 | HGNC ID: HGNC:14592 | Ensembl Gene: ENSG00000173848 | OMIM ID: 606450 |
| Drug and gene relationship at DGIdb | |||
Expression of NET1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NET1 | 10276 | 201830_s_at | -0.8316 | 0.2089 | |
| GSE20347 | NET1 | 10276 | 201829_at | -0.0966 | 0.6683 | |
| GSE23400 | NET1 | 10276 | 201830_s_at | -0.0547 | 0.6451 | |
| GSE26886 | NET1 | 10276 | 201829_at | -0.6729 | 0.0187 | |
| GSE29001 | NET1 | 10276 | 201829_at | -0.2381 | 0.3127 | |
| GSE38129 | NET1 | 10276 | 201829_at | -0.0197 | 0.9187 | |
| GSE45670 | NET1 | 10276 | 201829_at | -0.0078 | 0.9761 | |
| GSE53622 | NET1 | 10276 | 111062 | -0.3064 | 0.0005 | |
| GSE53624 | NET1 | 10276 | 7794 | -0.5125 | 0.0000 | |
| GSE63941 | NET1 | 10276 | 201830_s_at | 2.6967 | 0.0001 | |
| GSE77861 | NET1 | 10276 | 201830_s_at | 0.0245 | 0.9394 | |
| GSE97050 | NET1 | 10276 | A_23_P83931 | -0.5776 | 0.1703 | |
| SRP007169 | NET1 | 10276 | RNAseq | -0.0048 | 0.9883 | |
| SRP008496 | NET1 | 10276 | RNAseq | 0.3122 | 0.2213 | |
| SRP064894 | NET1 | 10276 | RNAseq | -0.6852 | 0.0022 | |
| SRP133303 | NET1 | 10276 | RNAseq | -0.2300 | 0.2214 | |
| SRP159526 | NET1 | 10276 | RNAseq | -0.6117 | 0.0237 | |
| SRP193095 | NET1 | 10276 | RNAseq | -0.3053 | 0.0236 | |
| SRP219564 | NET1 | 10276 | RNAseq | -0.8485 | 0.1097 | |
| TCGA | NET1 | 10276 | RNAseq | -0.0064 | 0.9085 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NET1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NET1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NET1 | 10276 | 6 | 7 | 17 | |
| GSE20123 | NET1 | 10276 | 6 | 6 | 18 | |
| GSE43470 | NET1 | 10276 | 4 | 6 | 33 | |
| GSE46452 | NET1 | 10276 | 2 | 14 | 43 | |
| GSE47630 | NET1 | 10276 | 6 | 14 | 20 | |
| GSE54993 | NET1 | 10276 | 11 | 0 | 59 | |
| GSE54994 | NET1 | 10276 | 5 | 10 | 38 | |
| GSE60625 | NET1 | 10276 | 0 | 0 | 11 | |
| GSE74703 | NET1 | 10276 | 3 | 4 | 29 | |
| GSE74704 | NET1 | 10276 | 1 | 5 | 14 | |
| TCGA | NET1 | 10276 | 21 | 24 | 51 |
Total number of gains: 65; Total number of losses: 90; Total Number of normals: 333.
Somatic mutations of NET1:
Generating mutation plots.
Highly correlated genes for NET1:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NET1 | C2orf73 | 0.674298 | 3 | 0 | 3 |
| NET1 | FZD5 | 0.651629 | 4 | 0 | 4 |
| NET1 | AHNAK | 0.648875 | 4 | 0 | 3 |
| NET1 | EPHX2 | 0.643627 | 4 | 0 | 3 |
| NET1 | NCALD | 0.641953 | 3 | 0 | 3 |
| NET1 | OR12D2 | 0.633977 | 3 | 0 | 3 |
| NET1 | STH | 0.630602 | 3 | 0 | 3 |
| NET1 | UBE2D2 | 0.615707 | 4 | 0 | 3 |
| NET1 | OCLN | 0.611814 | 3 | 0 | 3 |
| NET1 | HCAR3 | 0.599619 | 4 | 0 | 3 |
| NET1 | STAB2 | 0.591298 | 4 | 0 | 3 |
| NET1 | TRIP10 | 0.578546 | 4 | 0 | 3 |
| NET1 | FBXW11 | 0.57622 | 4 | 0 | 3 |
| NET1 | FBXO38 | 0.575984 | 3 | 0 | 3 |
| NET1 | ANK3 | 0.575442 | 7 | 0 | 4 |
| NET1 | NDRG2 | 0.56855 | 5 | 0 | 4 |
| NET1 | PAX9 | 0.565351 | 4 | 0 | 4 |
| NET1 | ABLIM1 | 0.555371 | 4 | 0 | 3 |
| NET1 | IK | 0.555317 | 4 | 0 | 3 |
| NET1 | MPP7 | 0.553236 | 5 | 0 | 3 |
For details and further investigation, click here
