| Full name: reticulocalbin 3 | Alias Symbol: RLP49 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 57333 | HGNC ID: HGNC:21145 | Ensembl Gene: ENSG00000142552 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RCN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCN3 | 57333 | 61734_at | 0.5067 | 0.3377 | |
| GSE20347 | RCN3 | 57333 | 219102_at | 0.0989 | 0.2380 | |
| GSE23400 | RCN3 | 57333 | 61734_at | 0.4132 | 0.0000 | |
| GSE26886 | RCN3 | 57333 | 219102_at | 0.0306 | 0.8903 | |
| GSE29001 | RCN3 | 57333 | 61734_at | 0.4552 | 0.1175 | |
| GSE38129 | RCN3 | 57333 | 61734_at | 0.4493 | 0.0488 | |
| GSE45670 | RCN3 | 57333 | 219102_at | -0.1521 | 0.1145 | |
| GSE53622 | RCN3 | 57333 | 100137 | 1.4814 | 0.0000 | |
| GSE53624 | RCN3 | 57333 | 100137 | 1.6414 | 0.0000 | |
| GSE63941 | RCN3 | 57333 | 219102_at | -1.1350 | 0.0071 | |
| GSE77861 | RCN3 | 57333 | 219102_at | -0.1848 | 0.2768 | |
| GSE97050 | RCN3 | 57333 | A_23_P67339 | 0.7147 | 0.1126 | |
| SRP007169 | RCN3 | 57333 | RNAseq | 4.0784 | 0.0000 | |
| SRP008496 | RCN3 | 57333 | RNAseq | 3.4933 | 0.0000 | |
| SRP064894 | RCN3 | 57333 | RNAseq | 2.4084 | 0.0000 | |
| SRP133303 | RCN3 | 57333 | RNAseq | 2.1138 | 0.0000 | |
| SRP159526 | RCN3 | 57333 | RNAseq | 1.3363 | 0.0002 | |
| SRP193095 | RCN3 | 57333 | RNAseq | 3.0407 | 0.0000 | |
| SRP219564 | RCN3 | 57333 | RNAseq | 2.0638 | 0.0002 | |
| TCGA | RCN3 | 57333 | RNAseq | 0.5606 | 0.0001 |
Upregulated datasets: 9; Downregulated datasets: 1.
Survival by RCN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RCN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCN3 | 57333 | 4 | 4 | 22 | |
| GSE20123 | RCN3 | 57333 | 4 | 3 | 23 | |
| GSE43470 | RCN3 | 57333 | 4 | 11 | 28 | |
| GSE46452 | RCN3 | 57333 | 45 | 1 | 13 | |
| GSE47630 | RCN3 | 57333 | 10 | 6 | 24 | |
| GSE54993 | RCN3 | 57333 | 17 | 4 | 49 | |
| GSE54994 | RCN3 | 57333 | 4 | 14 | 35 | |
| GSE60625 | RCN3 | 57333 | 9 | 0 | 2 | |
| GSE74703 | RCN3 | 57333 | 4 | 7 | 25 | |
| GSE74704 | RCN3 | 57333 | 4 | 1 | 15 | |
| TCGA | RCN3 | 57333 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of RCN3:
Generating mutation plots.
Highly correlated genes for RCN3:
Showing top 20/583 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCN3 | WDR54 | 0.774587 | 3 | 0 | 3 |
| RCN3 | ADAM12 | 0.756683 | 6 | 0 | 6 |
| RCN3 | P4HA2 | 0.751293 | 3 | 0 | 3 |
| RCN3 | INHBA | 0.750178 | 8 | 0 | 8 |
| RCN3 | OLFML2B | 0.740395 | 10 | 0 | 8 |
| RCN3 | PLXNC1 | 0.739834 | 6 | 0 | 6 |
| RCN3 | THY1 | 0.721619 | 11 | 0 | 10 |
| RCN3 | CALU | 0.721377 | 8 | 0 | 7 |
| RCN3 | VCAN | 0.720982 | 9 | 0 | 8 |
| RCN3 | GALNT10 | 0.719373 | 7 | 0 | 6 |
| RCN3 | COL5A1 | 0.708416 | 11 | 0 | 9 |
| RCN3 | ADAMTS12 | 0.703875 | 7 | 0 | 5 |
| RCN3 | CTHRC1 | 0.702812 | 6 | 0 | 5 |
| RCN3 | COL24A1 | 0.702377 | 3 | 0 | 3 |
| RCN3 | POSTN | 0.701243 | 10 | 0 | 8 |
| RCN3 | PCOLCE | 0.700501 | 12 | 0 | 9 |
| RCN3 | CHN1 | 0.696314 | 9 | 0 | 7 |
| RCN3 | CDH11 | 0.696038 | 9 | 0 | 8 |
| RCN3 | C4orf48 | 0.695906 | 4 | 0 | 3 |
| RCN3 | PLBD2 | 0.694072 | 5 | 0 | 5 |
For details and further investigation, click here
