| Full name: NME/NM23 nucleoside diphosphate kinase 1 | Alias Symbol: NM23|NM23-H1|NDPKA | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 4830 | HGNC ID: HGNC:7849 | Ensembl Gene: ENSG00000239672 | OMIM ID: 156490 |
| Drug and gene relationship at DGIdb | |||
Expression of NME1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NME1 | 4830 | 201577_at | 0.6781 | 0.0653 | |
| GSE20347 | NME1 | 4830 | 201577_at | 0.5925 | 0.0036 | |
| GSE23400 | NME1 | 4830 | 201577_at | 0.9801 | 0.0000 | |
| GSE26886 | NME1 | 4830 | 201577_at | 0.2884 | 0.2335 | |
| GSE29001 | NME1 | 4830 | 201577_at | 0.6843 | 0.0938 | |
| GSE38129 | NME1 | 4830 | 201577_at | 1.0793 | 0.0000 | |
| GSE45670 | NME1 | 4830 | 201577_at | 0.7414 | 0.0003 | |
| GSE53622 | NME1 | 4830 | 24689 | 0.6844 | 0.0000 | |
| GSE53624 | NME1 | 4830 | 24689 | 0.8343 | 0.0000 | |
| GSE63941 | NME1 | 4830 | 201577_at | 0.5488 | 0.1650 | |
| GSE77861 | NME1 | 4830 | 201577_at | 0.6886 | 0.0089 | |
| GSE97050 | NME1 | 4830 | A_23_P152804 | 0.9354 | 0.1387 | |
| SRP007169 | NME1 | 4830 | RNAseq | 0.6351 | 0.1443 | |
| SRP008496 | NME1 | 4830 | RNAseq | 0.4745 | 0.1042 | |
| SRP064894 | NME1 | 4830 | RNAseq | 1.0583 | 0.0006 | |
| SRP133303 | NME1 | 4830 | RNAseq | 0.8395 | 0.0000 | |
| SRP159526 | NME1 | 4830 | RNAseq | 0.7921 | 0.0080 | |
| SRP193095 | NME1 | 4830 | RNAseq | 0.0726 | 0.6780 | |
| SRP219564 | NME1 | 4830 | RNAseq | 0.9206 | 0.0612 | |
| TCGA | NME1 | 4830 | RNAseq | 0.5205 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NME1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NME1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NME1 | 4830 | 5 | 2 | 23 | |
| GSE20123 | NME1 | 4830 | 5 | 2 | 23 | |
| GSE43470 | NME1 | 4830 | 3 | 2 | 38 | |
| GSE46452 | NME1 | 4830 | 32 | 0 | 27 | |
| GSE47630 | NME1 | 4830 | 9 | 0 | 31 | |
| GSE54993 | NME1 | 4830 | 2 | 4 | 64 | |
| GSE54994 | NME1 | 4830 | 8 | 6 | 39 | |
| GSE60625 | NME1 | 4830 | 4 | 0 | 7 | |
| GSE74703 | NME1 | 4830 | 3 | 2 | 31 | |
| GSE74704 | NME1 | 4830 | 4 | 1 | 15 | |
| TCGA | NME1 | 4830 | 26 | 8 | 62 |
Total number of gains: 101; Total number of losses: 27; Total Number of normals: 360.
Somatic mutations of NME1:
Generating mutation plots.
Highly correlated genes for NME1:
Showing top 20/1885 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NME1 | SLC30A7 | 0.7959 | 3 | 0 | 3 |
| NME1 | RAN | 0.75769 | 12 | 0 | 11 |
| NME1 | PSMA7 | 0.75536 | 9 | 0 | 9 |
| NME1 | SPRED1 | 0.749614 | 3 | 0 | 3 |
| NME1 | BUB1 | 0.745109 | 9 | 0 | 9 |
| NME1 | BIRC5 | 0.741778 | 11 | 0 | 11 |
| NME1 | CCT5 | 0.740922 | 9 | 0 | 8 |
| NME1 | PDIA6 | 0.736125 | 10 | 0 | 9 |
| NME1 | LRRC59 | 0.733486 | 10 | 0 | 9 |
| NME1 | CENPW | 0.732366 | 6 | 0 | 6 |
| NME1 | PSMG3 | 0.731796 | 6 | 0 | 6 |
| NME1 | CLSPN | 0.729242 | 6 | 0 | 6 |
| NME1 | DCAF13 | 0.726174 | 7 | 0 | 7 |
| NME1 | CKS1B | 0.725911 | 12 | 0 | 11 |
| NME1 | KPNA2 | 0.72513 | 8 | 0 | 7 |
| NME1 | UBE2C | 0.72394 | 12 | 0 | 11 |
| NME1 | FAM89A | 0.723762 | 3 | 0 | 3 |
| NME1 | CCNB1 | 0.722233 | 10 | 0 | 9 |
| NME1 | DCBLD1 | 0.721973 | 6 | 0 | 5 |
| NME1 | SLC26A6 | 0.720721 | 3 | 0 | 3 |
For details and further investigation, click here
