| Full name: nicotinamide riboside kinase 2 | Alias Symbol: MIBP|NRK2 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 27231 | HGNC ID: HGNC:17871 | Ensembl Gene: ENSG00000077009 | OMIM ID: 608705 |
| Drug and gene relationship at DGIdb | |||
Expression of NMRK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NMRK2 | 27231 | 221051_s_at | -0.0679 | 0.8447 | |
| GSE20347 | NMRK2 | 27231 | 221051_s_at | -0.1730 | 0.0055 | |
| GSE23400 | NMRK2 | 27231 | 221051_s_at | -0.1348 | 0.0001 | |
| GSE26886 | NMRK2 | 27231 | 221051_s_at | 0.2241 | 0.0120 | |
| GSE29001 | NMRK2 | 27231 | 221051_s_at | -0.0489 | 0.7413 | |
| GSE38129 | NMRK2 | 27231 | 221051_s_at | -0.3149 | 0.0002 | |
| GSE45670 | NMRK2 | 27231 | 221051_s_at | -0.0430 | 0.6880 | |
| GSE53622 | NMRK2 | 27231 | 102808 | -0.5661 | 0.0127 | |
| GSE53624 | NMRK2 | 27231 | 102808 | -0.9626 | 0.0000 | |
| GSE63941 | NMRK2 | 27231 | 221051_s_at | 0.1743 | 0.2825 | |
| GSE77861 | NMRK2 | 27231 | 221051_s_at | -0.1002 | 0.4208 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NMRK2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NMRK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NMRK2 | 27231 | 5 | 3 | 22 | |
| GSE20123 | NMRK2 | 27231 | 4 | 2 | 24 | |
| GSE43470 | NMRK2 | 27231 | 1 | 9 | 33 | |
| GSE46452 | NMRK2 | 27231 | 47 | 1 | 11 | |
| GSE47630 | NMRK2 | 27231 | 5 | 7 | 28 | |
| GSE54993 | NMRK2 | 27231 | 16 | 3 | 51 | |
| GSE54994 | NMRK2 | 27231 | 8 | 16 | 29 | |
| GSE60625 | NMRK2 | 27231 | 9 | 0 | 2 | |
| GSE74703 | NMRK2 | 27231 | 1 | 6 | 29 | |
| GSE74704 | NMRK2 | 27231 | 1 | 2 | 17 | |
| TCGA | NMRK2 | 27231 | 11 | 18 | 67 |
Total number of gains: 108; Total number of losses: 67; Total Number of normals: 313.
Somatic mutations of NMRK2:
Generating mutation plots.
Highly correlated genes for NMRK2:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NMRK2 | UNC5A | 0.780299 | 3 | 0 | 3 |
| NMRK2 | HMCN2 | 0.753943 | 4 | 0 | 4 |
| NMRK2 | ATP6V1B1 | 0.662762 | 3 | 0 | 3 |
| NMRK2 | MAG | 0.646416 | 4 | 0 | 3 |
| NMRK2 | PKLR | 0.633812 | 3 | 0 | 3 |
| NMRK2 | SSC5D | 0.630704 | 3 | 0 | 3 |
| NMRK2 | ZDHHC1 | 0.617399 | 3 | 0 | 3 |
| NMRK2 | MATN4 | 0.615196 | 5 | 0 | 3 |
| NMRK2 | MYH7B | 0.612845 | 4 | 0 | 3 |
| NMRK2 | LCN1 | 0.609986 | 3 | 0 | 3 |
| NMRK2 | ACHE | 0.606504 | 4 | 0 | 3 |
| NMRK2 | EVX1 | 0.60508 | 4 | 0 | 3 |
| NMRK2 | NOXO1 | 0.604435 | 3 | 0 | 3 |
| NMRK2 | DMTN | 0.603112 | 4 | 0 | 3 |
| NMRK2 | CHD5 | 0.600467 | 6 | 0 | 4 |
| NMRK2 | ELANE | 0.600055 | 5 | 0 | 5 |
| NMRK2 | PPP1R32 | 0.598034 | 4 | 0 | 3 |
| NMRK2 | NKAIN4 | 0.597387 | 3 | 0 | 3 |
| NMRK2 | FIBCD1 | 0.596924 | 3 | 0 | 3 |
| NMRK2 | DMRTA1 | 0.595226 | 4 | 0 | 3 |
For details and further investigation, click here
