| Full name: ATPase H+ transporting V1 subunit B1 | Alias Symbol: VATB|RTA1B|Vma2 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 525 | HGNC ID: HGNC:853 | Ensembl Gene: ENSG00000116039 | OMIM ID: 192132 |
| Drug and gene relationship at DGIdb | |||
ATP6V1B1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04150 | mTOR signaling pathway | |
| hsa05110 | Vibrio cholerae infection | |
| hsa05120 | Epithelial cell signaling in Helicobacter pylori infection |
Expression of ATP6V1B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP6V1B1 | 525 | 205473_at | 0.3121 | 0.3325 | |
| GSE20347 | ATP6V1B1 | 525 | 205473_at | -0.0027 | 0.9856 | |
| GSE23400 | ATP6V1B1 | 525 | 205473_at | -0.0135 | 0.6810 | |
| GSE26886 | ATP6V1B1 | 525 | 1554847_at | 0.1808 | 0.1721 | |
| GSE29001 | ATP6V1B1 | 525 | 205473_at | -0.1362 | 0.2067 | |
| GSE38129 | ATP6V1B1 | 525 | 205473_at | 0.0897 | 0.2906 | |
| GSE45670 | ATP6V1B1 | 525 | 1554847_at | 0.0795 | 0.4167 | |
| GSE53622 | ATP6V1B1 | 525 | 63085 | 0.4147 | 0.0261 | |
| GSE53624 | ATP6V1B1 | 525 | 63085 | 0.1475 | 0.2634 | |
| GSE63941 | ATP6V1B1 | 525 | 205473_at | 0.5366 | 0.2042 | |
| GSE77861 | ATP6V1B1 | 525 | 1554847_at | -0.0025 | 0.9908 | |
| SRP133303 | ATP6V1B1 | 525 | RNAseq | 0.1613 | 0.7324 | |
| SRP159526 | ATP6V1B1 | 525 | RNAseq | 2.9273 | 0.0008 | |
| SRP219564 | ATP6V1B1 | 525 | RNAseq | 1.8074 | 0.0082 | |
| TCGA | ATP6V1B1 | 525 | RNAseq | 1.7123 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ATP6V1B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP6V1B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP6V1B1 | 525 | 11 | 1 | 18 | |
| GSE20123 | ATP6V1B1 | 525 | 11 | 1 | 18 | |
| GSE43470 | ATP6V1B1 | 525 | 3 | 0 | 40 | |
| GSE46452 | ATP6V1B1 | 525 | 2 | 3 | 54 | |
| GSE47630 | ATP6V1B1 | 525 | 7 | 0 | 33 | |
| GSE54993 | ATP6V1B1 | 525 | 0 | 6 | 64 | |
| GSE54994 | ATP6V1B1 | 525 | 11 | 0 | 42 | |
| GSE60625 | ATP6V1B1 | 525 | 0 | 3 | 8 | |
| GSE74703 | ATP6V1B1 | 525 | 3 | 0 | 33 | |
| GSE74704 | ATP6V1B1 | 525 | 9 | 0 | 11 | |
| TCGA | ATP6V1B1 | 525 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of ATP6V1B1:
Generating mutation plots.
Highly correlated genes for ATP6V1B1:
Showing top 20/80 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP6V1B1 | AGER | 0.685823 | 3 | 0 | 3 |
| ATP6V1B1 | MPL | 0.669738 | 3 | 0 | 3 |
| ATP6V1B1 | TCAP | 0.665235 | 3 | 0 | 3 |
| ATP6V1B1 | NMRK2 | 0.662762 | 3 | 0 | 3 |
| ATP6V1B1 | IGH | 0.660514 | 3 | 0 | 3 |
| ATP6V1B1 | IL18BP | 0.645302 | 3 | 0 | 3 |
| ATP6V1B1 | CASR | 0.637606 | 3 | 0 | 3 |
| ATP6V1B1 | TP53TG5 | 0.626963 | 3 | 0 | 3 |
| ATP6V1B1 | PKLR | 0.626654 | 4 | 0 | 3 |
| ATP6V1B1 | CPLX2 | 0.625877 | 3 | 0 | 3 |
| ATP6V1B1 | HTR7 | 0.617903 | 3 | 0 | 3 |
| ATP6V1B1 | LCN1 | 0.610633 | 3 | 0 | 3 |
| ATP6V1B1 | KCNQ4 | 0.610629 | 3 | 0 | 3 |
| ATP6V1B1 | PNMT | 0.606707 | 4 | 0 | 3 |
| ATP6V1B1 | CCL27 | 0.604648 | 3 | 0 | 3 |
| ATP6V1B1 | ADAMTS7 | 0.599267 | 4 | 0 | 3 |
| ATP6V1B1 | BIRC7 | 0.599263 | 3 | 0 | 3 |
| ATP6V1B1 | CACNA1H | 0.59385 | 4 | 0 | 3 |
| ATP6V1B1 | NTN3 | 0.591952 | 4 | 0 | 3 |
| ATP6V1B1 | GRAP | 0.588893 | 3 | 0 | 3 |
For details and further investigation, click here
