| Full name: neuritin 1 | Alias Symbol: NRN | ||
| Type: protein-coding gene | Cytoband: 6p25.1 | ||
| Entrez ID: 51299 | HGNC ID: HGNC:17972 | Ensembl Gene: ENSG00000124785 | OMIM ID: 607409 |
| Drug and gene relationship at DGIdb | |||
Expression of NRN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRN1 | 51299 | 218625_at | -0.1944 | 0.9477 | |
| GSE20347 | NRN1 | 51299 | 218625_at | 1.0624 | 0.0055 | |
| GSE23400 | NRN1 | 51299 | 218625_at | 0.3304 | 0.0836 | |
| GSE26886 | NRN1 | 51299 | 218625_at | 1.1861 | 0.0526 | |
| GSE29001 | NRN1 | 51299 | 218625_at | 0.7692 | 0.0770 | |
| GSE38129 | NRN1 | 51299 | 218625_at | 0.5041 | 0.2544 | |
| GSE45670 | NRN1 | 51299 | 218625_at | -1.0285 | 0.1017 | |
| GSE53622 | NRN1 | 51299 | 53084 | -0.6294 | 0.0026 | |
| GSE53624 | NRN1 | 51299 | 53084 | 0.0087 | 0.9649 | |
| GSE63941 | NRN1 | 51299 | 218625_at | 1.3098 | 0.4290 | |
| GSE77861 | NRN1 | 51299 | 218625_at | 1.2281 | 0.0888 | |
| GSE97050 | NRN1 | 51299 | A_23_P414519 | -0.4665 | 0.3073 | |
| SRP007169 | NRN1 | 51299 | RNAseq | 4.1409 | 0.0001 | |
| SRP064894 | NRN1 | 51299 | RNAseq | 0.1066 | 0.7584 | |
| SRP133303 | NRN1 | 51299 | RNAseq | 0.3325 | 0.5975 | |
| SRP159526 | NRN1 | 51299 | RNAseq | 0.4156 | 0.4368 | |
| SRP219564 | NRN1 | 51299 | RNAseq | -0.1431 | 0.8459 | |
| TCGA | NRN1 | 51299 | RNAseq | -0.1673 | 0.5109 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NRN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRN1 | 51299 | 3 | 6 | 21 | |
| GSE20123 | NRN1 | 51299 | 3 | 6 | 21 | |
| GSE43470 | NRN1 | 51299 | 8 | 2 | 33 | |
| GSE46452 | NRN1 | 51299 | 1 | 10 | 48 | |
| GSE47630 | NRN1 | 51299 | 7 | 8 | 25 | |
| GSE54993 | NRN1 | 51299 | 1 | 1 | 68 | |
| GSE54994 | NRN1 | 51299 | 10 | 3 | 40 | |
| GSE60625 | NRN1 | 51299 | 0 | 1 | 10 | |
| GSE74703 | NRN1 | 51299 | 7 | 2 | 27 | |
| GSE74704 | NRN1 | 51299 | 2 | 2 | 16 | |
| TCGA | NRN1 | 51299 | 15 | 28 | 53 |
Total number of gains: 57; Total number of losses: 69; Total Number of normals: 362.
Somatic mutations of NRN1:
Generating mutation plots.
Highly correlated genes for NRN1:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRN1 | ASB2 | 0.66994 | 3 | 0 | 3 |
| NRN1 | ARHGEF40 | 0.637036 | 4 | 0 | 4 |
| NRN1 | GABRR1 | 0.621477 | 4 | 0 | 3 |
| NRN1 | MCF2L-AS1 | 0.61925 | 4 | 0 | 3 |
| NRN1 | COPZ2 | 0.615464 | 3 | 0 | 3 |
| NRN1 | MFAP5 | 0.612819 | 5 | 0 | 4 |
| NRN1 | SLC12A7 | 0.612326 | 4 | 0 | 3 |
| NRN1 | CCDC102B | 0.597663 | 4 | 0 | 4 |
| NRN1 | LINC-PINT | 0.594616 | 3 | 0 | 3 |
| NRN1 | BEX2 | 0.594244 | 4 | 0 | 3 |
| NRN1 | MN1 | 0.591842 | 5 | 0 | 3 |
| NRN1 | SIRT5 | 0.59067 | 3 | 0 | 3 |
| NRN1 | NR1H3 | 0.58327 | 4 | 0 | 3 |
| NRN1 | GGT7 | 0.582051 | 3 | 0 | 3 |
| NRN1 | LRIG1 | 0.581046 | 6 | 0 | 4 |
| NRN1 | DUSP2 | 0.580926 | 3 | 0 | 3 |
| NRN1 | CD81 | 0.57774 | 6 | 0 | 3 |
| NRN1 | DCLK1 | 0.570662 | 7 | 0 | 5 |
| NRN1 | ATAD5 | 0.570662 | 3 | 0 | 3 |
| NRN1 | HTR2C | 0.568796 | 4 | 0 | 4 |
For details and further investigation, click here
