| Full name: 2-oxoglutarate and iron dependent oxygenase domain containing 3 | Alias Symbol: FLJ22222 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 79701 | HGNC ID: HGNC:26174 | Ensembl Gene: ENSG00000181396 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of OGFOD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OGFOD3 | 79701 | 53071_s_at | 0.0155 | 0.9779 | |
| GSE20347 | OGFOD3 | 79701 | 53071_s_at | -0.5469 | 0.0155 | |
| GSE23400 | OGFOD3 | 79701 | 53071_s_at | 0.0729 | 0.4524 | |
| GSE26886 | OGFOD3 | 79701 | 53071_s_at | 1.0409 | 0.0027 | |
| GSE29001 | OGFOD3 | 79701 | 53071_s_at | 0.1174 | 0.7375 | |
| GSE38129 | OGFOD3 | 79701 | 53071_s_at | -0.3054 | 0.0509 | |
| GSE45670 | OGFOD3 | 79701 | 53071_s_at | -0.1482 | 0.4622 | |
| GSE53622 | OGFOD3 | 79701 | 80600 | 0.1218 | 0.1228 | |
| GSE53624 | OGFOD3 | 79701 | 80600 | -0.0382 | 0.7414 | |
| GSE63941 | OGFOD3 | 79701 | 53071_s_at | -0.7830 | 0.3432 | |
| GSE77861 | OGFOD3 | 79701 | 53071_s_at | -0.6948 | 0.0470 | |
| SRP007169 | OGFOD3 | 79701 | RNAseq | 0.2797 | 0.5466 | |
| SRP008496 | OGFOD3 | 79701 | RNAseq | 0.5091 | 0.1691 | |
| SRP064894 | OGFOD3 | 79701 | RNAseq | 0.6042 | 0.0311 | |
| SRP133303 | OGFOD3 | 79701 | RNAseq | 0.1153 | 0.4206 | |
| SRP159526 | OGFOD3 | 79701 | RNAseq | 0.3013 | 0.1778 | |
| SRP193095 | OGFOD3 | 79701 | RNAseq | 0.1377 | 0.0611 | |
| SRP219564 | OGFOD3 | 79701 | RNAseq | 0.3916 | 0.2451 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by OGFOD3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of OGFOD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OGFOD3 | 79701 | 4 | 5 | 21 | |
| GSE20123 | OGFOD3 | 79701 | 4 | 5 | 21 | |
| GSE43470 | OGFOD3 | 79701 | 3 | 5 | 35 | |
| GSE46452 | OGFOD3 | 79701 | 34 | 0 | 25 | |
| GSE47630 | OGFOD3 | 79701 | 9 | 2 | 29 | |
| GSE54993 | OGFOD3 | 79701 | 2 | 5 | 63 | |
| GSE54994 | OGFOD3 | 79701 | 10 | 6 | 37 | |
| GSE60625 | OGFOD3 | 79701 | 6 | 0 | 5 | |
| GSE74703 | OGFOD3 | 79701 | 3 | 3 | 30 | |
| GSE74704 | OGFOD3 | 79701 | 4 | 4 | 12 | |
| TCGA | OGFOD3 | 79701 | 23 | 13 | 60 |
Total number of gains: 102; Total number of losses: 48; Total Number of normals: 338.
Somatic mutations of OGFOD3:
Generating mutation plots.
Highly correlated genes for OGFOD3:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OGFOD3 | SFXN3 | 0.656791 | 3 | 0 | 3 |
| OGFOD3 | GBP3 | 0.639781 | 3 | 0 | 3 |
| OGFOD3 | KCNAB2 | 0.621664 | 3 | 0 | 3 |
| OGFOD3 | VDR | 0.614977 | 4 | 0 | 4 |
| OGFOD3 | TCIRG1 | 0.606348 | 3 | 0 | 3 |
| OGFOD3 | SDHAF1 | 0.597684 | 4 | 0 | 4 |
| OGFOD3 | RHBDF2 | 0.597409 | 3 | 0 | 3 |
| OGFOD3 | RNF167 | 0.587689 | 3 | 0 | 3 |
| OGFOD3 | ASL | 0.586588 | 4 | 0 | 3 |
| OGFOD3 | PIGK | 0.58215 | 4 | 0 | 3 |
| OGFOD3 | ATOX1 | 0.573783 | 6 | 0 | 5 |
| OGFOD3 | CCNJL | 0.572143 | 3 | 0 | 3 |
| OGFOD3 | PEX14 | 0.569744 | 5 | 0 | 3 |
| OGFOD3 | CTNS | 0.568593 | 3 | 0 | 3 |
| OGFOD3 | MRPL43 | 0.56713 | 3 | 0 | 3 |
| OGFOD3 | GAK | 0.562897 | 3 | 0 | 3 |
| OGFOD3 | PGM1 | 0.559737 | 3 | 0 | 3 |
| OGFOD3 | UQCRQ | 0.558517 | 4 | 0 | 3 |
| OGFOD3 | TMA7 | 0.555558 | 4 | 0 | 3 |
| OGFOD3 | CANT1 | 0.553063 | 5 | 0 | 4 |
For details and further investigation, click here
