| Full name: antioxidant 1 copper chaperone | Alias Symbol: HAH1 | ||
| Type: protein-coding gene | Cytoband: 5q33.1 | ||
| Entrez ID: 475 | HGNC ID: HGNC:798 | Ensembl Gene: ENSG00000177556 | OMIM ID: 602270 |
| Drug and gene relationship at DGIdb | |||
Expression of ATOX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATOX1 | 475 | 203454_s_at | -0.0680 | 0.9177 | |
| GSE20347 | ATOX1 | 475 | 203454_s_at | -0.5284 | 0.0105 | |
| GSE23400 | ATOX1 | 475 | 203454_s_at | -0.0726 | 0.3588 | |
| GSE26886 | ATOX1 | 475 | 203454_s_at | -0.0956 | 0.6986 | |
| GSE29001 | ATOX1 | 475 | 203454_s_at | -0.3330 | 0.2399 | |
| GSE38129 | ATOX1 | 475 | 203454_s_at | -0.3128 | 0.0647 | |
| GSE45670 | ATOX1 | 475 | 203454_s_at | 0.0279 | 0.8881 | |
| GSE53622 | ATOX1 | 475 | 73807 | -0.2356 | 0.0063 | |
| GSE53624 | ATOX1 | 475 | 73807 | -0.1921 | 0.0032 | |
| GSE63941 | ATOX1 | 475 | 203454_s_at | -0.8445 | 0.1724 | |
| GSE77861 | ATOX1 | 475 | 203454_s_at | -0.3445 | 0.2003 | |
| GSE97050 | ATOX1 | 475 | A_23_P144877 | -0.0357 | 0.9314 | |
| SRP007169 | ATOX1 | 475 | RNAseq | -1.5088 | 0.0005 | |
| SRP008496 | ATOX1 | 475 | RNAseq | -1.4312 | 0.0000 | |
| SRP064894 | ATOX1 | 475 | RNAseq | 0.0614 | 0.8539 | |
| SRP133303 | ATOX1 | 475 | RNAseq | -0.0935 | 0.6331 | |
| SRP159526 | ATOX1 | 475 | RNAseq | -0.4182 | 0.1555 | |
| SRP193095 | ATOX1 | 475 | RNAseq | -0.6100 | 0.0000 | |
| SRP219564 | ATOX1 | 475 | RNAseq | 0.3341 | 0.3988 | |
| TCGA | ATOX1 | 475 | RNAseq | 0.0911 | 0.2193 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ATOX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATOX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATOX1 | 475 | 1 | 12 | 17 | |
| GSE20123 | ATOX1 | 475 | 1 | 12 | 17 | |
| GSE43470 | ATOX1 | 475 | 2 | 10 | 31 | |
| GSE46452 | ATOX1 | 475 | 0 | 27 | 32 | |
| GSE47630 | ATOX1 | 475 | 0 | 20 | 20 | |
| GSE54993 | ATOX1 | 475 | 9 | 1 | 60 | |
| GSE54994 | ATOX1 | 475 | 2 | 16 | 35 | |
| GSE60625 | ATOX1 | 475 | 0 | 0 | 11 | |
| GSE74703 | ATOX1 | 475 | 2 | 8 | 26 | |
| GSE74704 | ATOX1 | 475 | 1 | 7 | 12 | |
| TCGA | ATOX1 | 475 | 5 | 37 | 54 |
Total number of gains: 23; Total number of losses: 150; Total Number of normals: 315.
Somatic mutations of ATOX1:
Generating mutation plots.
Highly correlated genes for ATOX1:
Showing top 20/391 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATOX1 | C5orf15 | 0.77447 | 3 | 0 | 3 |
| ATOX1 | RPE | 0.760421 | 3 | 0 | 3 |
| ATOX1 | CLDND2 | 0.725001 | 3 | 0 | 3 |
| ATOX1 | MAPK11 | 0.724556 | 3 | 0 | 3 |
| ATOX1 | RARA | 0.707383 | 3 | 0 | 3 |
| ATOX1 | USP32 | 0.689709 | 3 | 0 | 3 |
| ATOX1 | PDZD11 | 0.688923 | 5 | 0 | 3 |
| ATOX1 | SLC35A4 | 0.687539 | 5 | 0 | 5 |
| ATOX1 | CSNK1A1 | 0.687408 | 6 | 0 | 5 |
| ATOX1 | DYNC1I2 | 0.6808 | 5 | 0 | 4 |
| ATOX1 | RNF145 | 0.680727 | 4 | 0 | 3 |
| ATOX1 | PGLS | 0.676305 | 5 | 0 | 4 |
| ATOX1 | CXXC5 | 0.675369 | 6 | 0 | 5 |
| ATOX1 | UBAP1 | 0.673638 | 4 | 0 | 3 |
| ATOX1 | HIPK3 | 0.665367 | 3 | 0 | 3 |
| ATOX1 | LIMK1 | 0.664789 | 3 | 0 | 3 |
| ATOX1 | CISH | 0.664108 | 5 | 0 | 5 |
| ATOX1 | GHITM | 0.663979 | 4 | 0 | 3 |
| ATOX1 | LEPROT | 0.662702 | 4 | 0 | 3 |
| ATOX1 | GMPPB | 0.656196 | 3 | 0 | 3 |
For details and further investigation, click here
