| Full name: ovo like transcriptional repressor 1 | Alias Symbol: HOVO1 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 5017 | HGNC ID: HGNC:8525 | Ensembl Gene: ENSG00000172818 | OMIM ID: 602313 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of OVOL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OVOL1 | 5017 | 229396_at | -0.7431 | 0.3250 | |
| GSE20347 | OVOL1 | 5017 | 206604_at | -0.7686 | 0.0000 | |
| GSE23400 | OVOL1 | 5017 | 206604_at | -0.6484 | 0.0000 | |
| GSE26886 | OVOL1 | 5017 | 229396_at | -2.4409 | 0.0000 | |
| GSE29001 | OVOL1 | 5017 | 206604_at | -0.7141 | 0.0004 | |
| GSE38129 | OVOL1 | 5017 | 206604_at | -0.5014 | 0.0108 | |
| GSE45670 | OVOL1 | 5017 | 229396_at | -0.0317 | 0.9147 | |
| GSE63941 | OVOL1 | 5017 | 229396_at | 2.1452 | 0.0082 | |
| GSE77861 | OVOL1 | 5017 | 229396_at | -0.5773 | 0.1646 | |
| GSE97050 | OVOL1 | 5017 | A_23_P202810 | -0.5498 | 0.4245 | |
| SRP007169 | OVOL1 | 5017 | RNAseq | -2.6711 | 0.0000 | |
| SRP008496 | OVOL1 | 5017 | RNAseq | -2.1561 | 0.0000 | |
| SRP064894 | OVOL1 | 5017 | RNAseq | -1.7770 | 0.0005 | |
| SRP133303 | OVOL1 | 5017 | RNAseq | -1.6321 | 0.0001 | |
| SRP159526 | OVOL1 | 5017 | RNAseq | -2.7233 | 0.0003 | |
| SRP193095 | OVOL1 | 5017 | RNAseq | -0.9778 | 0.0063 | |
| SRP219564 | OVOL1 | 5017 | RNAseq | -2.8393 | 0.0143 | |
| TCGA | OVOL1 | 5017 | RNAseq | 0.6548 | 0.0056 |
Upregulated datasets: 1; Downregulated datasets: 7.
Survival by OVOL1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of OVOL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OVOL1 | 5017 | 8 | 5 | 17 | |
| GSE20123 | OVOL1 | 5017 | 8 | 5 | 17 | |
| GSE43470 | OVOL1 | 5017 | 6 | 1 | 36 | |
| GSE46452 | OVOL1 | 5017 | 11 | 3 | 45 | |
| GSE47630 | OVOL1 | 5017 | 7 | 5 | 28 | |
| GSE54993 | OVOL1 | 5017 | 3 | 0 | 67 | |
| GSE54994 | OVOL1 | 5017 | 7 | 5 | 41 | |
| GSE60625 | OVOL1 | 5017 | 0 | 3 | 8 | |
| GSE74703 | OVOL1 | 5017 | 4 | 0 | 32 | |
| GSE74704 | OVOL1 | 5017 | 6 | 3 | 11 | |
| TCGA | OVOL1 | 5017 | 23 | 7 | 66 |
Total number of gains: 83; Total number of losses: 37; Total Number of normals: 368.
Somatic mutations of OVOL1:
Generating mutation plots.
Highly correlated genes for OVOL1:
Showing top 20/869 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OVOL1 | TGM1 | 0.746071 | 10 | 0 | 9 |
| OVOL1 | GBP6 | 0.745083 | 3 | 0 | 3 |
| OVOL1 | SULT2B1 | 0.728083 | 11 | 0 | 11 |
| OVOL1 | ALOX12 | 0.72021 | 8 | 0 | 8 |
| OVOL1 | EVPL | 0.714177 | 10 | 0 | 9 |
| OVOL1 | TMEM40 | 0.713705 | 11 | 0 | 9 |
| OVOL1 | TGM3 | 0.711871 | 9 | 0 | 9 |
| OVOL1 | CWH43 | 0.710855 | 8 | 0 | 7 |
| OVOL1 | SPINK5 | 0.70901 | 8 | 0 | 8 |
| OVOL1 | CLIC3 | 0.70822 | 10 | 0 | 8 |
| OVOL1 | ENDOU | 0.702898 | 9 | 0 | 9 |
| OVOL1 | SERPINB13 | 0.700672 | 9 | 0 | 8 |
| OVOL1 | TTC22 | 0.70067 | 9 | 0 | 9 |
| OVOL1 | C22orf15 | 0.700164 | 3 | 0 | 3 |
| OVOL1 | MXD1 | 0.698795 | 10 | 0 | 9 |
| OVOL1 | PRDM1 | 0.698501 | 9 | 0 | 8 |
| OVOL1 | IL18 | 0.697982 | 8 | 0 | 7 |
| OVOL1 | ATP10B | 0.697956 | 6 | 0 | 5 |
| OVOL1 | TRIP10 | 0.697248 | 10 | 0 | 9 |
| OVOL1 | PPL | 0.692994 | 10 | 0 | 9 |
For details and further investigation, click here
