AUNIP

 

Full name: aurora kinase A and ninein interacting protein Alias Symbol: MGC2603|AIBp
Type: protein-coding gene Cytoband: 1p36.11
Entrez ID: 79000 HGNC ID: HGNC:28363 Ensembl Gene: ENSG00000127423 OMIM ID: 
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of AUNIP:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AUNIP 79000 220011_at 0.8768 0.0610
GSE20347 AUNIP 79000 220011_at 0.8284 0.0000
GSE23400 AUNIP 79000 220011_at 0.3123 0.0000
GSE26886 AUNIP 79000 220011_at 1.0910 0.0006
GSE29001 AUNIP 79000 220011_at 0.6362 0.0097
GSE38129 AUNIP 79000 220011_at 0.9722 0.0000
GSE45670 AUNIP 79000 220011_at 1.1355 0.0000
GSE53622 AUNIP 79000 85880 1.0652 0.0000
GSE53624 AUNIP 79000 85880 1.4524 0.0000
GSE63941 AUNIP 79000 220011_at 2.6996 0.0000
GSE77861 AUNIP 79000 220011_at 0.3109 0.0861
SRP007169 AUNIP 79000 RNAseq 2.5127 0.0001
SRP008496 AUNIP 79000 RNAseq 1.7464 0.0003
SRP064894 AUNIP 79000 RNAseq 1.5601 0.0000
SRP133303 AUNIP 79000 RNAseq 1.6239 0.0000
SRP159526 AUNIP 79000 RNAseq 2.1570 0.0000
SRP193095 AUNIP 79000 RNAseq 1.4304 0.0000
SRP219564 AUNIP 79000 RNAseq 1.2987 0.0088

Upregulated datasets: 12; Downregulated datasets: 0.  

 

Survival by AUNIP expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of AUNIP:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AUNIP 79000 0 5 25
GSE20123 AUNIP 79000 0 4 26
GSE43470 AUNIP 79000 2 6 35
GSE46452 AUNIP 79000 5 1 53
GSE47630 AUNIP 79000 8 3 29
GSE54993 AUNIP 79000 2 1 67
GSE54994 AUNIP 79000 10 4 39
GSE60625 AUNIP 79000 0 0 11
GSE74703 AUNIP 79000 1 4 31
GSE74704 AUNIP 79000 0 0 20
TCGA AUNIP 79000 9 24 63

Total number of gains: 37; Total number of losses: 52; Total Number of normals: 399.  

 

Somatic mutations of AUNIP:

 

Generating mutation plots.

 

Highly correlated genes for AUNIP:

 

Showing top 20/1538 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AUNIPTRIP130.78328411011
AUNIPCDCA50.778568707
AUNIPUBE2T0.768707
AUNIPKNSTRN0.76557707
AUNIPSTIL0.762671009
AUNIPORC60.75768211010
AUNIPCDCA80.75758510010
AUNIPKIF2C0.75625711010
AUNIPKIF140.75566210010
AUNIPGINS10.7516711011
AUNIPMCM80.746517707
AUNIPNTMT10.746068505
AUNIPWDHD10.74370910010
AUNIPTROAP0.74111310010
AUNIPMTFR20.740891707
AUNIPBLM0.74028411010
AUNIPCEP550.73993710010
AUNIPPKMYT10.738515909
AUNIPCDC200.7364671009
AUNIPUHRF10.733783707

For details and further investigation, click here