| Full name: Fc fragment of IgE receptor II | Alias Symbol: CLEC4J|CD23 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 2208 | HGNC ID: HGNC:3612 | Ensembl Gene: ENSG00000104921 | OMIM ID: 151445 |
| Drug and gene relationship at DGIdb | |||
FCER2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05169 | Epstein-Barr virus infection |
Expression of FCER2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCER2 | 2208 | 206760_s_at | -0.0853 | 0.8536 | |
| GSE20347 | FCER2 | 2208 | 206759_at | -0.0992 | 0.1327 | |
| GSE23400 | FCER2 | 2208 | 206760_s_at | -0.1791 | 0.0000 | |
| GSE26886 | FCER2 | 2208 | 206760_s_at | 0.0544 | 0.7463 | |
| GSE29001 | FCER2 | 2208 | 206760_s_at | -0.1529 | 0.3125 | |
| GSE38129 | FCER2 | 2208 | 206759_at | -0.1128 | 0.2352 | |
| GSE45670 | FCER2 | 2208 | 206760_s_at | -0.0742 | 0.4261 | |
| GSE53622 | FCER2 | 2208 | 115374 | -0.7503 | 0.0000 | |
| GSE53624 | FCER2 | 2208 | 115374 | -0.8984 | 0.0000 | |
| GSE63941 | FCER2 | 2208 | 206759_at | 0.1026 | 0.5417 | |
| GSE77861 | FCER2 | 2208 | 206760_s_at | -0.3843 | 0.0039 | |
| GSE97050 | FCER2 | 2208 | A_23_P164773 | -0.0560 | 0.8918 | |
| TCGA | FCER2 | 2208 | RNAseq | -1.3987 | 0.1088 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FCER2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCER2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCER2 | 2208 | 5 | 3 | 22 | |
| GSE20123 | FCER2 | 2208 | 4 | 2 | 24 | |
| GSE43470 | FCER2 | 2208 | 2 | 6 | 35 | |
| GSE46452 | FCER2 | 2208 | 47 | 1 | 11 | |
| GSE47630 | FCER2 | 2208 | 5 | 7 | 28 | |
| GSE54993 | FCER2 | 2208 | 16 | 3 | 51 | |
| GSE54994 | FCER2 | 2208 | 6 | 13 | 34 | |
| GSE60625 | FCER2 | 2208 | 9 | 0 | 2 | |
| GSE74703 | FCER2 | 2208 | 2 | 4 | 30 | |
| GSE74704 | FCER2 | 2208 | 1 | 2 | 17 | |
| TCGA | FCER2 | 2208 | 9 | 20 | 67 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of FCER2:
Generating mutation plots.
Highly correlated genes for FCER2:
Showing top 20/546 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCER2 | MAPK11 | 0.708515 | 3 | 0 | 3 |
| FCER2 | PANX2 | 0.706239 | 3 | 0 | 3 |
| FCER2 | FCRLA | 0.67722 | 4 | 0 | 3 |
| FCER2 | ARHGEF6 | 0.674676 | 3 | 0 | 3 |
| FCER2 | TCL6 | 0.67316 | 4 | 0 | 4 |
| FCER2 | FLI1 | 0.669551 | 4 | 0 | 4 |
| FCER2 | ETS1 | 0.669374 | 4 | 0 | 4 |
| FCER2 | CCDC36 | 0.667936 | 3 | 0 | 3 |
| FCER2 | CXCR6 | 0.664763 | 4 | 0 | 4 |
| FCER2 | TAAR5 | 0.66119 | 4 | 0 | 3 |
| FCER2 | TNFAIP8L2 | 0.658081 | 3 | 0 | 3 |
| FCER2 | DHDDS | 0.656726 | 4 | 0 | 3 |
| FCER2 | FMN1 | 0.655074 | 3 | 0 | 3 |
| FCER2 | SH2D3C | 0.652298 | 5 | 0 | 4 |
| FCER2 | CLC | 0.652041 | 4 | 0 | 4 |
| FCER2 | TMEM200C | 0.650928 | 3 | 0 | 3 |
| FCER2 | CCDC87 | 0.647511 | 3 | 0 | 3 |
| FCER2 | SHB | 0.644279 | 3 | 0 | 3 |
| FCER2 | DNMT3L | 0.642604 | 3 | 0 | 3 |
| FCER2 | RABEP2 | 0.63977 | 5 | 0 | 5 |
For details and further investigation, click here
