| Full name: proline, glutamate and leucine rich protein 1 | Alias Symbol: MNAR | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 27043 | HGNC ID: HGNC:30134 | Ensembl Gene: ENSG00000141456 | OMIM ID: 609455 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PELP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PELP1 | 27043 | 215354_s_at | 0.5142 | 0.2254 | |
| GSE20347 | PELP1 | 27043 | 215354_s_at | 0.5148 | 0.0001 | |
| GSE23400 | PELP1 | 27043 | 215354_s_at | 0.1550 | 0.0001 | |
| GSE26886 | PELP1 | 27043 | 215354_s_at | 1.4255 | 0.0000 | |
| GSE29001 | PELP1 | 27043 | 215354_s_at | 0.2931 | 0.0808 | |
| GSE38129 | PELP1 | 27043 | 215354_s_at | 0.4806 | 0.0000 | |
| GSE45670 | PELP1 | 27043 | 215354_s_at | 0.2111 | 0.0588 | |
| GSE53622 | PELP1 | 27043 | 17783 | 0.3136 | 0.0000 | |
| GSE53624 | PELP1 | 27043 | 17783 | 0.6802 | 0.0000 | |
| GSE63941 | PELP1 | 27043 | 215354_s_at | 0.4892 | 0.0499 | |
| GSE77861 | PELP1 | 27043 | 215354_s_at | 0.0841 | 0.5265 | |
| GSE97050 | PELP1 | 27043 | A_33_P3659808 | 0.2136 | 0.2935 | |
| SRP007169 | PELP1 | 27043 | RNAseq | 1.3077 | 0.0103 | |
| SRP008496 | PELP1 | 27043 | RNAseq | 1.0101 | 0.0151 | |
| SRP064894 | PELP1 | 27043 | RNAseq | 0.8551 | 0.0011 | |
| SRP133303 | PELP1 | 27043 | RNAseq | 0.1538 | 0.2437 | |
| SRP159526 | PELP1 | 27043 | RNAseq | 1.0216 | 0.0074 | |
| SRP193095 | PELP1 | 27043 | RNAseq | 0.8044 | 0.0000 | |
| SRP219564 | PELP1 | 27043 | RNAseq | 1.2214 | 0.0299 | |
| TCGA | PELP1 | 27043 | RNAseq | 0.1077 | 0.0228 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by PELP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PELP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PELP1 | 27043 | 5 | 2 | 23 | |
| GSE20123 | PELP1 | 27043 | 5 | 3 | 22 | |
| GSE43470 | PELP1 | 27043 | 1 | 6 | 36 | |
| GSE46452 | PELP1 | 27043 | 34 | 1 | 24 | |
| GSE47630 | PELP1 | 27043 | 7 | 1 | 32 | |
| GSE54993 | PELP1 | 27043 | 4 | 3 | 63 | |
| GSE54994 | PELP1 | 27043 | 5 | 9 | 39 | |
| GSE60625 | PELP1 | 27043 | 4 | 0 | 7 | |
| GSE74703 | PELP1 | 27043 | 1 | 3 | 32 | |
| GSE74704 | PELP1 | 27043 | 3 | 1 | 16 | |
| TCGA | PELP1 | 27043 | 19 | 21 | 56 |
Total number of gains: 88; Total number of losses: 50; Total Number of normals: 350.
Somatic mutations of PELP1:
Generating mutation plots.
Highly correlated genes for PELP1:
Showing top 20/1319 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PELP1 | HNRNPUL1 | 0.803997 | 3 | 0 | 3 |
| PELP1 | DAPK3 | 0.774258 | 3 | 0 | 3 |
| PELP1 | NACC1 | 0.76519 | 4 | 0 | 4 |
| PELP1 | IRF9 | 0.758112 | 3 | 0 | 3 |
| PELP1 | SORBS3 | 0.753783 | 3 | 0 | 3 |
| PELP1 | SLC2A3 | 0.753022 | 3 | 0 | 3 |
| PELP1 | TSHR | 0.748378 | 3 | 0 | 3 |
| PELP1 | SFR1 | 0.744378 | 3 | 0 | 3 |
| PELP1 | FZR1 | 0.742497 | 3 | 0 | 3 |
| PELP1 | ROMO1 | 0.734176 | 3 | 0 | 3 |
| PELP1 | ZNF680 | 0.729477 | 3 | 0 | 3 |
| PELP1 | ALKBH6 | 0.721276 | 5 | 0 | 3 |
| PELP1 | SLC39A3 | 0.718264 | 5 | 0 | 5 |
| PELP1 | WDR54 | 0.713297 | 5 | 0 | 5 |
| PELP1 | NEK3 | 0.713271 | 3 | 0 | 3 |
| PELP1 | SLC26A11 | 0.713071 | 4 | 0 | 4 |
| PELP1 | CELF1 | 0.712356 | 5 | 0 | 4 |
| PELP1 | ACBD6 | 0.711883 | 4 | 0 | 3 |
| PELP1 | PACSIN3 | 0.711664 | 3 | 0 | 3 |
| PELP1 | TRPC1 | 0.707796 | 3 | 0 | 3 |
For details and further investigation, click here
