PHF19

 

Full name: PHD finger protein 19 Alias Symbol: DKFZP727G051|PCL3|MTF2L1|TDRD19B
Type: protein-coding gene Cytoband: 9q33.2
Entrez ID: 26147 HGNC ID: HGNC:24566 Ensembl Gene: ENSG00000119403 OMIM ID: 609740
Drug and gene relationship at DGIdb

 

Expression of PHF19:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PHF19 26147 227212_s_at 0.0378 0.9517
GSE26886 PHF19 26147 227211_at 1.0814 0.0010
GSE45670 PHF19 26147 227211_at 0.3025 0.2737
GSE53622 PHF19 26147 34953 0.5115 0.0000
GSE53624 PHF19 26147 34953 0.7697 0.0000
GSE63941 PHF19 26147 227212_s_at 0.6587 0.3253
GSE77861 PHF19 26147 227211_at 0.0274 0.9031
GSE97050 PHF19 26147 A_23_P21436 -0.1116 0.7590
SRP007169 PHF19 26147 RNAseq 1.0339 0.0038
SRP008496 PHF19 26147 RNAseq 0.7610 0.0165
SRP064894 PHF19 26147 RNAseq 1.0483 0.0009
SRP133303 PHF19 26147 RNAseq 0.1471 0.4467
SRP159526 PHF19 26147 RNAseq 0.3106 0.3555
SRP193095 PHF19 26147 RNAseq 0.5452 0.0002
SRP219564 PHF19 26147 RNAseq 0.2269 0.4960
TCGA PHF19 26147 RNAseq 0.1058 0.1381

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by PHF19 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PHF19:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PHF19 26147 3 7 20
GSE20123 PHF19 26147 3 7 20
GSE43470 PHF19 26147 5 4 34
GSE46452 PHF19 26147 6 13 40
GSE47630 PHF19 26147 3 16 21
GSE54993 PHF19 26147 3 3 64
GSE54994 PHF19 26147 9 10 34
GSE60625 PHF19 26147 0 0 11
GSE74703 PHF19 26147 5 3 28
GSE74704 PHF19 26147 2 5 13
TCGA PHF19 26147 27 26 43

Total number of gains: 66; Total number of losses: 94; Total Number of normals: 328.  


 

Somatic mutations of PHF19:

 

Generating mutation plots.

 

Highly correlated genes for PHF19:

 

Showing top 20/443 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PHF19DOCK110.752301303
PHF19PEAR10.707152303
PHF19HMCN10.704947303
PHF19RHOBTB20.681607404
PHF19MCM60.681441505
PHF19WDHD10.679228504
PHF19IL3RA0.679192303
PHF19ACTN10.670522504
PHF19NTMT10.667456404
PHF19MCAM0.664622303
PHF19DTYMK0.663956505
PHF19OLFML2A0.661584303
PHF19CENPN0.659557505
PHF19TWIST20.657679303
PHF19BIRC50.650869505
PHF19CKAP2L0.650771505
PHF19PRR110.650316404
PHF19CRISPLD20.648601303
PHF19JDP20.648411303
PHF19PDPN0.647327404

For details and further investigation, click here