| Full name: pancreatic lipase | Alias Symbol: PL | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 5406 | HGNC ID: HGNC:9155 | Ensembl Gene: ENSG00000175535 | OMIM ID: 246600 |
| Drug and gene relationship at DGIdb | |||
Expression of PNLIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNLIP | 5406 | 205912_at | -0.1322 | 0.6532 | |
| GSE20347 | PNLIP | 5406 | 205912_at | -0.0443 | 0.3802 | |
| GSE23400 | PNLIP | 5406 | 205912_at | -0.1973 | 0.0340 | |
| GSE26886 | PNLIP | 5406 | 205912_at | -0.0332 | 0.7434 | |
| GSE29001 | PNLIP | 5406 | 205912_at | -0.0635 | 0.6067 | |
| GSE38129 | PNLIP | 5406 | 205912_at | -0.0885 | 0.0477 | |
| GSE45670 | PNLIP | 5406 | 205912_at | -0.0105 | 0.9170 | |
| GSE53622 | PNLIP | 5406 | 21453 | -0.5700 | 0.0072 | |
| GSE53624 | PNLIP | 5406 | 21453 | -1.0539 | 0.0000 | |
| GSE63941 | PNLIP | 5406 | 205912_at | 0.1431 | 0.2193 | |
| GSE77861 | PNLIP | 5406 | 205912_at | -0.1677 | 0.0513 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PNLIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNLIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNLIP | 5406 | 1 | 7 | 22 | |
| GSE20123 | PNLIP | 5406 | 1 | 7 | 22 | |
| GSE43470 | PNLIP | 5406 | 0 | 9 | 34 | |
| GSE46452 | PNLIP | 5406 | 0 | 11 | 48 | |
| GSE47630 | PNLIP | 5406 | 2 | 14 | 24 | |
| GSE54993 | PNLIP | 5406 | 8 | 0 | 62 | |
| GSE54994 | PNLIP | 5406 | 1 | 9 | 43 | |
| GSE60625 | PNLIP | 5406 | 0 | 0 | 11 | |
| GSE74703 | PNLIP | 5406 | 0 | 6 | 30 | |
| GSE74704 | PNLIP | 5406 | 1 | 3 | 16 | |
| TCGA | PNLIP | 5406 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 94; Total Number of normals: 376.
Somatic mutations of PNLIP:
Generating mutation plots.
Highly correlated genes for PNLIP:
Showing top 20/197 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNLIP | MAP1A | 0.706582 | 3 | 0 | 3 |
| PNLIP | SLC13A3 | 0.691788 | 3 | 0 | 3 |
| PNLIP | TERT | 0.680725 | 3 | 0 | 3 |
| PNLIP | SLC2A4 | 0.674359 | 3 | 0 | 3 |
| PNLIP | OBP2A | 0.672475 | 3 | 0 | 3 |
| PNLIP | NAALADL1 | 0.670442 | 3 | 0 | 3 |
| PNLIP | STMN2 | 0.669921 | 3 | 0 | 3 |
| PNLIP | INSRR | 0.66968 | 3 | 0 | 3 |
| PNLIP | ZNF358 | 0.669084 | 3 | 0 | 3 |
| PNLIP | FAM47C | 0.661434 | 3 | 0 | 3 |
| PNLIP | TFF1 | 0.653413 | 3 | 0 | 3 |
| PNLIP | LGI2 | 0.652186 | 3 | 0 | 3 |
| PNLIP | PGM5 | 0.650418 | 3 | 0 | 3 |
| PNLIP | IFNA10 | 0.640535 | 4 | 0 | 4 |
| PNLIP | NPR1 | 0.640247 | 4 | 0 | 3 |
| PNLIP | CLEC1B | 0.637703 | 3 | 0 | 3 |
| PNLIP | PDZD7 | 0.636726 | 5 | 0 | 5 |
| PNLIP | KCNK2 | 0.635674 | 3 | 0 | 3 |
| PNLIP | EPHA3 | 0.634143 | 3 | 0 | 3 |
| PNLIP | LIMS2 | 0.633729 | 3 | 0 | 3 |
For details and further investigation, click here
