| Full name: spermine oxidase | Alias Symbol: FLJ20746|dJ779E11.1|PAO|PAOh1|MGC1010|SMO | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 54498 | HGNC ID: HGNC:15862 | Ensembl Gene: ENSG00000088826 | OMIM ID: 615854 |
| Drug and gene relationship at DGIdb | |||
Expression of SMOX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMOX | 54498 | 210357_s_at | 0.4176 | 0.5181 | |
| GSE20347 | SMOX | 54498 | 210357_s_at | 0.1654 | 0.4237 | |
| GSE23400 | SMOX | 54498 | 210357_s_at | -0.1292 | 0.0381 | |
| GSE26886 | SMOX | 54498 | 210357_s_at | 0.4269 | 0.1322 | |
| GSE29001 | SMOX | 54498 | 210357_s_at | -0.3265 | 0.2567 | |
| GSE38129 | SMOX | 54498 | 210357_s_at | 0.2490 | 0.0875 | |
| GSE45670 | SMOX | 54498 | 210357_s_at | 0.1965 | 0.1646 | |
| GSE53622 | SMOX | 54498 | 33950 | 0.4281 | 0.0116 | |
| GSE53624 | SMOX | 54498 | 33950 | 0.1600 | 0.1854 | |
| GSE63941 | SMOX | 54498 | 210357_s_at | 0.1840 | 0.7791 | |
| GSE77861 | SMOX | 54498 | 210357_s_at | 0.3004 | 0.2009 | |
| GSE97050 | SMOX | 54498 | A_23_P102731 | 0.7369 | 0.1399 | |
| SRP007169 | SMOX | 54498 | RNAseq | -2.2548 | 0.0001 | |
| SRP008496 | SMOX | 54498 | RNAseq | -2.1276 | 0.0000 | |
| SRP064894 | SMOX | 54498 | RNAseq | -0.3656 | 0.2784 | |
| SRP133303 | SMOX | 54498 | RNAseq | -0.0388 | 0.8949 | |
| SRP159526 | SMOX | 54498 | RNAseq | 1.6741 | 0.0018 | |
| SRP193095 | SMOX | 54498 | RNAseq | -0.0333 | 0.8811 | |
| SRP219564 | SMOX | 54498 | RNAseq | 0.7231 | 0.2838 | |
| TCGA | SMOX | 54498 | RNAseq | -0.0867 | 0.3974 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by SMOX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMOX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMOX | 54498 | 13 | 3 | 14 | |
| GSE20123 | SMOX | 54498 | 14 | 3 | 13 | |
| GSE43470 | SMOX | 54498 | 10 | 1 | 32 | |
| GSE46452 | SMOX | 54498 | 26 | 1 | 32 | |
| GSE47630 | SMOX | 54498 | 18 | 4 | 18 | |
| GSE54993 | SMOX | 54498 | 2 | 14 | 54 | |
| GSE54994 | SMOX | 54498 | 24 | 2 | 27 | |
| GSE60625 | SMOX | 54498 | 0 | 0 | 11 | |
| GSE74703 | SMOX | 54498 | 9 | 1 | 26 | |
| GSE74704 | SMOX | 54498 | 9 | 1 | 10 | |
| TCGA | SMOX | 54498 | 39 | 11 | 46 |
Total number of gains: 164; Total number of losses: 41; Total Number of normals: 283.
Somatic mutations of SMOX:
Generating mutation plots.
Highly correlated genes for SMOX:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMOX | ERCC4 | 0.7794 | 3 | 0 | 3 |
| SMOX | PCSK1 | 0.767796 | 3 | 0 | 3 |
| SMOX | CD19 | 0.719494 | 3 | 0 | 3 |
| SMOX | GEMIN5 | 0.714049 | 3 | 0 | 3 |
| SMOX | UTP15 | 0.710821 | 3 | 0 | 3 |
| SMOX | IL18BP | 0.705057 | 3 | 0 | 3 |
| SMOX | SUSD1 | 0.695695 | 3 | 0 | 3 |
| SMOX | PNMA1 | 0.684701 | 3 | 0 | 3 |
| SMOX | CENPH | 0.682637 | 3 | 0 | 3 |
| SMOX | UBR4 | 0.681173 | 3 | 0 | 3 |
| SMOX | SLC15A4 | 0.677158 | 3 | 0 | 3 |
| SMOX | CDC14A | 0.671558 | 3 | 0 | 3 |
| SMOX | CD5 | 0.6653 | 3 | 0 | 3 |
| SMOX | DENND4B | 0.65775 | 3 | 0 | 3 |
| SMOX | EFR3B | 0.651751 | 3 | 0 | 3 |
| SMOX | TRPC6 | 0.640814 | 3 | 0 | 3 |
| SMOX | EHD1 | 0.637485 | 4 | 0 | 3 |
| SMOX | GPR135 | 0.63653 | 3 | 0 | 3 |
| SMOX | EPN1 | 0.635332 | 4 | 0 | 3 |
| SMOX | USP5 | 0.633513 | 4 | 0 | 4 |
For details and further investigation, click here
