| Full name: popeye domain containing 3 | Alias Symbol: POP3|MGC22671|bA355M14.1 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 64208 | HGNC ID: HGNC:17649 | Ensembl Gene: ENSG00000132429 | OMIM ID: 605824 |
| Drug and gene relationship at DGIdb | |||
Expression of POPDC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POPDC3 | 64208 | 219926_at | 1.5665 | 0.2909 | |
| GSE20347 | POPDC3 | 64208 | 219926_at | 1.5683 | 0.0010 | |
| GSE23400 | POPDC3 | 64208 | 219926_at | 0.4857 | 0.0000 | |
| GSE26886 | POPDC3 | 64208 | 219926_at | 1.9276 | 0.0021 | |
| GSE29001 | POPDC3 | 64208 | 219926_at | 1.7265 | 0.0018 | |
| GSE38129 | POPDC3 | 64208 | 219926_at | 1.6345 | 0.0000 | |
| GSE45670 | POPDC3 | 64208 | 219926_at | 2.1808 | 0.0028 | |
| GSE53622 | POPDC3 | 64208 | 90603 | 3.0552 | 0.0000 | |
| GSE53624 | POPDC3 | 64208 | 90603 | 4.4128 | 0.0000 | |
| GSE63941 | POPDC3 | 64208 | 219926_at | -0.8942 | 0.5929 | |
| GSE77861 | POPDC3 | 64208 | 219926_at | 1.3207 | 0.0495 | |
| GSE97050 | POPDC3 | 64208 | A_23_P358597 | 0.8881 | 0.3713 | |
| SRP133303 | POPDC3 | 64208 | RNAseq | 3.3558 | 0.0000 | |
| SRP159526 | POPDC3 | 64208 | RNAseq | 3.5601 | 0.0000 | |
| SRP219564 | POPDC3 | 64208 | RNAseq | 1.9049 | 0.0059 | |
| TCGA | POPDC3 | 64208 | RNAseq | 0.3938 | 0.3677 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by POPDC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POPDC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POPDC3 | 64208 | 3 | 3 | 24 | |
| GSE20123 | POPDC3 | 64208 | 3 | 2 | 25 | |
| GSE43470 | POPDC3 | 64208 | 3 | 1 | 39 | |
| GSE46452 | POPDC3 | 64208 | 2 | 11 | 46 | |
| GSE47630 | POPDC3 | 64208 | 8 | 5 | 27 | |
| GSE54993 | POPDC3 | 64208 | 3 | 2 | 65 | |
| GSE54994 | POPDC3 | 64208 | 8 | 8 | 37 | |
| GSE60625 | POPDC3 | 64208 | 0 | 2 | 9 | |
| GSE74703 | POPDC3 | 64208 | 2 | 1 | 33 | |
| GSE74704 | POPDC3 | 64208 | 1 | 0 | 19 | |
| TCGA | POPDC3 | 64208 | 7 | 25 | 64 |
Total number of gains: 40; Total number of losses: 60; Total Number of normals: 388.
Somatic mutations of POPDC3:
Generating mutation plots.
Highly correlated genes for POPDC3:
Showing top 20/1511 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POPDC3 | EXOSC6 | 0.735554 | 3 | 0 | 3 |
| POPDC3 | RAPH1 | 0.732595 | 3 | 0 | 3 |
| POPDC3 | CENPH | 0.731168 | 4 | 0 | 4 |
| POPDC3 | XPR1 | 0.716395 | 7 | 0 | 7 |
| POPDC3 | BLACAT1 | 0.715407 | 4 | 0 | 4 |
| POPDC3 | TENM2 | 0.708647 | 6 | 0 | 6 |
| POPDC3 | FADS1 | 0.708275 | 3 | 0 | 3 |
| POPDC3 | C14orf119 | 0.706366 | 3 | 0 | 3 |
| POPDC3 | ZIC5 | 0.701988 | 4 | 0 | 4 |
| POPDC3 | ZNF469 | 0.700449 | 6 | 0 | 6 |
| POPDC3 | ANLN | 0.699328 | 6 | 0 | 6 |
| POPDC3 | HOMER3 | 0.699023 | 10 | 0 | 10 |
| POPDC3 | FMNL2 | 0.698061 | 7 | 0 | 7 |
| POPDC3 | TMEM17 | 0.696876 | 5 | 0 | 4 |
| POPDC3 | MRPL21 | 0.696817 | 4 | 0 | 3 |
| POPDC3 | ELOVL7 | 0.695758 | 3 | 0 | 3 |
| POPDC3 | C16orf74 | 0.692586 | 7 | 0 | 7 |
| POPDC3 | YWHAG | 0.688562 | 5 | 0 | 5 |
| POPDC3 | MAPK12 | 0.687587 | 7 | 0 | 6 |
| POPDC3 | FAM89A | 0.686901 | 3 | 0 | 3 |
For details and further investigation, click here
