PPM1G

 

Full name: protein phosphatase, Mg2+/Mn2+ dependent 1G Alias Symbol: PP2CG|PP2Cgamma
Type: protein-coding gene Cytoband: 2p23.3
Entrez ID: 5496 HGNC ID: HGNC:9278 Ensembl Gene: ENSG00000115241 OMIM ID: 605119
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of PPM1G:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PPM1G 5496 200913_at 0.6007 0.1956
GSE20347 PPM1G 5496 200913_at 0.2752 0.1046
GSE23400 PPM1G 5496 200913_at 0.2741 0.0000
GSE26886 PPM1G 5496 200913_at 0.0178 0.9347
GSE29001 PPM1G 5496 200913_at 0.0389 0.9228
GSE38129 PPM1G 5496 200913_at 0.5405 0.0000
GSE45670 PPM1G 5496 200913_at 0.4914 0.0045
GSE53622 PPM1G 5496 90577 0.4723 0.0000
GSE53624 PPM1G 5496 90577 0.5080 0.0000
GSE63941 PPM1G 5496 200913_at 0.4282 0.2379
GSE77861 PPM1G 5496 200913_at 0.4662 0.0122
GSE97050 PPM1G 5496 A_23_P209477 0.4683 0.1923
SRP007169 PPM1G 5496 RNAseq -0.2445 0.6251
SRP008496 PPM1G 5496 RNAseq -0.0898 0.7377
SRP064894 PPM1G 5496 RNAseq 0.2640 0.1334
SRP133303 PPM1G 5496 RNAseq 0.5133 0.0027
SRP159526 PPM1G 5496 RNAseq 0.4280 0.0103
SRP193095 PPM1G 5496 RNAseq 0.3546 0.0137
SRP219564 PPM1G 5496 RNAseq 0.2067 0.5476
TCGA PPM1G 5496 RNAseq 0.1899 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PPM1G expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PPM1G:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PPM1G 5496 11 2 17
GSE20123 PPM1G 5496 11 2 17
GSE43470 PPM1G 5496 3 1 39
GSE46452 PPM1G 5496 2 4 53
GSE47630 PPM1G 5496 8 0 32
GSE54993 PPM1G 5496 0 6 64
GSE54994 PPM1G 5496 10 0 43
GSE60625 PPM1G 5496 0 3 8
GSE74703 PPM1G 5496 3 0 33
GSE74704 PPM1G 5496 9 1 10
TCGA PPM1G 5496 36 2 58

Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.  

 

Somatic mutations of PPM1G:

 

Generating mutation plots.

 

Highly correlated genes for PPM1G:

 

Showing top 20/969 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PPM1GCAD0.71383211011
PPM1GCENPW0.698775505
PPM1GRAD510.683408808
PPM1GTUBG10.68138112011
PPM1GCENPA0.6807771009
PPM1GCDC60.666989706
PPM1GCDC200.666171908
PPM1GDCBLD10.665711605
PPM1GCEP550.6646161009
PPM1GRNASEH2A0.66393311010
PPM1GCDCA50.663903605
PPM1GBIRC50.663811008
PPM1GPSMG30.66107606
PPM1GCDC450.66095810010
PPM1GMRPL40.658315706
PPM1GCHAF1A0.6582951008
PPM1GCCT70.65431209
PPM1GCMIP0.652852505
PPM1GSNRPB0.650991008
PPM1GTRIP130.6504731008

For details and further investigation, click here