| Full name: chaperonin containing TCP1 subunit 7 | Alias Symbol: Ccth|Nip7-1 | ||
| Type: protein-coding gene | Cytoband: 2p13.2 | ||
| Entrez ID: 10574 | HGNC ID: HGNC:1622 | Ensembl Gene: ENSG00000135624 | OMIM ID: 605140 |
| Drug and gene relationship at DGIdb | |||
Expression of CCT7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCT7 | 10574 | 200812_at | 0.3494 | 0.2208 | |
| GSE20347 | CCT7 | 10574 | 200812_at | 0.4361 | 0.0280 | |
| GSE23400 | CCT7 | 10574 | 200812_at | 0.4910 | 0.0000 | |
| GSE26886 | CCT7 | 10574 | 200812_at | 0.1599 | 0.2418 | |
| GSE29001 | CCT7 | 10574 | 200812_at | 0.1592 | 0.7701 | |
| GSE38129 | CCT7 | 10574 | 200812_at | 0.5988 | 0.0000 | |
| GSE45670 | CCT7 | 10574 | 200812_at | 0.3228 | 0.0369 | |
| GSE53622 | CCT7 | 10574 | 47789 | 0.5239 | 0.0000 | |
| GSE53624 | CCT7 | 10574 | 47789 | 0.6528 | 0.0000 | |
| GSE63941 | CCT7 | 10574 | 200812_at | 0.2888 | 0.4520 | |
| GSE77861 | CCT7 | 10574 | 200812_at | 0.6225 | 0.0015 | |
| GSE97050 | CCT7 | 10574 | A_23_P102404 | 0.3969 | 0.1740 | |
| SRP007169 | CCT7 | 10574 | RNAseq | 0.3198 | 0.3265 | |
| SRP008496 | CCT7 | 10574 | RNAseq | 0.3210 | 0.1109 | |
| SRP064894 | CCT7 | 10574 | RNAseq | 0.5030 | 0.0130 | |
| SRP133303 | CCT7 | 10574 | RNAseq | 0.6237 | 0.0000 | |
| SRP159526 | CCT7 | 10574 | RNAseq | 0.9863 | 0.0000 | |
| SRP193095 | CCT7 | 10574 | RNAseq | 0.2554 | 0.0486 | |
| SRP219564 | CCT7 | 10574 | RNAseq | 0.4442 | 0.2203 | |
| TCGA | CCT7 | 10574 | RNAseq | 0.1544 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCT7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCT7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCT7 | 10574 | 11 | 1 | 18 | |
| GSE20123 | CCT7 | 10574 | 11 | 1 | 18 | |
| GSE43470 | CCT7 | 10574 | 4 | 0 | 39 | |
| GSE46452 | CCT7 | 10574 | 2 | 3 | 54 | |
| GSE47630 | CCT7 | 10574 | 7 | 0 | 33 | |
| GSE54993 | CCT7 | 10574 | 0 | 6 | 64 | |
| GSE54994 | CCT7 | 10574 | 11 | 0 | 42 | |
| GSE60625 | CCT7 | 10574 | 0 | 3 | 8 | |
| GSE74703 | CCT7 | 10574 | 4 | 0 | 32 | |
| GSE74704 | CCT7 | 10574 | 9 | 0 | 11 | |
| TCGA | CCT7 | 10574 | 38 | 2 | 56 |
Total number of gains: 97; Total number of losses: 16; Total Number of normals: 375.
Somatic mutations of CCT7:
Generating mutation plots.
Highly correlated genes for CCT7:
Showing top 20/1291 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCT7 | CDC6 | 0.784334 | 6 | 0 | 6 |
| CCT7 | CCT4 | 0.748994 | 12 | 0 | 10 |
| CCT7 | IMP4 | 0.732483 | 10 | 0 | 10 |
| CCT7 | PSMD11 | 0.721975 | 10 | 0 | 10 |
| CCT7 | XPR1 | 0.721169 | 5 | 0 | 5 |
| CCT7 | TK1 | 0.716591 | 10 | 0 | 9 |
| CCT7 | TTL | 0.715412 | 5 | 0 | 5 |
| CCT7 | NTMT1 | 0.714128 | 6 | 0 | 6 |
| CCT7 | KNSTRN | 0.710423 | 6 | 0 | 5 |
| CCT7 | TUBG1 | 0.709451 | 10 | 0 | 9 |
| CCT7 | RANBP1 | 0.709288 | 11 | 0 | 10 |
| CCT7 | NME1 | 0.70767 | 11 | 0 | 10 |
| CCT7 | ADSL | 0.705787 | 9 | 0 | 9 |
| CCT7 | PSMB3 | 0.70441 | 11 | 0 | 9 |
| CCT7 | DGUOK | 0.704275 | 10 | 0 | 9 |
| CCT7 | NUP93 | 0.699172 | 10 | 0 | 10 |
| CCT7 | BOP1 | 0.694358 | 3 | 0 | 3 |
| CCT7 | CDT1 | 0.693435 | 9 | 0 | 9 |
| CCT7 | MSH6 | 0.693429 | 10 | 0 | 9 |
| CCT7 | COA6 | 0.692784 | 5 | 0 | 5 |
For details and further investigation, click here
