CHAF1A

 

Full name: chromatin assembly factor 1 subunit A Alias Symbol: CAF1P150|CAF1B|CAF-1|CAF1|P150|MGC71229
Type: protein-coding gene Cytoband: 19p13.3
Entrez ID: 10036 HGNC ID: HGNC:1910 Ensembl Gene: ENSG00000167670 OMIM ID: 601246
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CHAF1A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CHAF1A 10036 203975_s_at 0.8343 0.1173
GSE20347 CHAF1A 10036 214426_x_at 0.5617 0.0001
GSE23400 CHAF1A 10036 214426_x_at 0.3711 0.0000
GSE26886 CHAF1A 10036 214426_x_at 0.7938 0.0001
GSE29001 CHAF1A 10036 214426_x_at 0.5289 0.0190
GSE38129 CHAF1A 10036 203975_s_at 0.7772 0.0000
GSE45670 CHAF1A 10036 214426_x_at 0.5932 0.0001
GSE53622 CHAF1A 10036 126868 0.7531 0.0000
GSE53624 CHAF1A 10036 126868 1.1008 0.0000
GSE63941 CHAF1A 10036 214426_x_at 1.6506 0.0000
GSE77861 CHAF1A 10036 214426_x_at 0.6405 0.0058
GSE97050 CHAF1A 10036 A_33_P3416366 0.6828 0.1805
SRP007169 CHAF1A 10036 RNAseq 2.1832 0.0020
SRP064894 CHAF1A 10036 RNAseq 0.7781 0.0022
SRP133303 CHAF1A 10036 RNAseq 0.7095 0.0169
SRP159526 CHAF1A 10036 RNAseq 0.9701 0.0003
SRP193095 CHAF1A 10036 RNAseq 0.7988 0.0000
SRP219564 CHAF1A 10036 RNAseq 1.0032 0.0032
TCGA CHAF1A 10036 RNAseq 0.5308 0.0000

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by CHAF1A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CHAF1A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CHAF1A 10036 5 3 22
GSE20123 CHAF1A 10036 4 2 24
GSE43470 CHAF1A 10036 1 8 34
GSE46452 CHAF1A 10036 47 1 11
GSE47630 CHAF1A 10036 5 7 28
GSE54993 CHAF1A 10036 16 3 51
GSE54994 CHAF1A 10036 6 16 31
GSE60625 CHAF1A 10036 9 0 2
GSE74703 CHAF1A 10036 1 5 30
GSE74704 CHAF1A 10036 1 2 17
TCGA CHAF1A 10036 12 18 66

Total number of gains: 107; Total number of losses: 65; Total Number of normals: 316.  

 

Somatic mutations of CHAF1A:

 

Generating mutation plots.

 

Highly correlated genes for CHAF1A:

 

Showing top 20/1576 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CHAF1AFBRSL10.814216404
CHAF1AUBE2T0.796894808
CHAF1ATNFAIP8L10.793847505
CHAF1ATIMELESS0.77623612012
CHAF1ASPC240.775581808
CHAF1AMYBL20.77041612012
CHAF1AAURKB0.7686812012
CHAF1ACDCA50.768092707
CHAF1AMTFR20.767687707
CHAF1ANCAPH0.764457909
CHAF1ASAPCD20.76199606
CHAF1ATRIP130.75665212012
CHAF1ARAD510.75430411011
CHAF1ARNASEH2A0.75393412011
CHAF1AUHRF10.753877908
CHAF1ABCL11A0.75134303
CHAF1AKIF18B0.75078611011
CHAF1ATACC30.74479812012
CHAF1AMCM20.74120612012
CHAF1ACDCA20.738673606

For details and further investigation, click here