| Full name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | Alias Symbol: ST3GalV|SIATGM3S | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 8869 | HGNC ID: HGNC:10872 | Ensembl Gene: ENSG00000115525 | OMIM ID: 604402 |
| Drug and gene relationship at DGIdb | |||
Expression of ST3GAL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST3GAL5 | 8869 | 203217_s_at | 0.6806 | 0.3443 | |
| GSE20347 | ST3GAL5 | 8869 | 203217_s_at | 0.6637 | 0.0005 | |
| GSE23400 | ST3GAL5 | 8869 | 203217_s_at | 0.1086 | 0.0967 | |
| GSE26886 | ST3GAL5 | 8869 | 203217_s_at | 0.5712 | 0.0761 | |
| GSE29001 | ST3GAL5 | 8869 | 203217_s_at | 0.4004 | 0.0252 | |
| GSE38129 | ST3GAL5 | 8869 | 203217_s_at | 0.3069 | 0.1652 | |
| GSE45670 | ST3GAL5 | 8869 | 203217_s_at | 0.1816 | 0.6387 | |
| GSE53622 | ST3GAL5 | 8869 | 10097 | 0.6232 | 0.0001 | |
| GSE53624 | ST3GAL5 | 8869 | 10097 | 0.5310 | 0.0020 | |
| GSE63941 | ST3GAL5 | 8869 | 203217_s_at | -3.1669 | 0.0003 | |
| GSE77861 | ST3GAL5 | 8869 | 203217_s_at | 0.1132 | 0.4255 | |
| GSE97050 | ST3GAL5 | 8869 | A_23_P136573 | 0.1348 | 0.5473 | |
| SRP007169 | ST3GAL5 | 8869 | RNAseq | 3.9824 | 0.0000 | |
| SRP064894 | ST3GAL5 | 8869 | RNAseq | 0.4685 | 0.1107 | |
| SRP133303 | ST3GAL5 | 8869 | RNAseq | 0.5369 | 0.0437 | |
| SRP159526 | ST3GAL5 | 8869 | RNAseq | 0.9993 | 0.0210 | |
| SRP193095 | ST3GAL5 | 8869 | RNAseq | 0.7860 | 0.0004 | |
| SRP219564 | ST3GAL5 | 8869 | RNAseq | 0.9589 | 0.0341 | |
| TCGA | ST3GAL5 | 8869 | RNAseq | 0.0737 | 0.5983 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ST3GAL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST3GAL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST3GAL5 | 8869 | 9 | 2 | 19 | |
| GSE20123 | ST3GAL5 | 8869 | 9 | 2 | 19 | |
| GSE43470 | ST3GAL5 | 8869 | 4 | 2 | 37 | |
| GSE46452 | ST3GAL5 | 8869 | 2 | 3 | 54 | |
| GSE47630 | ST3GAL5 | 8869 | 7 | 0 | 33 | |
| GSE54993 | ST3GAL5 | 8869 | 0 | 6 | 64 | |
| GSE54994 | ST3GAL5 | 8869 | 10 | 0 | 43 | |
| GSE60625 | ST3GAL5 | 8869 | 0 | 3 | 8 | |
| GSE74703 | ST3GAL5 | 8869 | 4 | 1 | 31 | |
| GSE74704 | ST3GAL5 | 8869 | 7 | 0 | 13 | |
| TCGA | ST3GAL5 | 8869 | 35 | 4 | 57 |
Total number of gains: 87; Total number of losses: 23; Total Number of normals: 378.
Somatic mutations of ST3GAL5:
Generating mutation plots.
Highly correlated genes for ST3GAL5:
Showing top 20/971 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST3GAL5 | GIMAP1 | 0.766975 | 3 | 0 | 3 |
| ST3GAL5 | TRIM5 | 0.745397 | 3 | 0 | 3 |
| ST3GAL5 | GNGT2 | 0.72873 | 4 | 0 | 3 |
| ST3GAL5 | PRPH2 | 0.722561 | 3 | 0 | 3 |
| ST3GAL5 | FAM167B | 0.718234 | 3 | 0 | 3 |
| ST3GAL5 | PSME1 | 0.717265 | 3 | 0 | 3 |
| ST3GAL5 | TMEM60 | 0.713477 | 3 | 0 | 3 |
| ST3GAL5 | FMNL3 | 0.711214 | 5 | 0 | 5 |
| ST3GAL5 | SUCNR1 | 0.710916 | 4 | 0 | 4 |
| ST3GAL5 | LRRC8C | 0.702781 | 3 | 0 | 3 |
| ST3GAL5 | LMO1 | 0.702131 | 4 | 0 | 3 |
| ST3GAL5 | TMEM98 | 0.696961 | 3 | 0 | 3 |
| ST3GAL5 | CD44 | 0.696203 | 3 | 0 | 3 |
| ST3GAL5 | PRICKLE2 | 0.695764 | 3 | 0 | 3 |
| ST3GAL5 | ITGA1 | 0.695404 | 4 | 0 | 4 |
| ST3GAL5 | CXCL5 | 0.693157 | 5 | 0 | 4 |
| ST3GAL5 | EPHA3 | 0.691221 | 3 | 0 | 3 |
| ST3GAL5 | GCSH | 0.687273 | 3 | 0 | 3 |
| ST3GAL5 | ANK2 | 0.686092 | 3 | 0 | 3 |
| ST3GAL5 | FCGR3A | 0.68498 | 3 | 0 | 3 |
For details and further investigation, click here
