| Full name: proline rich 5 | Alias Symbol: PP610|FLJ20185k|Protor-1 | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 55615 | HGNC ID: HGNC:31682 | Ensembl Gene: ENSG00000186654 | OMIM ID: 609406 |
| Drug and gene relationship at DGIdb | |||
Expression of PRR5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR5 | 55615 | 47069_at | 0.8866 | 0.0559 | |
| GSE20347 | PRR5 | 55615 | 47069_at | 0.6266 | 0.0019 | |
| GSE23400 | PRR5 | 55615 | 47069_at | 0.4172 | 0.0000 | |
| GSE26886 | PRR5 | 55615 | 47069_at | 0.3152 | 0.2490 | |
| GSE29001 | PRR5 | 55615 | 47069_at | 0.5678 | 0.0790 | |
| GSE38129 | PRR5 | 55615 | 47069_at | 0.7471 | 0.0000 | |
| GSE45670 | PRR5 | 55615 | 47069_at | 0.5840 | 0.0239 | |
| GSE53622 | PRR5 | 55615 | 74408 | 0.6347 | 0.0000 | |
| GSE53624 | PRR5 | 55615 | 74408 | 0.8147 | 0.0000 | |
| GSE63941 | PRR5 | 55615 | 47069_at | -0.1901 | 0.7179 | |
| GSE77861 | PRR5 | 55615 | 47069_at | 0.5990 | 0.0026 | |
| GSE97050 | PRR5 | 55615 | A_33_P3215929 | -0.0221 | 0.9699 | |
| SRP007169 | PRR5 | 55615 | RNAseq | 0.6348 | 0.1766 | |
| SRP008496 | PRR5 | 55615 | RNAseq | 0.8847 | 0.0102 | |
| SRP064894 | PRR5 | 55615 | RNAseq | 1.0239 | 0.0032 | |
| SRP133303 | PRR5 | 55615 | RNAseq | 0.4548 | 0.0193 | |
| SRP159526 | PRR5 | 55615 | RNAseq | 0.8403 | 0.0015 | |
| SRP193095 | PRR5 | 55615 | RNAseq | 0.3776 | 0.0032 | |
| SRP219564 | PRR5 | 55615 | RNAseq | 1.2940 | 0.0002 | |
| TCGA | PRR5 | 55615 | RNAseq | 0.2926 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PRR5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR5 | 55615 | 5 | 7 | 18 | |
| GSE20123 | PRR5 | 55615 | 4 | 6 | 20 | |
| GSE43470 | PRR5 | 55615 | 2 | 6 | 35 | |
| GSE46452 | PRR5 | 55615 | 31 | 2 | 26 | |
| GSE47630 | PRR5 | 55615 | 9 | 4 | 27 | |
| GSE54993 | PRR5 | 55615 | 3 | 6 | 61 | |
| GSE54994 | PRR5 | 55615 | 11 | 8 | 34 | |
| GSE60625 | PRR5 | 55615 | 5 | 0 | 6 | |
| GSE74703 | PRR5 | 55615 | 2 | 4 | 30 | |
| GSE74704 | PRR5 | 55615 | 2 | 3 | 15 | |
| TCGA | PRR5 | 55615 | 26 | 15 | 55 |
Total number of gains: 100; Total number of losses: 61; Total Number of normals: 327.
Somatic mutations of PRR5:
Generating mutation plots.
Highly correlated genes for PRR5:
Showing top 20/725 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR5 | C19orf48 | 0.696424 | 3 | 0 | 3 |
| PRR5 | PIGU | 0.695898 | 3 | 0 | 3 |
| PRR5 | BEND3 | 0.690029 | 6 | 0 | 6 |
| PRR5 | CENPM | 0.688845 | 9 | 0 | 9 |
| PRR5 | CDC45 | 0.688625 | 9 | 0 | 8 |
| PRR5 | FLAD1 | 0.68188 | 11 | 0 | 10 |
| PRR5 | NUF2 | 0.67971 | 5 | 0 | 5 |
| PRR5 | BOP1 | 0.679608 | 3 | 0 | 3 |
| PRR5 | CMSS1 | 0.678074 | 5 | 0 | 5 |
| PRR5 | GORAB | 0.677098 | 6 | 0 | 6 |
| PRR5 | MET | 0.675688 | 6 | 0 | 6 |
| PRR5 | BID | 0.67354 | 8 | 0 | 8 |
| PRR5 | CDCA5 | 0.672117 | 6 | 0 | 6 |
| PRR5 | ECE2 | 0.668263 | 7 | 0 | 6 |
| PRR5 | KIF14 | 0.666485 | 8 | 0 | 7 |
| PRR5 | BYSL | 0.665941 | 9 | 0 | 8 |
| PRR5 | DNAJB11 | 0.665838 | 6 | 0 | 6 |
| PRR5 | KIF26B | 0.665381 | 5 | 0 | 5 |
| PRR5 | RUVBL1 | 0.662612 | 9 | 0 | 8 |
| PRR5 | GMNN | 0.662559 | 8 | 0 | 8 |
For details and further investigation, click here
