| Full name: parathyroid hormone 2 receptor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q34 | ||
| Entrez ID: 5746 | HGNC ID: HGNC:9609 | Ensembl Gene: ENSG00000144407 | OMIM ID: 601469 |
| Drug and gene relationship at DGIdb | |||
Expression of PTH2R:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTH2R | 5746 | 206772_at | 1.5448 | 0.3881 | |
| GSE20347 | PTH2R | 5746 | 206772_at | 1.5092 | 0.0007 | |
| GSE23400 | PTH2R | 5746 | 206772_at | 0.4020 | 0.0000 | |
| GSE26886 | PTH2R | 5746 | 206772_at | 1.8600 | 0.0027 | |
| GSE29001 | PTH2R | 5746 | 206772_at | 0.7191 | 0.0875 | |
| GSE38129 | PTH2R | 5746 | 206772_at | 1.6883 | 0.0000 | |
| GSE45670 | PTH2R | 5746 | 206772_at | 1.4819 | 0.0313 | |
| GSE53622 | PTH2R | 5746 | 34776 | 0.1490 | 0.0450 | |
| GSE53624 | PTH2R | 5746 | 34776 | 0.1153 | 0.0749 | |
| GSE63941 | PTH2R | 5746 | 206772_at | 2.0206 | 0.2617 | |
| GSE77861 | PTH2R | 5746 | 206772_at | 0.5582 | 0.0765 | |
| SRP007169 | PTH2R | 5746 | RNAseq | 6.3065 | 0.0000 | |
| SRP133303 | PTH2R | 5746 | RNAseq | 3.3941 | 0.0000 | |
| SRP159526 | PTH2R | 5746 | RNAseq | 4.8625 | 0.0000 | |
| TCGA | PTH2R | 5746 | RNAseq | 3.4096 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by PTH2R expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTH2R:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTH2R | 5746 | 3 | 10 | 17 | |
| GSE20123 | PTH2R | 5746 | 3 | 10 | 17 | |
| GSE43470 | PTH2R | 5746 | 2 | 4 | 37 | |
| GSE46452 | PTH2R | 5746 | 0 | 5 | 54 | |
| GSE47630 | PTH2R | 5746 | 4 | 5 | 31 | |
| GSE54993 | PTH2R | 5746 | 0 | 3 | 67 | |
| GSE54994 | PTH2R | 5746 | 9 | 9 | 35 | |
| GSE60625 | PTH2R | 5746 | 0 | 3 | 8 | |
| GSE74703 | PTH2R | 5746 | 2 | 3 | 31 | |
| GSE74704 | PTH2R | 5746 | 2 | 5 | 13 | |
| TCGA | PTH2R | 5746 | 12 | 23 | 61 |
Total number of gains: 37; Total number of losses: 80; Total Number of normals: 371.
Somatic mutations of PTH2R:
Generating mutation plots.
Highly correlated genes for PTH2R:
Showing top 20/261 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTH2R | MTCH1 | 0.712353 | 4 | 0 | 4 |
| PTH2R | KIAA1324L | 0.708611 | 3 | 0 | 3 |
| PTH2R | RHBDD2 | 0.696961 | 3 | 0 | 3 |
| PTH2R | UBB | 0.684074 | 3 | 0 | 3 |
| PTH2R | RAI1 | 0.682671 | 3 | 0 | 3 |
| PTH2R | TAF6 | 0.666323 | 4 | 0 | 3 |
| PTH2R | CHST14 | 0.660064 | 3 | 0 | 3 |
| PTH2R | SDCCAG8 | 0.650091 | 4 | 0 | 3 |
| PTH2R | UBE2I | 0.644721 | 3 | 0 | 3 |
| PTH2R | CYP2S1 | 0.644199 | 3 | 0 | 3 |
| PTH2R | CEP290 | 0.639428 | 5 | 0 | 4 |
| PTH2R | SEPHS2 | 0.638078 | 4 | 0 | 3 |
| PTH2R | PPP1R35 | 0.62966 | 3 | 0 | 3 |
| PTH2R | TM2D1 | 0.628244 | 4 | 0 | 3 |
| PTH2R | TSC22D1 | 0.628158 | 3 | 0 | 3 |
| PTH2R | SP4 | 0.625915 | 3 | 0 | 3 |
| PTH2R | XPO1 | 0.621606 | 4 | 0 | 3 |
| PTH2R | USP42 | 0.620533 | 4 | 0 | 3 |
| PTH2R | KIAA1549 | 0.619618 | 3 | 0 | 3 |
| PTH2R | ZNF3 | 0.617909 | 4 | 0 | 3 |
For details and further investigation, click here
