| Full name: protein tyrosine phosphatase receptor type G | Alias Symbol: RPTPG | ||
| Type: protein-coding gene | Cytoband: 3p14.2 | ||
| Entrez ID: 5793 | HGNC ID: HGNC:9671 | Ensembl Gene: ENSG00000144724 | OMIM ID: 176886 |
| Drug and gene relationship at DGIdb | |||
Expression of PTPRG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTPRG | 5793 | 227126_at | 0.0901 | 0.9367 | |
| GSE20347 | PTPRG | 5793 | 204944_at | 0.8218 | 0.0015 | |
| GSE23400 | PTPRG | 5793 | 204944_at | 0.5597 | 0.0000 | |
| GSE26886 | PTPRG | 5793 | 244574_at | -0.2144 | 0.0391 | |
| GSE29001 | PTPRG | 5793 | 204944_at | 0.7734 | 0.0179 | |
| GSE38129 | PTPRG | 5793 | 204944_at | 0.8616 | 0.0007 | |
| GSE45670 | PTPRG | 5793 | 227126_at | -0.4378 | 0.1921 | |
| GSE53622 | PTPRG | 5793 | 22730 | 0.2292 | 0.0009 | |
| GSE53624 | PTPRG | 5793 | 22730 | -0.7813 | 0.0000 | |
| GSE63941 | PTPRG | 5793 | 204944_at | -3.4623 | 0.0055 | |
| GSE77861 | PTPRG | 5793 | 244574_at | -0.1559 | 0.0596 | |
| GSE97050 | PTPRG | 5793 | A_33_P3245278 | -0.1539 | 0.6284 | |
| SRP007169 | PTPRG | 5793 | RNAseq | 2.2056 | 0.0000 | |
| SRP008496 | PTPRG | 5793 | RNAseq | 2.6749 | 0.0000 | |
| SRP064894 | PTPRG | 5793 | RNAseq | 0.8495 | 0.0170 | |
| SRP133303 | PTPRG | 5793 | RNAseq | 0.6492 | 0.0211 | |
| SRP159526 | PTPRG | 5793 | RNAseq | 0.4293 | 0.2135 | |
| SRP193095 | PTPRG | 5793 | RNAseq | 0.9484 | 0.0000 | |
| SRP219564 | PTPRG | 5793 | RNAseq | -0.0785 | 0.8246 | |
| TCGA | PTPRG | 5793 | RNAseq | -0.1844 | 0.0708 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by PTPRG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTPRG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTPRG | 5793 | 0 | 18 | 12 | |
| GSE20123 | PTPRG | 5793 | 0 | 18 | 12 | |
| GSE43470 | PTPRG | 5793 | 0 | 19 | 24 | |
| GSE46452 | PTPRG | 5793 | 2 | 17 | 40 | |
| GSE47630 | PTPRG | 5793 | 1 | 24 | 15 | |
| GSE54993 | PTPRG | 5793 | 5 | 2 | 63 | |
| GSE54994 | PTPRG | 5793 | 1 | 32 | 20 | |
| GSE60625 | PTPRG | 5793 | 3 | 1 | 7 | |
| GSE74703 | PTPRG | 5793 | 0 | 16 | 20 | |
| GSE74704 | PTPRG | 5793 | 0 | 12 | 8 | |
| TCGA | PTPRG | 5793 | 0 | 79 | 17 |
Total number of gains: 12; Total number of losses: 238; Total Number of normals: 238.
Somatic mutations of PTPRG:
Generating mutation plots.
Highly correlated genes for PTPRG:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTPRG | CRYZ | 0.803919 | 3 | 0 | 3 |
| PTPRG | AGL | 0.781036 | 3 | 0 | 3 |
| PTPRG | S1PR1 | 0.752043 | 3 | 0 | 3 |
| PTPRG | TM4SF18 | 0.751235 | 4 | 0 | 4 |
| PTPRG | RAD50 | 0.746051 | 3 | 0 | 3 |
| PTPRG | DIXDC1 | 0.737074 | 3 | 0 | 3 |
| PTPRG | EPG5 | 0.725422 | 3 | 0 | 3 |
| PTPRG | RAB11FIP2 | 0.725247 | 3 | 0 | 3 |
| PTPRG | VDAC3 | 0.720327 | 3 | 0 | 3 |
| PTPRG | STAU1 | 0.709834 | 4 | 0 | 4 |
| PTPRG | ZCCHC24 | 0.709519 | 3 | 0 | 3 |
| PTPRG | COG6 | 0.707157 | 3 | 0 | 3 |
| PTPRG | CYYR1 | 0.705374 | 3 | 0 | 3 |
| PTPRG | MCFD2 | 0.700591 | 3 | 0 | 3 |
| PTPRG | TMX3 | 0.699761 | 4 | 0 | 3 |
| PTPRG | C11orf96 | 0.699392 | 3 | 0 | 3 |
| PTPRG | EIF4G2 | 0.696806 | 3 | 0 | 3 |
| PTPRG | LYSMD3 | 0.695111 | 4 | 0 | 4 |
| PTPRG | AK3 | 0.69489 | 3 | 0 | 3 |
| PTPRG | UBE2Q2 | 0.693618 | 3 | 0 | 3 |
For details and further investigation, click here
