| Full name: adipogenesis regulatory factor | Alias Symbol: APM2|AFRO | ||
| Type: protein-coding gene | Cytoband: 10q23.2 | ||
| Entrez ID: 10974 | HGNC ID: HGNC:24043 | Ensembl Gene: ENSG00000148671 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADIRF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADIRF | 10974 | 203571_s_at | -0.7105 | 0.4893 | |
| GSE20347 | ADIRF | 10974 | 203571_s_at | -2.0389 | 0.0000 | |
| GSE23400 | ADIRF | 10974 | 203571_s_at | -2.1804 | 0.0000 | |
| GSE26886 | ADIRF | 10974 | 203571_s_at | -0.5204 | 0.1217 | |
| GSE29001 | ADIRF | 10974 | 203571_s_at | -2.2854 | 0.0007 | |
| GSE38129 | ADIRF | 10974 | 203571_s_at | -2.2612 | 0.0000 | |
| GSE45670 | ADIRF | 10974 | 203571_s_at | -1.1089 | 0.0026 | |
| GSE63941 | ADIRF | 10974 | 203571_s_at | 1.5679 | 0.4251 | |
| GSE77861 | ADIRF | 10974 | 203571_s_at | -1.4195 | 0.0148 | |
| SRP007169 | ADIRF | 10974 | RNAseq | -3.6616 | 0.0003 | |
| SRP008496 | ADIRF | 10974 | RNAseq | -3.6118 | 0.0001 | |
| SRP064894 | ADIRF | 10974 | RNAseq | -2.6633 | 0.0000 | |
| SRP133303 | ADIRF | 10974 | RNAseq | -2.1373 | 0.0000 | |
| SRP159526 | ADIRF | 10974 | RNAseq | -2.5140 | 0.0000 | |
| SRP193095 | ADIRF | 10974 | RNAseq | -2.7458 | 0.0000 | |
| SRP219564 | ADIRF | 10974 | RNAseq | -2.7162 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 13.
Copy number change of ADIRF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADIRF | 10974 | 1 | 7 | 22 | |
| GSE20123 | ADIRF | 10974 | 1 | 6 | 23 | |
| GSE43470 | ADIRF | 10974 | 0 | 7 | 36 | |
| GSE46452 | ADIRF | 10974 | 0 | 11 | 48 | |
| GSE47630 | ADIRF | 10974 | 2 | 14 | 24 | |
| GSE54993 | ADIRF | 10974 | 7 | 0 | 63 | |
| GSE54994 | ADIRF | 10974 | 1 | 12 | 40 | |
| GSE60625 | ADIRF | 10974 | 0 | 0 | 11 | |
| GSE74703 | ADIRF | 10974 | 0 | 5 | 31 | |
| GSE74704 | ADIRF | 10974 | 0 | 4 | 16 | |
| TCGA | ADIRF | 10974 | 7 | 27 | 62 |
Total number of gains: 19; Total number of losses: 93; Total Number of normals: 376.
Somatic mutations of ADIRF:
Generating mutation plots.
Highly correlated genes for ADIRF:
Showing top 20/828 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADIRF | HPGD | 0.768898 | 8 | 0 | 8 |
| ADIRF | SLURP1 | 0.754988 | 6 | 0 | 6 |
| ADIRF | ARHGAP10 | 0.754412 | 7 | 0 | 7 |
| ADIRF | PWWP2B | 0.740218 | 4 | 0 | 4 |
| ADIRF | C5orf66-AS1 | 0.7396 | 4 | 0 | 4 |
| ADIRF | RNF141 | 0.732638 | 6 | 0 | 6 |
| ADIRF | ABHD5 | 0.730514 | 7 | 0 | 6 |
| ADIRF | HEBP2 | 0.726599 | 8 | 0 | 7 |
| ADIRF | HOPX | 0.726373 | 6 | 0 | 6 |
| ADIRF | CLIC3 | 0.722385 | 7 | 0 | 6 |
| ADIRF | TMOD3 | 0.719307 | 6 | 0 | 6 |
| ADIRF | CXCR2 | 0.717102 | 7 | 0 | 6 |
| ADIRF | TAX1BP1 | 0.716248 | 7 | 0 | 7 |
| ADIRF | RAB5B | 0.714419 | 8 | 0 | 7 |
| ADIRF | CRYL1 | 0.713589 | 7 | 0 | 6 |
| ADIRF | GYS2 | 0.711457 | 8 | 0 | 7 |
| ADIRF | EHD3 | 0.711345 | 7 | 0 | 7 |
| ADIRF | SPINK5 | 0.70985 | 7 | 0 | 6 |
| ADIRF | SASH1 | 0.706901 | 8 | 0 | 7 |
| ADIRF | ZDHHC13 | 0.706699 | 6 | 0 | 6 |
For details and further investigation, click here
