| Full name: metallothionein 1F | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 4494 | HGNC ID: HGNC:7398 | Ensembl Gene: ENSG00000198417 | OMIM ID: 156352 |
| Drug and gene relationship at DGIdb | |||
Expression of MT1F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MT1F | 4494 | 217165_x_at | -0.0193 | 0.9874 | |
| GSE20347 | MT1F | 4494 | 217165_x_at | 0.1584 | 0.5506 | |
| GSE23400 | MT1F | 4494 | 217165_x_at | -0.2177 | 0.1392 | |
| GSE26886 | MT1F | 4494 | 217165_x_at | 0.2239 | 0.7170 | |
| GSE29001 | MT1F | 4494 | 217165_x_at | -0.1512 | 0.6172 | |
| GSE38129 | MT1F | 4494 | 217165_x_at | -0.1022 | 0.7639 | |
| GSE45670 | MT1F | 4494 | 217165_x_at | -0.6859 | 0.0343 | |
| GSE53622 | MT1F | 4494 | 136628 | 0.3063 | 0.0446 | |
| GSE53624 | MT1F | 4494 | 136628 | 0.3690 | 0.0012 | |
| GSE63941 | MT1F | 4494 | 217165_x_at | -1.5479 | 0.1692 | |
| GSE77861 | MT1F | 4494 | 217165_x_at | -0.5662 | 0.2581 | |
| GSE97050 | MT1F | 4494 | A_23_P15174 | 0.0752 | 0.8955 | |
| SRP064894 | MT1F | 4494 | RNAseq | 0.0036 | 0.9930 | |
| SRP133303 | MT1F | 4494 | RNAseq | 0.4651 | 0.3039 | |
| SRP159526 | MT1F | 4494 | RNAseq | 1.3362 | 0.0428 | |
| SRP193095 | MT1F | 4494 | RNAseq | -0.3727 | 0.3006 | |
| SRP219564 | MT1F | 4494 | RNAseq | 1.9409 | 0.0000 | |
| TCGA | MT1F | 4494 | RNAseq | -0.7976 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MT1F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MT1F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MT1F | 4494 | 5 | 0 | 25 | |
| GSE20123 | MT1F | 4494 | 5 | 1 | 24 | |
| GSE43470 | MT1F | 4494 | 2 | 7 | 34 | |
| GSE46452 | MT1F | 4494 | 38 | 1 | 20 | |
| GSE47630 | MT1F | 4494 | 10 | 8 | 22 | |
| GSE54993 | MT1F | 4494 | 2 | 4 | 64 | |
| GSE54994 | MT1F | 4494 | 7 | 10 | 36 | |
| GSE60625 | MT1F | 4494 | 4 | 0 | 7 | |
| GSE74703 | MT1F | 4494 | 2 | 4 | 30 | |
| GSE74704 | MT1F | 4494 | 4 | 0 | 16 | |
| TCGA | MT1F | 4494 | 25 | 13 | 58 |
Total number of gains: 104; Total number of losses: 48; Total Number of normals: 336.
Somatic mutations of MT1F:
Generating mutation plots.
Highly correlated genes for MT1F:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MT1F | MT1G | 0.86156 | 11 | 0 | 10 |
| MT1F | MT1HL1 | 0.861269 | 11 | 0 | 9 |
| MT1F | MT1X | 0.856898 | 11 | 0 | 10 |
| MT1F | MT1H | 0.833236 | 12 | 0 | 10 |
| MT1F | MT2A | 0.814396 | 12 | 0 | 11 |
| MT1F | SNCA | 0.73595 | 3 | 0 | 3 |
| MT1F | LEPROT | 0.731699 | 3 | 0 | 3 |
| MT1F | MT1E | 0.699544 | 12 | 0 | 10 |
| MT1F | RABGGTB | 0.665853 | 3 | 0 | 3 |
| MT1F | SPATA3-AS1 | 0.60699 | 3 | 0 | 3 |
| MT1F | SOCS3 | 0.59821 | 4 | 0 | 3 |
| MT1F | FEZ2 | 0.597792 | 4 | 0 | 4 |
| MT1F | NES | 0.597065 | 3 | 0 | 3 |
| MT1F | KIFC3 | 0.594873 | 3 | 0 | 3 |
| MT1F | GNG12 | 0.587342 | 4 | 0 | 3 |
| MT1F | GPX8 | 0.58095 | 3 | 0 | 3 |
| MT1F | PAPSS1 | 0.580733 | 3 | 0 | 3 |
| MT1F | TAGLN3 | 0.576934 | 3 | 0 | 3 |
| MT1F | MT4 | 0.569172 | 4 | 0 | 4 |
| MT1F | TAC1 | 0.565768 | 3 | 0 | 3 |
For details and further investigation, click here
