RAP1GAP2

 

Full name: RAP1 GTPase activating protein 2 Alias Symbol: KIAA1039
Type: protein-coding gene Cytoband: 17p13.3
Entrez ID: 23108 HGNC ID: HGNC:29176 Ensembl Gene: ENSG00000132359 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of RAP1GAP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RAP1GAP2 23108 213280_at 0.2125 0.7288
GSE20347 RAP1GAP2 23108 213280_at 0.3976 0.0465
GSE23400 RAP1GAP2 23108 213280_at 0.3039 0.0006
GSE26886 RAP1GAP2 23108 213280_at 1.1787 0.0000
GSE29001 RAP1GAP2 23108 213280_at 0.5573 0.0982
GSE38129 RAP1GAP2 23108 213280_at 0.4408 0.0237
GSE45670 RAP1GAP2 23108 213280_at 0.5447 0.0536
GSE53622 RAP1GAP2 23108 65585 0.4010 0.0006
GSE53624 RAP1GAP2 23108 65585 0.4755 0.0000
GSE63941 RAP1GAP2 23108 213280_at 2.5751 0.0084
GSE77861 RAP1GAP2 23108 213280_at 0.8125 0.0575
GSE97050 RAP1GAP2 23108 A_33_P3333146 0.5381 0.1604
SRP007169 RAP1GAP2 23108 RNAseq 0.7100 0.4144
SRP064894 RAP1GAP2 23108 RNAseq 0.0412 0.9071
SRP133303 RAP1GAP2 23108 RNAseq -0.0586 0.7550
SRP159526 RAP1GAP2 23108 RNAseq 1.1624 0.0001
SRP193095 RAP1GAP2 23108 RNAseq 0.5432 0.0423
SRP219564 RAP1GAP2 23108 RNAseq 0.8311 0.1904
TCGA RAP1GAP2 23108 RNAseq -0.5583 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by RAP1GAP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RAP1GAP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RAP1GAP2 23108 5 2 23
GSE20123 RAP1GAP2 23108 5 3 22
GSE43470 RAP1GAP2 23108 1 6 36
GSE46452 RAP1GAP2 23108 34 1 24
GSE47630 RAP1GAP2 23108 7 1 32
GSE54993 RAP1GAP2 23108 4 3 63
GSE54994 RAP1GAP2 23108 5 9 39
GSE60625 RAP1GAP2 23108 4 0 7
GSE74703 RAP1GAP2 23108 1 3 32
GSE74704 RAP1GAP2 23108 3 1 16
TCGA RAP1GAP2 23108 16 21 59

Total number of gains: 85; Total number of losses: 50; Total Number of normals: 353.  

 

Somatic mutations of RAP1GAP2:

 

Generating mutation plots.

 

Highly correlated genes for RAP1GAP2:

 

Showing top 20/423 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RAP1GAP2C2orf690.702763404
RAP1GAP2FREM20.702131303
RAP1GAP2FBXO20.700812303
RAP1GAP2PPP1R350.665301403
RAP1GAP2GCLC0.661395303
RAP1GAP2PASK0.647965303
RAP1GAP2HTRA10.646588303
RAP1GAP2SHISA20.640424303
RAP1GAP2MYO190.636019705
RAP1GAP2COA60.635248403
RAP1GAP2CD2760.631579404
RAP1GAP2CEP780.623652505
RAP1GAP2SEMA4F0.621301504
RAP1GAP2TSEN150.619704303
RAP1GAP2EFNA10.618585504
RAP1GAP2GTF2IRD20.617096403
RAP1GAP2TSPAN130.613353403
RAP1GAP2ZBTB240.612545303
RAP1GAP2UBE2T0.609607605
RAP1GAP2ALS20.609424403

For details and further investigation, click here