| Full name: RNA exonuclease 2 | Alias Symbol: DKFZP566E144|SFN|CGI-114 | ||
| Type: protein-coding gene | Cytoband: 11q23.2 | ||
| Entrez ID: 25996 | HGNC ID: HGNC:17851 | Ensembl Gene: ENSG00000076043 | OMIM ID: 607149 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of REXO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | REXO2 | 25996 | 218194_at | -0.4055 | 0.1316 | |
| GSE20347 | REXO2 | 25996 | 218194_at | -0.6225 | 0.0001 | |
| GSE23400 | REXO2 | 25996 | 218194_at | -0.5524 | 0.0000 | |
| GSE26886 | REXO2 | 25996 | 218194_at | -0.8615 | 0.0007 | |
| GSE29001 | REXO2 | 25996 | 218194_at | -0.6945 | 0.0207 | |
| GSE38129 | REXO2 | 25996 | 218194_at | -0.6086 | 0.0000 | |
| GSE45670 | REXO2 | 25996 | 218194_at | -0.2751 | 0.1494 | |
| GSE53622 | REXO2 | 25996 | 52363 | -0.8417 | 0.0000 | |
| GSE53624 | REXO2 | 25996 | 52363 | -0.7639 | 0.0000 | |
| GSE63941 | REXO2 | 25996 | 218194_at | -1.4582 | 0.0073 | |
| GSE77861 | REXO2 | 25996 | 218194_at | -0.4809 | 0.0632 | |
| GSE97050 | REXO2 | 25996 | A_23_P150365 | -0.3574 | 0.2767 | |
| SRP007169 | REXO2 | 25996 | RNAseq | -2.5107 | 0.0000 | |
| SRP008496 | REXO2 | 25996 | RNAseq | -1.7814 | 0.0000 | |
| SRP064894 | REXO2 | 25996 | RNAseq | -0.7547 | 0.0000 | |
| SRP133303 | REXO2 | 25996 | RNAseq | -0.7083 | 0.0003 | |
| SRP159526 | REXO2 | 25996 | RNAseq | -0.9257 | 0.0082 | |
| SRP193095 | REXO2 | 25996 | RNAseq | -1.2211 | 0.0000 | |
| SRP219564 | REXO2 | 25996 | RNAseq | -0.8952 | 0.0175 | |
| TCGA | REXO2 | 25996 | RNAseq | -0.1120 | 0.0737 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by REXO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of REXO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | REXO2 | 25996 | 0 | 13 | 17 | |
| GSE20123 | REXO2 | 25996 | 0 | 13 | 17 | |
| GSE43470 | REXO2 | 25996 | 2 | 7 | 34 | |
| GSE46452 | REXO2 | 25996 | 3 | 26 | 30 | |
| GSE47630 | REXO2 | 25996 | 2 | 19 | 19 | |
| GSE54993 | REXO2 | 25996 | 10 | 0 | 60 | |
| GSE54994 | REXO2 | 25996 | 5 | 19 | 29 | |
| GSE60625 | REXO2 | 25996 | 0 | 3 | 8 | |
| GSE74703 | REXO2 | 25996 | 1 | 5 | 30 | |
| GSE74704 | REXO2 | 25996 | 0 | 9 | 11 | |
| TCGA | REXO2 | 25996 | 6 | 49 | 41 |
Total number of gains: 29; Total number of losses: 163; Total Number of normals: 296.
Somatic mutations of REXO2:
Generating mutation plots.
Highly correlated genes for REXO2:
Showing top 20/1228 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| REXO2 | FIBIN | 0.740338 | 3 | 0 | 3 |
| REXO2 | KCTD6 | 0.725742 | 6 | 0 | 6 |
| REXO2 | NACA2 | 0.722218 | 3 | 0 | 3 |
| REXO2 | GBA2 | 0.713853 | 3 | 0 | 3 |
| REXO2 | TNFRSF19 | 0.702257 | 3 | 0 | 3 |
| REXO2 | CA13 | 0.700017 | 3 | 0 | 3 |
| REXO2 | CYSRT1 | 0.699793 | 6 | 0 | 6 |
| REXO2 | RNF185 | 0.696004 | 4 | 0 | 4 |
| REXO2 | DBNL | 0.692293 | 3 | 0 | 3 |
| REXO2 | GPR108 | 0.69149 | 3 | 0 | 3 |
| REXO2 | SDHD | 0.691095 | 12 | 0 | 11 |
| REXO2 | UBE4A | 0.689446 | 10 | 0 | 9 |
| REXO2 | CASC3 | 0.686298 | 3 | 0 | 3 |
| REXO2 | ESYT2 | 0.681829 | 5 | 0 | 4 |
| REXO2 | THOC7 | 0.681708 | 11 | 0 | 9 |
| REXO2 | RAB5A | 0.680558 | 12 | 0 | 12 |
| REXO2 | CPPED1 | 0.680555 | 11 | 0 | 10 |
| REXO2 | HIGD1A | 0.680197 | 13 | 0 | 11 |
| REXO2 | ARHGEF6 | 0.679897 | 3 | 0 | 3 |
| REXO2 | GPBP1 | 0.678144 | 3 | 0 | 3 |
For details and further investigation, click here
