| Full name: ubiquitin conjugating enzyme E2 G2 | Alias Symbol: UBC7 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 7327 | HGNC ID: HGNC:12483 | Ensembl Gene: ENSG00000184787 | OMIM ID: 603124 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2G2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2G2 | 7327 | 209042_s_at | -0.3158 | 0.3552 | |
| GSE20347 | UBE2G2 | 7327 | 209042_s_at | 0.0921 | 0.5047 | |
| GSE23400 | UBE2G2 | 7327 | 209042_s_at | -0.0402 | 0.6360 | |
| GSE26886 | UBE2G2 | 7327 | 209042_s_at | -0.4534 | 0.0437 | |
| GSE29001 | UBE2G2 | 7327 | 209042_s_at | 0.1621 | 0.5862 | |
| GSE38129 | UBE2G2 | 7327 | 209042_s_at | -0.0865 | 0.5009 | |
| GSE45670 | UBE2G2 | 7327 | 209042_s_at | -0.0752 | 0.6787 | |
| GSE53622 | UBE2G2 | 7327 | 3468 | -0.2727 | 0.0000 | |
| GSE53624 | UBE2G2 | 7327 | 3468 | -0.0827 | 0.1280 | |
| GSE63941 | UBE2G2 | 7327 | 209042_s_at | -1.0428 | 0.0375 | |
| GSE77861 | UBE2G2 | 7327 | 1557053_s_at | -0.0428 | 0.6550 | |
| GSE97050 | UBE2G2 | 7327 | A_24_P357037 | -0.2594 | 0.3775 | |
| SRP007169 | UBE2G2 | 7327 | RNAseq | 0.0173 | 0.9678 | |
| SRP008496 | UBE2G2 | 7327 | RNAseq | 0.3352 | 0.2509 | |
| SRP064894 | UBE2G2 | 7327 | RNAseq | 0.2277 | 0.1487 | |
| SRP133303 | UBE2G2 | 7327 | RNAseq | -0.1748 | 0.2674 | |
| SRP159526 | UBE2G2 | 7327 | RNAseq | -0.0491 | 0.7261 | |
| SRP193095 | UBE2G2 | 7327 | RNAseq | 0.0320 | 0.6987 | |
| SRP219564 | UBE2G2 | 7327 | RNAseq | -0.0274 | 0.9438 | |
| TCGA | UBE2G2 | 7327 | RNAseq | -0.1540 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UBE2G2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2G2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2G2 | 7327 | 2 | 9 | 19 | |
| GSE20123 | UBE2G2 | 7327 | 2 | 9 | 19 | |
| GSE43470 | UBE2G2 | 7327 | 0 | 13 | 30 | |
| GSE46452 | UBE2G2 | 7327 | 1 | 21 | 37 | |
| GSE47630 | UBE2G2 | 7327 | 6 | 17 | 17 | |
| GSE54993 | UBE2G2 | 7327 | 8 | 1 | 61 | |
| GSE54994 | UBE2G2 | 7327 | 4 | 8 | 41 | |
| GSE60625 | UBE2G2 | 7327 | 0 | 0 | 11 | |
| GSE74703 | UBE2G2 | 7327 | 0 | 10 | 26 | |
| GSE74704 | UBE2G2 | 7327 | 1 | 5 | 14 | |
| TCGA | UBE2G2 | 7327 | 9 | 38 | 49 |
Total number of gains: 33; Total number of losses: 131; Total Number of normals: 324.
Somatic mutations of UBE2G2:
Generating mutation plots.
Highly correlated genes for UBE2G2:
Showing top 20/287 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2G2 | RHBDD1 | 0.783824 | 3 | 0 | 3 |
| UBE2G2 | DCTN2 | 0.752772 | 3 | 0 | 3 |
| UBE2G2 | PINK1 | 0.752443 | 4 | 0 | 4 |
| UBE2G2 | IBTK | 0.742676 | 3 | 0 | 3 |
| UBE2G2 | NDUFB8 | 0.739314 | 3 | 0 | 3 |
| UBE2G2 | PNPLA8 | 0.730852 | 3 | 0 | 3 |
| UBE2G2 | PDCD7 | 0.726756 | 4 | 0 | 3 |
| UBE2G2 | ANKRD13C | 0.723162 | 3 | 0 | 3 |
| UBE2G2 | PPM1L | 0.719251 | 3 | 0 | 3 |
| UBE2G2 | DUSP22 | 0.717173 | 3 | 0 | 3 |
| UBE2G2 | NCOA1 | 0.711069 | 3 | 0 | 3 |
| UBE2G2 | CNOT4 | 0.708357 | 4 | 0 | 3 |
| UBE2G2 | PPCS | 0.707533 | 3 | 0 | 3 |
| UBE2G2 | SLC37A3 | 0.700939 | 3 | 0 | 3 |
| UBE2G2 | ST6GALNAC6 | 0.699807 | 3 | 0 | 3 |
| UBE2G2 | LGALSL | 0.69977 | 3 | 0 | 3 |
| UBE2G2 | RGS14 | 0.697268 | 3 | 0 | 3 |
| UBE2G2 | ZNF800 | 0.697164 | 3 | 0 | 3 |
| UBE2G2 | HOOK3 | 0.695321 | 3 | 0 | 3 |
| UBE2G2 | GLUD1 | 0.691067 | 3 | 0 | 3 |
For details and further investigation, click here
