| Full name: regulator of microtubule dynamics 3 | Alias Symbol: FLJ10579|PTPIP51|RMD3 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 55177 | HGNC ID: HGNC:25550 | Ensembl Gene: ENSG00000137824 | OMIM ID: 611873 |
| Drug and gene relationship at DGIdb | |||
Expression of RMDN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RMDN3 | 55177 | 218126_at | -0.0416 | 0.9135 | |
| GSE20347 | RMDN3 | 55177 | 218126_at | 0.0371 | 0.6967 | |
| GSE23400 | RMDN3 | 55177 | 218126_at | -0.0006 | 0.9905 | |
| GSE26886 | RMDN3 | 55177 | 218126_at | 0.0683 | 0.7184 | |
| GSE29001 | RMDN3 | 55177 | 218126_at | 0.0983 | 0.7277 | |
| GSE38129 | RMDN3 | 55177 | 218126_at | 0.0322 | 0.6774 | |
| GSE45670 | RMDN3 | 55177 | 218126_at | -0.0786 | 0.4760 | |
| GSE53622 | RMDN3 | 55177 | 91973 | -0.1231 | 0.0464 | |
| GSE53624 | RMDN3 | 55177 | 91973 | 0.0182 | 0.7444 | |
| GSE63941 | RMDN3 | 55177 | 218126_at | -0.7341 | 0.0867 | |
| GSE77861 | RMDN3 | 55177 | 218126_at | -0.1072 | 0.5969 | |
| SRP007169 | RMDN3 | 55177 | RNAseq | -0.0989 | 0.8353 | |
| SRP008496 | RMDN3 | 55177 | RNAseq | -0.4231 | 0.1450 | |
| SRP064894 | RMDN3 | 55177 | RNAseq | -0.0924 | 0.4901 | |
| SRP133303 | RMDN3 | 55177 | RNAseq | 0.1543 | 0.1617 | |
| SRP159526 | RMDN3 | 55177 | RNAseq | -0.0682 | 0.8139 | |
| SRP193095 | RMDN3 | 55177 | RNAseq | -0.0467 | 0.6425 | |
| SRP219564 | RMDN3 | 55177 | RNAseq | -0.1813 | 0.5166 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RMDN3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of RMDN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RMDN3 | 55177 | 3 | 6 | 21 | |
| GSE20123 | RMDN3 | 55177 | 3 | 6 | 21 | |
| GSE43470 | RMDN3 | 55177 | 4 | 6 | 33 | |
| GSE46452 | RMDN3 | 55177 | 3 | 7 | 49 | |
| GSE47630 | RMDN3 | 55177 | 8 | 11 | 21 | |
| GSE54993 | RMDN3 | 55177 | 4 | 6 | 60 | |
| GSE54994 | RMDN3 | 55177 | 5 | 7 | 41 | |
| GSE60625 | RMDN3 | 55177 | 4 | 0 | 7 | |
| GSE74703 | RMDN3 | 55177 | 4 | 5 | 27 | |
| GSE74704 | RMDN3 | 55177 | 2 | 4 | 14 | |
| TCGA | RMDN3 | 55177 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 76; Total Number of normals: 361.
Somatic mutations of RMDN3:
Generating mutation plots.
Highly correlated genes for RMDN3:
Showing top 20/30 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RMDN3 | HERC2 | 0.684646 | 3 | 0 | 3 |
| RMDN3 | LINC01003 | 0.661188 | 3 | 0 | 3 |
| RMDN3 | DTWD1 | 0.62685 | 4 | 0 | 3 |
| RMDN3 | GPATCH11 | 0.622603 | 3 | 0 | 3 |
| RMDN3 | PNN | 0.602957 | 6 | 0 | 4 |
| RMDN3 | ERI2 | 0.591969 | 4 | 0 | 3 |
| RMDN3 | ICE2 | 0.572204 | 5 | 0 | 4 |
| RMDN3 | RNF111 | 0.56852 | 5 | 0 | 3 |
| RMDN3 | C21orf91 | 0.563966 | 3 | 0 | 3 |
| RMDN3 | C10orf88 | 0.562668 | 3 | 0 | 3 |
| RMDN3 | DNAJC17 | 0.560615 | 4 | 0 | 3 |
| RMDN3 | IREB2 | 0.556957 | 4 | 0 | 4 |
| RMDN3 | UROS | 0.555307 | 4 | 0 | 3 |
| RMDN3 | COPS3 | 0.547471 | 3 | 0 | 3 |
| RMDN3 | TUBGCP4 | 0.546745 | 5 | 0 | 3 |
| RMDN3 | MAPK10 | 0.543331 | 4 | 0 | 4 |
| RMDN3 | STOML1 | 0.537649 | 5 | 0 | 3 |
| RMDN3 | MCM9 | 0.53646 | 4 | 0 | 3 |
| RMDN3 | CASP3 | 0.52696 | 4 | 0 | 3 |
| RMDN3 | SLC30A5 | 0.526552 | 4 | 0 | 3 |
For details and further investigation, click here
