| Full name: sterile alpha motif domain containing 11 | Alias Symbol: MGC45873 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 148398 | HGNC ID: HGNC:28706 | Ensembl Gene: ENSG00000187634 | OMIM ID: 616765 |
| Drug and gene relationship at DGIdb | |||
Expression of SAMD11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAMD11 | 148398 | 1560477_a_at | 0.0599 | 0.8995 | |
| GSE26886 | SAMD11 | 148398 | 1560477_a_at | -0.0450 | 0.7095 | |
| GSE45670 | SAMD11 | 148398 | 1560477_a_at | 0.1578 | 0.2280 | |
| GSE53622 | SAMD11 | 148398 | 127596 | -0.0419 | 0.4536 | |
| GSE53624 | SAMD11 | 148398 | 127596 | 0.0493 | 0.2727 | |
| GSE63941 | SAMD11 | 148398 | 1560477_a_at | -1.0006 | 0.0121 | |
| GSE77861 | SAMD11 | 148398 | 1560477_a_at | 0.0730 | 0.4471 | |
| GSE97050 | SAMD11 | 148398 | A_33_P3818959 | -0.0047 | 0.9875 | |
| SRP064894 | SAMD11 | 148398 | RNAseq | 1.5086 | 0.0049 | |
| SRP133303 | SAMD11 | 148398 | RNAseq | -0.2666 | 0.5881 | |
| SRP159526 | SAMD11 | 148398 | RNAseq | 1.2965 | 0.0272 | |
| SRP219564 | SAMD11 | 148398 | RNAseq | 0.7661 | 0.4812 | |
| TCGA | SAMD11 | 148398 | RNAseq | -0.8208 | 0.0157 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by SAMD11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAMD11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAMD11 | 148398 | 3 | 7 | 20 | |
| GSE20123 | SAMD11 | 148398 | 3 | 6 | 21 | |
| GSE43470 | SAMD11 | 148398 | 1 | 5 | 37 | |
| GSE46452 | SAMD11 | 148398 | 7 | 1 | 51 | |
| GSE47630 | SAMD11 | 148398 | 8 | 4 | 28 | |
| GSE54993 | SAMD11 | 148398 | 2 | 2 | 66 | |
| GSE54994 | SAMD11 | 148398 | 15 | 2 | 36 | |
| GSE60625 | SAMD11 | 148398 | 0 | 0 | 11 | |
| GSE74703 | SAMD11 | 148398 | 1 | 3 | 32 | |
| GSE74704 | SAMD11 | 148398 | 3 | 0 | 17 | |
| TCGA | SAMD11 | 148398 | 14 | 20 | 62 |
Total number of gains: 57; Total number of losses: 50; Total Number of normals: 381.
Somatic mutations of SAMD11:
Generating mutation plots.
Highly correlated genes for SAMD11:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAMD11 | CCDC28B | 0.668378 | 3 | 0 | 3 |
| SAMD11 | SALL1 | 0.645507 | 3 | 0 | 3 |
| SAMD11 | SSC5D | 0.644305 | 3 | 0 | 3 |
| SAMD11 | RPS6KA2 | 0.639598 | 3 | 0 | 3 |
| SAMD11 | SLC25A20 | 0.637376 | 3 | 0 | 3 |
| SAMD11 | ENG | 0.633745 | 3 | 0 | 3 |
| SAMD11 | DAB2 | 0.631452 | 3 | 0 | 3 |
| SAMD11 | HTRA3 | 0.625737 | 3 | 0 | 3 |
| SAMD11 | CSPG4 | 0.614741 | 3 | 0 | 3 |
| SAMD11 | EVC | 0.608616 | 3 | 0 | 3 |
| SAMD11 | MOG | 0.59875 | 4 | 0 | 3 |
| SAMD11 | SMAD6 | 0.597682 | 3 | 0 | 3 |
| SAMD11 | ZNF521 | 0.596245 | 3 | 0 | 3 |
| SAMD11 | SDC3 | 0.592985 | 3 | 0 | 3 |
| SAMD11 | APBB1 | 0.589115 | 5 | 0 | 4 |
| SAMD11 | LRP1 | 0.588923 | 4 | 0 | 4 |
| SAMD11 | ARNT2 | 0.586843 | 4 | 0 | 3 |
| SAMD11 | FBN1 | 0.586225 | 3 | 0 | 3 |
| SAMD11 | DNAJB5 | 0.583043 | 4 | 0 | 3 |
| SAMD11 | ANGPTL2 | 0.582867 | 3 | 0 | 3 |
For details and further investigation, click here
