| Full name: SET binding factor 1 | Alias Symbol: MTMR5|DENND7A | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 6305 | HGNC ID: HGNC:10542 | Ensembl Gene: ENSG00000100241 | OMIM ID: 603560 |
| Drug and gene relationship at DGIdb | |||
Expression of SBF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SBF1 | 6305 | 39835_at | 0.2349 | 0.5716 | |
| GSE20347 | SBF1 | 6305 | 39835_at | -0.3865 | 0.0024 | |
| GSE23400 | SBF1 | 6305 | 39835_at | -0.2186 | 0.0000 | |
| GSE26886 | SBF1 | 6305 | 213383_at | -0.2276 | 0.4338 | |
| GSE29001 | SBF1 | 6305 | 213383_at | -0.0877 | 0.7506 | |
| GSE38129 | SBF1 | 6305 | 39835_at | -0.2717 | 0.0154 | |
| GSE45670 | SBF1 | 6305 | 39835_at | -0.1132 | 0.3477 | |
| GSE53622 | SBF1 | 6305 | 129913 | -1.1257 | 0.0000 | |
| GSE53624 | SBF1 | 6305 | 87146 | -0.4107 | 0.0000 | |
| GSE63941 | SBF1 | 6305 | 39835_at | 0.5431 | 0.1580 | |
| GSE77861 | SBF1 | 6305 | 39835_at | -0.0621 | 0.7721 | |
| GSE97050 | SBF1 | 6305 | A_33_P3238410 | -0.2756 | 0.3069 | |
| SRP007169 | SBF1 | 6305 | RNAseq | -0.9270 | 0.0097 | |
| SRP008496 | SBF1 | 6305 | RNAseq | -0.9835 | 0.0000 | |
| SRP064894 | SBF1 | 6305 | RNAseq | -0.2744 | 0.1573 | |
| SRP133303 | SBF1 | 6305 | RNAseq | -0.4882 | 0.0025 | |
| SRP159526 | SBF1 | 6305 | RNAseq | -0.3642 | 0.1196 | |
| SRP193095 | SBF1 | 6305 | RNAseq | -0.0000 | 0.9997 | |
| SRP219564 | SBF1 | 6305 | RNAseq | -0.4446 | 0.0979 | |
| TCGA | SBF1 | 6305 | RNAseq | -0.0814 | 0.1032 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SBF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SBF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SBF1 | 6305 | 3 | 8 | 19 | |
| GSE20123 | SBF1 | 6305 | 3 | 8 | 19 | |
| GSE43470 | SBF1 | 6305 | 2 | 8 | 33 | |
| GSE46452 | SBF1 | 6305 | 31 | 2 | 26 | |
| GSE47630 | SBF1 | 6305 | 9 | 4 | 27 | |
| GSE54993 | SBF1 | 6305 | 4 | 6 | 60 | |
| GSE54994 | SBF1 | 6305 | 11 | 8 | 34 | |
| GSE60625 | SBF1 | 6305 | 5 | 0 | 6 | |
| GSE74703 | SBF1 | 6305 | 2 | 6 | 28 | |
| GSE74704 | SBF1 | 6305 | 1 | 4 | 15 | |
| TCGA | SBF1 | 6305 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of SBF1:
Generating mutation plots.
Highly correlated genes for SBF1:
Showing top 20/366 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SBF1 | COX19 | 0.719063 | 3 | 0 | 3 |
| SBF1 | ZDHHC21 | 0.704288 | 3 | 0 | 3 |
| SBF1 | CLPS | 0.649618 | 3 | 0 | 3 |
| SBF1 | CLIP1 | 0.649113 | 4 | 0 | 4 |
| SBF1 | CCNG2 | 0.649032 | 5 | 0 | 5 |
| SBF1 | DDI2 | 0.647666 | 3 | 0 | 3 |
| SBF1 | PTPN23 | 0.645203 | 3 | 0 | 3 |
| SBF1 | GOLGA6L9 | 0.635089 | 3 | 0 | 3 |
| SBF1 | SREBF2 | 0.630913 | 10 | 0 | 10 |
| SBF1 | ABHD5 | 0.629966 | 6 | 0 | 5 |
| SBF1 | PPP6C | 0.629936 | 7 | 0 | 6 |
| SBF1 | BIRC6 | 0.626918 | 4 | 0 | 4 |
| SBF1 | TEX264 | 0.625803 | 3 | 0 | 3 |
| SBF1 | ZBTB43 | 0.62561 | 6 | 0 | 6 |
| SBF1 | TOLLIP | 0.616901 | 7 | 0 | 7 |
| SBF1 | ASCC2 | 0.615786 | 10 | 0 | 7 |
| SBF1 | TSTD1 | 0.611072 | 3 | 0 | 3 |
| SBF1 | PDCD6IP | 0.610722 | 5 | 0 | 5 |
| SBF1 | HPS5 | 0.610243 | 4 | 0 | 3 |
| SBF1 | TAX1BP1 | 0.606835 | 7 | 0 | 5 |
For details and further investigation, click here
