| Full name: KDEL endoplasmic reticulum protein retention receptor 1 | Alias Symbol: ERD2.1|ERD2|HDEL | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 10945 | HGNC ID: HGNC:6304 | Ensembl Gene: ENSG00000105438 | OMIM ID: 131235 |
| Drug and gene relationship at DGIdb | |||
Expression of KDELR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KDELR1 | 10945 | 1555575_a_at | 0.2032 | 0.3837 | |
| GSE20347 | KDELR1 | 10945 | 200922_at | -0.1089 | 0.4967 | |
| GSE23400 | KDELR1 | 10945 | 200922_at | 0.2979 | 0.0000 | |
| GSE26886 | KDELR1 | 10945 | 1555575_a_at | 0.0098 | 0.9684 | |
| GSE29001 | KDELR1 | 10945 | 200922_at | 0.0289 | 0.9038 | |
| GSE38129 | KDELR1 | 10945 | 200922_at | 0.2601 | 0.0862 | |
| GSE45670 | KDELR1 | 10945 | 1555575_a_at | 0.2216 | 0.0430 | |
| GSE53622 | KDELR1 | 10945 | 104627 | 0.2511 | 0.0000 | |
| GSE53624 | KDELR1 | 10945 | 104627 | 0.4046 | 0.0000 | |
| GSE63941 | KDELR1 | 10945 | 1555575_a_at | -0.2278 | 0.4111 | |
| GSE77861 | KDELR1 | 10945 | 1555575_a_at | 0.0623 | 0.8102 | |
| GSE97050 | KDELR1 | 10945 | A_23_P4919 | 0.4632 | 0.1223 | |
| SRP007169 | KDELR1 | 10945 | RNAseq | -0.5561 | 0.0765 | |
| SRP008496 | KDELR1 | 10945 | RNAseq | -0.7007 | 0.0002 | |
| SRP064894 | KDELR1 | 10945 | RNAseq | 0.6750 | 0.0072 | |
| SRP133303 | KDELR1 | 10945 | RNAseq | 0.3686 | 0.0290 | |
| SRP159526 | KDELR1 | 10945 | RNAseq | 0.5132 | 0.0678 | |
| SRP193095 | KDELR1 | 10945 | RNAseq | 0.0206 | 0.8919 | |
| SRP219564 | KDELR1 | 10945 | RNAseq | 0.4477 | 0.0719 | |
| TCGA | KDELR1 | 10945 | RNAseq | 0.0208 | 0.6156 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KDELR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KDELR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KDELR1 | 10945 | 4 | 4 | 22 | |
| GSE20123 | KDELR1 | 10945 | 4 | 3 | 23 | |
| GSE43470 | KDELR1 | 10945 | 4 | 11 | 28 | |
| GSE46452 | KDELR1 | 10945 | 45 | 1 | 13 | |
| GSE47630 | KDELR1 | 10945 | 9 | 6 | 25 | |
| GSE54993 | KDELR1 | 10945 | 17 | 4 | 49 | |
| GSE54994 | KDELR1 | 10945 | 4 | 14 | 35 | |
| GSE60625 | KDELR1 | 10945 | 9 | 0 | 2 | |
| GSE74703 | KDELR1 | 10945 | 4 | 7 | 25 | |
| GSE74704 | KDELR1 | 10945 | 4 | 1 | 15 | |
| TCGA | KDELR1 | 10945 | 15 | 18 | 63 |
Total number of gains: 119; Total number of losses: 69; Total Number of normals: 300.
Somatic mutations of KDELR1:
Generating mutation plots.
Highly correlated genes for KDELR1:
Showing top 20/402 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KDELR1 | SCAF1 | 0.754612 | 3 | 0 | 3 |
| KDELR1 | RNF4 | 0.713492 | 3 | 0 | 3 |
| KDELR1 | RAB7A | 0.691779 | 3 | 0 | 3 |
| KDELR1 | PPP6R1 | 0.684291 | 5 | 0 | 4 |
| KDELR1 | ARF3 | 0.683169 | 3 | 0 | 3 |
| KDELR1 | NADSYN1 | 0.681067 | 3 | 0 | 3 |
| KDELR1 | PPP1R9B | 0.679899 | 4 | 0 | 4 |
| KDELR1 | RFNG | 0.678986 | 4 | 0 | 3 |
| KDELR1 | PCNT | 0.678727 | 3 | 0 | 3 |
| KDELR1 | CSNK1D | 0.673688 | 4 | 0 | 3 |
| KDELR1 | GCDH | 0.668995 | 3 | 0 | 3 |
| KDELR1 | KDM4A | 0.668633 | 3 | 0 | 3 |
| KDELR1 | ADCK1 | 0.667476 | 3 | 0 | 3 |
| KDELR1 | NSD1 | 0.664631 | 4 | 0 | 4 |
| KDELR1 | PRDM15 | 0.658412 | 4 | 0 | 3 |
| KDELR1 | ZNF766 | 0.651846 | 3 | 0 | 3 |
| KDELR1 | PRR13 | 0.649612 | 3 | 0 | 3 |
| KDELR1 | C2CD2 | 0.647556 | 3 | 0 | 3 |
| KDELR1 | TNKS1BP1 | 0.643563 | 3 | 0 | 3 |
| KDELR1 | ARID1A | 0.642976 | 5 | 0 | 4 |
For details and further investigation, click here
