| Full name: SDE2 telomere maintenance homolog | Alias Symbol: FLJ35382 | ||
| Type: protein-coding gene | Cytoband: 1q42.12 | ||
| Entrez ID: 163859 | HGNC ID: HGNC:26643 | Ensembl Gene: ENSG00000143751 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SDE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDE2 | 163859 | 244103_at | 0.4898 | 0.1039 | |
| GSE26886 | SDE2 | 163859 | 244103_at | 0.1413 | 0.6259 | |
| GSE45670 | SDE2 | 163859 | 244103_at | 0.0839 | 0.6090 | |
| GSE53622 | SDE2 | 163859 | 70407 | 0.1273 | 0.0812 | |
| GSE53624 | SDE2 | 163859 | 70407 | 0.4994 | 0.0000 | |
| GSE63941 | SDE2 | 163859 | 244103_at | 0.3059 | 0.4179 | |
| GSE77861 | SDE2 | 163859 | 244103_at | 0.9217 | 0.0016 | |
| SRP007169 | SDE2 | 163859 | RNAseq | 0.4157 | 0.3018 | |
| SRP008496 | SDE2 | 163859 | RNAseq | 0.6866 | 0.0283 | |
| SRP064894 | SDE2 | 163859 | RNAseq | -0.1145 | 0.7157 | |
| SRP133303 | SDE2 | 163859 | RNAseq | 0.5163 | 0.0020 | |
| SRP159526 | SDE2 | 163859 | RNAseq | 0.5276 | 0.2749 | |
| SRP193095 | SDE2 | 163859 | RNAseq | 0.4001 | 0.0000 | |
| SRP219564 | SDE2 | 163859 | RNAseq | 0.3394 | 0.2820 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SDE2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SDE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDE2 | 163859 | 11 | 0 | 19 | |
| GSE20123 | SDE2 | 163859 | 11 | 0 | 19 | |
| GSE43470 | SDE2 | 163859 | 7 | 1 | 35 | |
| GSE46452 | SDE2 | 163859 | 3 | 1 | 55 | |
| GSE47630 | SDE2 | 163859 | 15 | 0 | 25 | |
| GSE54993 | SDE2 | 163859 | 0 | 6 | 64 | |
| GSE54994 | SDE2 | 163859 | 16 | 0 | 37 | |
| GSE60625 | SDE2 | 163859 | 0 | 0 | 11 | |
| GSE74703 | SDE2 | 163859 | 7 | 1 | 28 | |
| GSE74704 | SDE2 | 163859 | 5 | 0 | 15 | |
| TCGA | SDE2 | 163859 | 46 | 3 | 47 |
Total number of gains: 121; Total number of losses: 12; Total Number of normals: 355.
Somatic mutations of SDE2:
Generating mutation plots.
Highly correlated genes for SDE2:
Showing top 20/173 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDE2 | AATF | 0.699187 | 3 | 0 | 3 |
| SDE2 | SLC20A1 | 0.675949 | 3 | 0 | 3 |
| SDE2 | COQ10B | 0.661438 | 3 | 0 | 3 |
| SDE2 | SPAG5 | 0.657618 | 3 | 0 | 3 |
| SDE2 | DLX6-AS1 | 0.657608 | 4 | 0 | 3 |
| SDE2 | CMC2 | 0.648984 | 3 | 0 | 3 |
| SDE2 | COL4A1 | 0.647613 | 3 | 0 | 3 |
| SDE2 | YWHAG | 0.64314 | 4 | 0 | 3 |
| SDE2 | KLC2 | 0.641546 | 4 | 0 | 3 |
| SDE2 | USP39 | 0.640068 | 4 | 0 | 4 |
| SDE2 | AURKB | 0.639412 | 3 | 0 | 3 |
| SDE2 | PFDN2 | 0.639163 | 6 | 0 | 5 |
| SDE2 | TRIP13 | 0.628417 | 3 | 0 | 3 |
| SDE2 | ODC1 | 0.626727 | 5 | 0 | 3 |
| SDE2 | COLGALT1 | 0.625753 | 3 | 0 | 3 |
| SDE2 | FSCN1 | 0.623375 | 3 | 0 | 3 |
| SDE2 | TAF5L | 0.623331 | 4 | 0 | 3 |
| SDE2 | C17orf80 | 0.622067 | 3 | 0 | 3 |
| SDE2 | UST | 0.62109 | 3 | 0 | 3 |
| SDE2 | NUDT1 | 0.620812 | 3 | 0 | 3 |
For details and further investigation, click here
