| Full name: serpin family B member 11 (gene/pseudogene) | Alias Symbol: EPIPIN | ||
| Type: protein-coding gene | Cytoband: 18q21.33 | ||
| Entrez ID: 89778 | HGNC ID: HGNC:14221 | Ensembl Gene: ENSG00000206072 | OMIM ID: 615682 |
| Drug and gene relationship at DGIdb | |||
Expression of SERPINB11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERPINB11 | 89778 | 1552463_at | -2.8989 | 0.2279 | |
| GSE26886 | SERPINB11 | 89778 | 1552463_at | -2.8100 | 0.0000 | |
| GSE45670 | SERPINB11 | 89778 | 1552463_at | -1.4484 | 0.1516 | |
| GSE53622 | SERPINB11 | 89778 | 119119 | -2.6867 | 0.0000 | |
| GSE53624 | SERPINB11 | 89778 | 119119 | -3.3617 | 0.0000 | |
| GSE63941 | SERPINB11 | 89778 | 1552463_at | 0.2671 | 0.2233 | |
| GSE77861 | SERPINB11 | 89778 | 1552463_at | -1.7864 | 0.1901 | |
| GSE97050 | SERPINB11 | 89778 | A_23_P130411 | -0.6882 | 0.1156 | |
| SRP007169 | SERPINB11 | 89778 | RNAseq | -4.5825 | 0.0000 | |
| SRP008496 | SERPINB11 | 89778 | RNAseq | -3.0118 | 0.0010 | |
| SRP064894 | SERPINB11 | 89778 | RNAseq | -2.2643 | 0.0036 | |
| SRP133303 | SERPINB11 | 89778 | RNAseq | -3.4709 | 0.0000 | |
| SRP159526 | SERPINB11 | 89778 | RNAseq | -2.6922 | 0.0194 | |
| SRP219564 | SERPINB11 | 89778 | RNAseq | -5.1188 | 0.0001 | |
| TCGA | SERPINB11 | 89778 | RNAseq | 0.4805 | 0.5022 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by SERPINB11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERPINB11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERPINB11 | 89778 | 1 | 9 | 20 | |
| GSE20123 | SERPINB11 | 89778 | 1 | 9 | 20 | |
| GSE43470 | SERPINB11 | 89778 | 0 | 7 | 36 | |
| GSE46452 | SERPINB11 | 89778 | 1 | 26 | 32 | |
| GSE47630 | SERPINB11 | 89778 | 5 | 21 | 14 | |
| GSE54993 | SERPINB11 | 89778 | 9 | 0 | 61 | |
| GSE54994 | SERPINB11 | 89778 | 1 | 18 | 34 | |
| GSE60625 | SERPINB11 | 89778 | 0 | 4 | 7 | |
| GSE74703 | SERPINB11 | 89778 | 0 | 7 | 29 | |
| GSE74704 | SERPINB11 | 89778 | 1 | 6 | 13 | |
| TCGA | SERPINB11 | 89778 | 10 | 45 | 41 |
Total number of gains: 29; Total number of losses: 152; Total Number of normals: 307.
Somatic mutations of SERPINB11:
Generating mutation plots.
Highly correlated genes for SERPINB11:
Showing top 20/1269 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERPINB11 | TMPRSS11E | 0.810431 | 6 | 0 | 6 |
| SERPINB11 | SMIM5 | 0.801059 | 6 | 0 | 6 |
| SERPINB11 | EMP1 | 0.795902 | 6 | 0 | 6 |
| SERPINB11 | PRSS2 | 0.792666 | 4 | 0 | 4 |
| SERPINB11 | VPS4B | 0.792657 | 7 | 0 | 7 |
| SERPINB11 | CYSRT1 | 0.791628 | 6 | 0 | 6 |
| SERPINB11 | CSTB | 0.791174 | 6 | 0 | 6 |
| SERPINB11 | PLEKHM1 | 0.786991 | 7 | 0 | 7 |
| SERPINB11 | NAGK | 0.781662 | 7 | 0 | 7 |
| SERPINB11 | SLC10A5 | 0.781234 | 3 | 0 | 3 |
| SERPINB11 | IL36A | 0.774888 | 6 | 0 | 6 |
| SERPINB11 | TRIP10 | 0.774855 | 7 | 0 | 7 |
| SERPINB11 | SCEL | 0.772965 | 7 | 0 | 7 |
| SERPINB11 | ANXA9 | 0.765927 | 7 | 0 | 7 |
| SERPINB11 | ECM1 | 0.764648 | 6 | 0 | 6 |
| SERPINB11 | CASC3 | 0.763447 | 3 | 0 | 3 |
| SERPINB11 | ABLIM1 | 0.762825 | 7 | 0 | 7 |
| SERPINB11 | C18orf25 | 0.761249 | 7 | 0 | 7 |
| SERPINB11 | PRSS27 | 0.759467 | 7 | 0 | 6 |
| SERPINB11 | TTC9 | 0.759381 | 7 | 0 | 7 |
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